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Lutz Arne Mueller

Observed names: L Mueller, L. A. Mueller, L. Mueller, L.A. Mueller, Lauren Mueller, Lutz A Mueller, Lutz A. Mueller, Lutz Mueller, Mueller, Lauren
Observed institutions: F. Hoffmann-La Roche AG, Federal Institute for Drugs and Medical Devices, Novartis (Switzerland), National Institute on Drug Abuse, Friedrich-Alexander-Universität Erlangen-Nürnberg, Johannes Gutenberg University Mainz, Medizinische Hochschule Hannover, Universitätsklinikum Erlangen
ORCID: 0000-0001-6179-2759
Observed ORCID: 0000-0001-6179-2759
OpenAlex ID: A5110044929
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2 ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)
2018 · Hasane Ratni, Martin Ebeling, et al. · Journal of Medicinal Chemistry · 575
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs
2018 · Agnès Poirier, Marla Weetall, et al. · Pharmacology Research & Perspectives · 181
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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy
2016 · Hasane Ratni, Gary M. Karp, et al. · Journal of Medicinal Chemistry · 118
Risdiplam for Prenatal Therapy of Spinal Muscular Atrophy
2025 · Richard S. Finkel, Samuel H. Hughes, et al. · New England Journal of Medicine · 74
Structure–activity considerations and in vitro approaches to assess the genotoxicity of 19 methane-, benzene- and toluenesulfonic acid esters
2004 · Susanne Glowienke, Wilfried Frieauff, et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 57
Excellent results with cementless total hip arthroplasty and alumina-on-alumina pairing: minimum ten-year follow-up
2010 · Alexander M. Kress, Rainer Schmidt, et al. · International Orthopaedics · 49
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Periacetabular bone changes after uncemented total hip arthroplasty evaluated by quantitative computed tomography
2006 · Lutz Arne Mueller, Alexander Kress, et al. · Acta Orthopaedica · 46
Risdiplam treatment has not led to retinal toxicity in patients with spinal muscular atrophy
2020 · Robert C. Sergott, Giulia M. Amorelli, et al. · Annals of Clinical and Translational Neurology · 42
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Prospective study of a cementless total hip arthroplasty with a collum femoris preserving stem and a trabeculae oriented pressfit cup: minimun 6-year follow-up
2010 · Melanie Nowak, Tobias E. Nowak, et al. · Archives of Orthopaedic and Trauma Surgery · 41
Use of orthoses and orthopaedic technical devices in proximal spinal muscular atrophy. Results of survey in 194 SMA patients
2010 · Albert Fujak, Carsten Kopschina, et al. · Disability and Rehabilitation Assistive Technology · 40
Modes of periacetabular load transfer to cortical and cancellous bone after cemented versus uncemented total hip arthroplasty: A prospective study using computed tomography‐assisted osteodensitometry
2008 · Lutz Arne Mueller, Rainer Schmidt, et al. · Journal of Orthopaedic Research® · 39
The phenomenon and efficiency of ligamentotaxis after dorsal stabilization of thoracolumbar burst fractures
2006 · L. A. Mueller, L. P. Mueller, et al. · Archives of Orthopaedic and Trauma Surgery · 39
Stress-related femoral cortical and cancellous bone density loss after collum femoris preserving uncemented total hip arthroplasty: a prospective 7-year follow-up with quantitative computed tomography
2012 · Alexander M. Kress, Rainer Schmidt, et al. · Archives of Orthopaedic and Trauma Surgery · 38
Fractures in proximal spinal muscular atrophy
2010 · Albert Fujak, Carsten Kopschina, et al. · Archives of Orthopaedic and Trauma Surgery · 36
Quantitative computer-assisted osteodensitometry in total hip arthroplasty
2006 · R. P. Pitto, L. A. Mueller, et al. · International Orthopaedics · 29
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Osteodensitometry after total hip replacement with uncemented taper-design stem
2004 · Rainer Schmidt, Tobias E. Nowak, et al. · International Orthopaedics · 28
Progressive femoral cortical and cancellous bone density loss after uncemented tapered-design stem fixation
2010 · Lutz A Mueller, Tobias E Nowak, et al. · Acta Orthopaedica · 27
An ABJS Best Paper:
2007 · Lutz A Mueller, Michael Voelk, et al. · Clinical Orthopaedics and Related Research · 27
Addressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier Risdiplam
2021 · Stephen Fowler, Andreas Brink, et al. · Drug Metabolism and Disposition · 24
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Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report
2006 · Peter Kasper, Yoshifumi Uno, et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 24
Hypothenar Hammer Syndrome in a Golf Player: A Case Report
2000 · L. P. Mueller, L. A. Mueller, et al. · The American Journal of Sports Medicine · 24
Ultrasound-Guided Spinal Fracture Repositioning, Ligamentotaxis, and Remodeling After Thoracolumbar Burst Fractures
2006 · Lutz Arne Mueller, Jürgen Degreif, et al. · Spine · 22
Quantitative Computed Tomography-Assisted Osteodensitometry of the Pelvis After Press-Fit Cup Fixation
2011 · Alexander M. Kress, Rainer Schmidt, et al. · Journal of Bone and Joint Surgery · 21
Clinical outcome and periprosthetic bone remodelling of an uncemented femoral component with taper design
2003 · Rainer Schmidt, Lutz Mueller, et al. · International Orthopaedics · 20
In vitro mutagenicity studies on cyproterone acetate using female rat hepatocytes for metabolic activation and as indicator cells
1995 · P. Kasper, K. Tegethoff, et al. · Carcinogenesis · 20
Works count: 65
Citation count: 1,856
H-index: 22
I10-index: 36
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