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Frederick J. Sannajust

Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia
2007 · Zhihe Li, Ying Zhang, et al. · Hypertension · 263
Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias
2019 · Elisa Passini, Cristian Trovato, et al. · British Journal of Pharmacology · 80
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Workshop Report
2019 · Li Pang, Philip Sager, et al. · Circulation Research · 76
Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment
2016 · Xiaoyu Zhang, Liang Guo, et al. · Journal of Pharmacological and Toxicological Methods · 75
Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits.
1996 · C K Chan, F Sannajust, et al. · Journal of Pharmacology and Experimental Therapeutics · 70
Expression of c-fos and NGFI-A messenger RNA in the medulla oblongata of the anaesthetized rat following stimulation of vagal and cardiovascular afferents
1992 · S.D. Rutherfurd, R.E. Widdop, et al. · Molecular Brain Research · 49
Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes
2016 · Haoyu Zeng, Maria I. Roman, et al. · Journal of Pharmacological and Toxicological Methods · 35
Continuous Light Exposure and Sympathectomy Suppress Circadian Rhythm of Blood Pressure in Rats
2004 · S. A. Briaud, B. L. Zhang, et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 33
Cardiovascular Consequences of Organophosphorus Poisoning and of Antidotes in Conscious Unrestrained Rats
1990 · A. Bataillard, F. Sannajust, et al. · Pharmacology & Toxicology · 31
Assessing Drug-Induced Long QT and Proarrhythmic Risk Using Human Stem-Cell-Derived Cardiomyocytes in a Ca2+ Imaging Assay: Evaluation of 28 CiPA Compounds at Three Test Sites
2019 · Hua Rong Lu, Haoyu Zeng, et al. · Toxicological Sciences · 28
L 4 ‐ Importance of Imidazoline Receptors in the Cardiovascular Responses to Clonidine and Rilmenidine in Conscious Rabbits
1992 · G.A. Head, F. Sannajust · Fundamental and Clinical Pharmacology · 28
HiPSC-CMs from different sex and ethnic origin donors exhibit qualitatively different responses to several classes of pharmacological challenges
2019 · Haoyu Zeng, Jixin Wang, et al. · Journal of Pharmacological and Toxicological Methods · 25
Assessment of the clinical cardiac drug‐drug interaction associated with the combination of hepatitis C virus nucleotide inhibitors and amiodarone in guinea pigs and rhesus monkeys
2016 · Christopher P. Regan, Pierre Morissette, et al. · Hepatology · 25
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Response of human induced pluripotent stem cell-derived cardiomyocytes to several pharmacological agents when intrinsic syncytial pacing is overcome by acute external stimulation
2018 · Haoyu Zeng, Bharathi Balasubramanian, et al. · Journal of Pharmacological and Toxicological Methods · 22
Interaction between amiodarone and hepatitis-C virus nucleotide inhibitors in human induced pluripotent stem cell-derived cardiomyocytes and HEK-293 Cav 1.2 over-expressing cells
2016 · Armando Lagrutta, Haoyu Zeng, et al. · Toxicology and Applied Pharmacology · 21
QT interval correction assessment in the anesthetized guinea pig
2015 · Pierre Morissette, Hillary K. Regan, et al. · Journal of Pharmacological and Toxicological Methods · 19
Resolving the Reversed Rate Effect of Calcium Channel Blockers on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and the Impact on In Vitro Cardiac Safety Evaluation
2018 · Haoyu Zeng, Jixin Wang, et al. · Toxicological Sciences · 18
Shortening of the electromechanical window in the ketamine/xylazine-anesthetized guinea pig model to assess pro-arrhythmic risk in early drug development
2016 · P. Morissette, C. Regan, et al. · Journal of Pharmacological and Toxicological Methods · 18
Application of a systems pharmacology model for translational prediction of hERG ‐mediated QT c prolongation
2016 · Verena Gotta, Zhiyi Yu, et al. · Pharmacology Research & Perspectives · 17
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CARDIOVASCULAR EFFECTS OF RILMENIDINE, A NEW α2‐ADRENOCEPTOR AGONIST, AND CLONIDINE IN CONSCIOUS SPONTANEOUSLY HYPERTENSIVE RATS
1989 · F. Sannajust, C. Julien, et al. · Clinical and Experimental Pharmacology and Physiology · 17
Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry
2017 · Armando Lagrutta, Christopher P. Regan, et al. · Scientific Reports · 16
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Sensitivity of pharmacokinetic–pharmacodynamic analysis for detecting small magnitudes of QTc prolongation in preclinical safety testing
2014 · Verena Gotta, Frank Cools, et al. · Journal of Pharmacological and Toxicological Methods · 16
Inter‐study variability of preclinical in vivo safety studies and translational exposure– QTc relationships – a PKPD meta‐analysis
2015 · V Gotta, F Cools, et al. · British Journal of Pharmacology · 15
Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay
2020 · Pierre Morissette, Sebastian Polak, et al. · Toxicology and Applied Pharmacology · 9
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Characterization of an investigative safety pharmacology model to assess comprehensive cardiac function and structure in chronically instrumented conscious beagle dogs
2016 · Christopher P. Regan, Gary L. Stump, et al. · Journal of Pharmacological and Toxicological Methods · 8
Works count: 65
Citation count: 1,059
H-index: 18
I10-index: 23
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