Author

Mitsuo Nagai

Observed names: M Nagai, Mitsuo NAGAI, Mitsuo. Nagai

Observed institutions: University of Pittsburgh, Tohoku University, Hoshi University, Mercian Corporation (Japan), Eisai (Japan)

OpenAlex ID: A5110053593

Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D

2007 · Regina M. Kanada, Daisuke Itoh, et al. · Angewandte Chemie International Edition · 93

Syntheses and Structure−Activity Relationships of 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-quinoxaline Derivatives with Retinoic Acid Receptor α Agonistic Activity

2000 · Kouichi Kikuchi, Shigeki Hibi, et al. · Journal of Medicinal Chemistry · 44

A novel strategy for the stereoselective total synthesis of C-17 spiro steroids. Total synthesis of 19-norcanrenone - a formal total synthesis of 19-norspironolactone

1988 · Hideo. Nemoto, Shigekazu. Fujita, et al. · Journal of the American Chemical Society · 41

First enantioselective total synthesis of (+)-cortisone

1990 · Hideo Nemoto, Norikazu Matsuhashi, et al. · The Journal of Organic Chemistry · 40

Discovery of Novel and Potent Retinoic Acid Receptor α Agonists: Syntheses and Evaluation of Benzofuranyl-pyrrole and Benzothiophenyl-pyrrole Derivatives

2000 · Hiroyuki Yoshimura, Kouichi Kikuchi, et al. · Journal of Medicinal Chemistry · 31

Syntheses and Structure−Activity Relationships of Novel Retinoid X Receptor Agonists

1998 · Shigeki Hibi, Kouichi Kikuchi, et al. · Journal of Medicinal Chemistry · 27

Acyclic Stereocontrol in Additions of Grignard Reagents to α-Alkoxyiminium Ions. A Stereoselective Approach tothreoAmino Ethers

1992 · Mitsuo Nagai, John J. Gaudino, et al. · Synthesis · 26

Syntheses of bicyclo[3.3.0]octanes via bifurcating radical cyclization pathways

1990 · Mitsuo Nagai, Jerome Lazor, et al. · The Journal of Organic Chemistry · 24

High diastereoselection in the intramolecular Diels–Alder reaction of o-quinodimethanes: an expedient entry to trans-benzoperhydrindans. A highly stereoselective total synthesis of (±)-estrone and (±)-adrenosterone

1989 · Hideo Nemoto, Mitsuo Nagai, et al. · Journal of the Chemical Society Perkin Transactions 1 · 24

A highly stereoselective total synthesis of (±)-estrone and (±)-adrenosterone

1988 · Hideo Nemoto, Mitsuo Nagai, et al. · Tetrahedron Letters · 24

Syntheses and evaluation of quinoline derivatives as novel retinoic acid receptor α antagonists

2001 · Kouichi Kikuchi, Katsuya Tagami, et al. · Bioorganic & Medicinal Chemistry Letters · 23

Synthetic approach to (+)-aldosterone and its relatives. 1. Synthesis of (+)-trans-4,5-(4-methoxybenzo)-1.beta.,7a.beta.-[2.alpha.-(methoxymethyl)-5-oxofuro]hydrindan

1985 · Hideo Nemoto, Mitsuo Nagai, et al. · The Journal of Organic Chemistry · 22

E7107, a new 7-urethane derivative of pladienolide D: Discovery of a novel antitumor agent

2004 · Jun Niijima, Yoshihiko Kotake, et al. · Cancer Research · 18

A stereoselective total synthesis of Δ9-progesterone via an intramolecular cycloaddition reaction

1985 · Hideo Nemoto, Mitsuo Nagai, et al. · Tetrahedron Letters · 16

Studies on the syntheses of heterocyclic and natural compounds. Part 939

1981 · Tetsuji Kametani, Hiroo Matsumoto, et al. · Tetrahedron · 16

Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D

2007 · Regina M. Kanada, Daisuke Itoh, et al. · Angewandte Chemie · 14

A stereoselective total synthesis of 11-oxoprogesterone, a precursor to the corticosteroids, via an intramolecular cycloaddition reaction

1986 · Hideo Nemoto, Mitsuo Nagai, et al. · Journal of the Chemical Society Perkin Transactions 1 · 14

A novel stereoselective access to des-A B-aromatic corticosteroids via intramolecular cycloaddition reaction—potential intermediates for the synthesis of corticosteroids

1987 · Hideo Nemoto, Mitsuo Nagai, et al. · Journal of the Chemical Society Perkin Transactions 1 · 13

Novel retinoic acid receptor α agonists: syntheses and evaluation of pyrazole derivatives

2000 · Kouichi Kikuchi, Shigeki Hibi, et al. · Bioorganic & Medicinal Chemistry Letters · 12

A synthetic approach to (+)-aldosterone and its relatives (2)- a stereoselective synthesis of (+)--4,5-(4-methoxybenzo)- 1β , 7aβ - ( 2α-methoxymethyl- 5 -oxofuro) hydrindane

1985 · Hideo Nemoto, Mitsuo Nagai, et al. · Tetrahedron · 11

Asymmetric synthesis of trans-benzoperhydroindan: asymmetric induction in intramolecular Diels–Alder reactions of o-quinodimethanes

1988 · Hideo Nemoto, Mitsuo Nagai, et al. · Journal of the Chemical Society Perkin Transactions 1 · 10

Effect of E6060 [4-{5-[7-Fluoro-4-(trifluoromethyl)benzo[b]furan-2-yl]-1 H-2-pyrrolyl}benzoic Acid], a Novel Subtype-Selective Retinoid, on Lupus-Like Nephritis in Female (NZBxNZW)F1 Mice

2005 · Toshihiko Yamauchi, Akira Ishibashi, et al. · Journal of Pharmacology and Experimental Therapeutics · 9

Syntheses and evaluation of naphthalenyl- and chromenyl-pyrrolyl-benzoic acids as potent and selective retinoic acid receptor α agonists

2000 · Shigeki Hibi, Katsuya Tagami, et al. · Bioorganic & Medicinal Chemistry Letters · 8

A simple and stereoselective synthesis of Des-A-B-aromatic corticoids via intramolecular cycloaddition: potential intermediates for the synthesis of corticoids

1985 · Hideo Nemoto, Mitsuo Nagai, et al. · Journal of the Chemical Society Chemical Communications · 8

Existence of Retinoic Acid-Receptor-Independent Retinoid X-Receptor-Dependent Pathway in Myeloid Cell Function

2001 · Takayuki Hida, Kenji Tai, et al. · The Japanese Journal of Pharmacology · 7

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Works count: 38

Citation count: 595

H-index: 15

I10-index: 21