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Vsevolod E. Kostrubsky
Observed names:
V E Kostrubsky,
V. E. Kostrubsky,
Vsevolod E Kostrubsky,
Vsevolod Kostrubsky
Institution:
Johnson & Johnson Vision Care (United States)
Observed institutions:
Dartmouth College,
University of Pittsburgh,
Pfizer (United States),
White River Junction VA Medical Center,
University of Pittsburgh Medical Center,
Dartmouth Health,
Johnson & Johnson Vision Care (United States)
show all 7
OpenAlex ID:
A5110048663
The Use of Human Hepatocyte Cultures to Study the Induction of Cytochrome P-450
1999
·
Vsevolod E. Kostrubsky
, Vinod Ramachandran
, et al.
·
Drug Metabolism and Disposition
·
141
Evaluation of Hepatotoxic Potential of Drugs by Inhibition of Bile-Acid Transport in Cultured Primary Human Hepatocytes and Intact Rats
2003
·
V. E. Kostrubsky
·
Toxicological Sciences
·
132
Morphogenetic Events in Mixed Cultures of Rat Hepatocytes and Nonparenchymal Cells Maintained in Biological Matrices in the Presence of Hepatocyte Growth Factor and Epidermal Growth Factor
1999
·
George K. Michalopoulos
, William C. Bowen
, et al.
·
Hepatology
·
124
PDF
Induction of Cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but Not of CYP2C9, CYP2C19, Multidrug Resistance (MDR-1) and Multidrug Resistance Associated Protein (MRP-1) by Prototypical Inducers in Human Hepatocytes
2000
·
Dieter Runge
, Christoph Köhler
, et al.
·
Biochemical and Biophysical Research Communications
·
116
Role of Hepatic Transporters in the Disposition and Hepatotoxicity of a HER2 Tyrosine Kinase Inhibitor CP-724,714
2009
·
Bo Feng
, Jinghai J. Xu
, et al.
·
Toxicological Sciences
·
80
Induction of Cytochrome P4503A by Taxol in Primary Cultures of Human Hepatocytes
1998
·
Vsevolod E. Kostrubsky
, Lionel D. Lewis
, et al.
·
Archives of Biochemistry and Biophysics
·
75
PDF
The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
2000
·
Vsevolod E. Kostrubsky
, Jacqueline F. Sinclair
, et al.
·
Drug Metabolism and Disposition
·
72
Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity
2006
·
Herbert C. Yohe
, Kimberley A. O'Hara
, et al.
·
American Journal of Physiology-Gastrointestinal and Liver Physiology
·
69
Role of CYP3A and CYP2E1 in Alcohol-Mediated Increases in Acetaminophen Hepatotoxicity: Comparison of Wild-Type and Cyp2e1(–/–) Mice
2007
·
Kristina K. Wolf
, Sheryl G. Wood
, et al.
·
Drug Metabolism and Disposition
·
58
Effect of Arsenite on Induction of CYP1A, CYP2B, and CYP3A in Primary Cultures of Rat Hepatocytes
1999
·
Judith M. Jacobs
, Calen E. Nichols
, et al.
·
Toxicology and Applied Pharmacology
·
54
PDF
Role of CYP3A in Ethanol-Mediated Increases in Acetaminophen Hepatotoxicity
1997
·
Vsevolod E. Kostrubsky
, Juliana G. Szakacs
, et al.
·
Toxicology and Applied Pharmacology
·
53
PDF
Epidermal growth factor- and hepatocyte growth factor-receptor activity in serum-free cultures of human hepatocytes
1999
·
Dorothee M Runge
, Dieter Runge
, et al.
·
Journal of Hepatology
·
52
Effects of Bergamottin on Human and Monkey Drug-Metabolizing Enzymes in Primary Cultured Hepatocytes
2002
·
Yuan Hua Wen
, Jasminder Sahi
, et al.
·
Drug Metabolism and Disposition
·
48
The effect of troglitazone biliary excretion on metabolite distribution and cholestasis in transporter-deficient rats.
2001
·
V E Kostrubsky
, M Vore
, et al.
·
PubMed
·
48
Acetaminophen hepatotoxicity precipitated by short-term treatment of rats with ethanol and isopentanol
2000
·
Jacqueline F Sinclair
, Juliana G Szakacs
, et al.
·
Biochemical Pharmacology
·
37
In vitro effects of ethanol and mouthrinse on permeability in an oral buccal mucosal tissue construct
2011
·
Francis Koschier
, Vsevolod Kostrubsky
, et al.
·
Food and Chemical Toxicology
·
36
ARSENITE DECREASES CYP3A4 AND RXRα IN PRIMARY HUMAN HEPATOCYTES
2005
·
Trisha L. Noreault
, Vsevolod E. Kostrubsky
, et al.
·
Drug Metabolism and Disposition
·
36
Acute hepatotoxicity of acetaminophen in rats treated with ethanol plus isopentanol
1995
·
Vsevolod E. Kostrubsky
, Sheryl G. Wood
, et al.
·
Biochemical Pharmacology
·
36
Effect of Taxol on Cytochrome P450 3A and Acetaminophen Toxicity in Cultured Rat Hepatocytes: Comparison to Dexamethasone
1997
·
Vsevolod E. Kostrubsky
, Lionel D. Lewis
, et al.
·
Toxicology and Applied Pharmacology
·
33
Protection of ethanol-mediated acetaminophen hepatotoxicity by triacetyloleandomycin, a specific inhibitor of CYP3A.
1997
·
V E Kostrubsky
, J G Szakacs
, et al.
·
PubMed
·
17
Hepatobiliary Disposition in Primary Cultures of Dog and Monkey Hepatocytes
2006
·
Kelly A. Rose
, Vsevolod Kostrubsky
, et al.
·
Molecular Pharmaceutics
·
13
Letter
2003
·
V. E. Kostrubsky
·
Toxicological Sciences
·
2
Response Letter to Food and Chemical Toxicology (23 Dec 2011)
2012
·
Francis Koschier
, Vsevolod Kostrubsky
, et al.
·
Food and Chemical Toxicology
·
1
Integrated Approach to the Assessment of Acetaminophen Hepatoxicity: Reduction of “Omics” and New Technology to Practice
2004
·
Dominique J. Brees
, Vsevolod Kostrubsky
, et al.
·
Toxicologic Pathology
·
1
PDF
Erratum to ‘‘In vitro effects of ethanol and mouthrinse on permeability in an oral buccal mucosal tissue construct” [49 (10) 2524–2529]
2012
·
Francis Koschier
, Vsevolod Kostrubsky
, et al.
·
Food and Chemical Toxicology
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Works count:
26
Citation count:
1,334
H-index:
19
I10-index:
21
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