Author

Ted L. Underiner

Observed name: Ted Underiner

Observed institutions: Georgetown University, Sanofi (France), Chester County Hospital, Chester County Historical Society, The Ohio State University

OpenAlex ID: A5110063259

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

2010 · Ted Underiner, Torsten Herbertz, et al. · Anti-Cancer Agents in Medicinal Chemistry · 133

Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells

2005 · Weihua Wan, Mark S. Albom, et al. · Blood · 105

Diels-Alder approach to bicyclic .alpha.-hydroxy ketones. Facile ketol rearrangements of strained .alpha.-hydroxy ketones

1985 · Xavier Creary, Pamela A. Inocencio, et al. · The Journal of Organic Chemistry · 62

Designing Chemical Libraries for Lead Discovery

1996 · Allan M. Ferguson, David E. Patterson, et al. · SLAS DISCOVERY · 54

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Discovery of a Potent Inhibitor of Anaplastic Lymphoma Kinase with in Vivo Antitumor Activity

2010 · Gregory R. Ott, Rabindranath Tripathy, et al. · ACS Medicinal Chemistry Letters · 50

Alkylation of allylic derivatives. 17. Cross-coupling reactions of diallylic pivalates with butyl- and phenylcopper reagents

1991 · Ted L. Underiner, Harlan L. Goering · The Journal of Organic Chemistry · 45

Synthesis and Biological Profile of the pan-Vascular Endothelial Growth Factor Receptor/Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor-Like Homology Domains 2 (VEGF-R/TIE-2) Inhibitor 11-(2-Methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): A Novel Oncology Therapeutic Agent

2011 · Robert L. Hudkins, Nadine C. Becknell, et al. · Journal of Medicinal Chemistry · 43

Alkylation of allylic derivatives. 14. Relationship of double-bond configuration between reactant and product for cross-coupling reactions of Z-allylic carboxylates with organocopper reagents

1989 · Ted L. Underiner, Steven D. Paisley, et al. · The Journal of Organic Chemistry · 39

Stabilization demands of diethyl phosphonate substituted carbocations as revealed by substituent effects

1985 · Xavier Creary, Ted L. Underiner · The Journal of Organic Chemistry · 36

First Synthesis of Cytotoxic 8,9-Secokaurene Diterpenoids. An Enantioselective Route to (−)-O-Methylshikoccin and (+)-O-Methylepoxyshikoccin

1997 · Leo A. Paquette, Dirk Backhaus, et al. · Journal of the American Chemical Society · 33

Synthesis and structure–activity relationships of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase

2010 · Karen L. Milkiewicz, Linda R. Weinberg, et al. · Bioorganic & Medicinal Chemistry · 29

CT2108A and B: New Fatty Acid Synthase Inhibitors as Antifungal Agents

2003 · Jodi A. Laakso, Robert Raulli, et al. · Journal of Natural Products · 29

Cross coupling of allylic derivatives. 16. Regiochemistry of cross coupling of the isomeric (E,E)-3,5-heptadien-2-yl and (E,E)-2,5-heptadien-4-yl pivalates with organocopper and Grignard reagents

1990 · Ted L. Underiner, Harlan L. Goering · The Journal of Organic Chemistry · 27

Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors

2010 · Linda R. Weinberg, Mark S. Albom, et al. · Bioorganic & Medicinal Chemistry Letters · 24

Solution Phase Synthesis of Chemical Libraries for Lead Discovery

1996 · Cheryl D. Garr, John R. Peterson, et al. · SLAS DISCOVERY · 24

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Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors

2011 · Craig A. Zificsak, Jay P. Theroff, et al. · Bioorganic & Medicinal Chemistry Letters · 23

Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases

2011 · Craig A. Zificsak, Diane E. Gingrich, et al. · Bioorganic & Medicinal Chemistry Letters · 22

Structural analysis of cis-[n.3.1]bicyclic ketones by x-ray crystallography. Impact of the observed conformational crossover by .pi.-facially diastereoselective nucleophilic additions to this class of ketones and on the stereochemical course of electrophilic reactions involving their methylene analogs

1992 · Leo A. Paquette, Ted L. Underiner, et al. · The Journal of Organic Chemistry · 22

Alkylation of allylic derivatives. 13. Cross-coupling reactions of the isomeric 2,3,4,4a,5,6-hexahydro-2-naphthalenyl carboxylates with organocopper and Grignard reagents

1988 · Ted L. Underiner, Harlan L. Goering · The Journal of Organic Chemistry · 22

2,7-Pyrrolo[2,1-f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation

2011 · Linda R. Weinberg, Mark S. Albom, et al. · Bioorganic & Medicinal Chemistry Letters · 20

2,4-Diaminopyrimidine inhibitors of c-Met kinase bearing benzoxazepine anilines

2010 · Craig A. Zificsak, Jay P. Theroff, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Design and synthesis of dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole oximes as potent dual inhibitors of TIE-2 and VEGF-R2 receptor tyrosine kinases

2008 · Reddeppareddy Dandu, Allison L. Zulli, et al. · Bioorganic & Medicinal Chemistry Letters · 15

Preparation and assignment of configuration of cis- and trans-2,3,4,4a,5,6-hexahydro-2-naphthalenol

1987 · Ted L. Underiner, Harlan L. Goering · The Journal of Organic Chemistry · 15

Improvement in oral bioavailability of 2,4-diaminopyrimidine c-Met inhibitors by incorporation of a 3-amidobenzazepin-2-one group

2011 · Karen L. Milkiewicz, Lisa D. Aimone, et al. · Bioorganic & Medicinal Chemistry · 14

Cross coupling of allylic derivatives. 15. Regio- and stereospecfic cross-coupling reactions of dienyl allylic N-phenylcarbamates with phenylcopper reagents

1989 · Ted L. Underiner, Harlan L. Goering · The Journal of Organic Chemistry · 11

Works count: 34

Citation count: 953

H-index: 20

I10-index: 28