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David V. Erbe

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
2001 · Carin C. Stamper, Yan Zhang, et al. · Nature · 491
An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria
2016 · Abigail Liebow, Xingsheng Li, et al. · Journal of the American Society of Nephrology · 201
Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site
2007 · Douglas P. Wilson, Zhao-Kui Wan, et al. · Journal of Medicinal Chemistry · 162
Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent
2008 · Dean R. Artis, Jack J. Lin, et al. · Proceedings of the National Academy of Sciences · 151
Molecular activation of PPARγ by angiotensin II type 1-receptor antagonists
2006 · David V. Erbe, Katherine Gartrell, et al. · Vascular Pharmacology · 135
Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface
2013 · Michael M. Schmidt, Sharon A. Townson, et al. · Structure · 120
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Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis
2020 · Simina Ticau, Gautham V Sridharan, et al. · Neurology · 111
Ertiprotafib Improves Glycemic Control and Lowers Lipids via Multiple Mechanisms
2004 · David V. Erbe, Suyue Wang, et al. · Molecular Pharmacology · 86
Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1
2021 · Yaacov Frishberg, Georges Deschênes, et al. · Clinical Journal of the American Society of Nephrology · 84
A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia
2011 · Lacramioara Ivanciu, Raffaella Toso, et al. · Nature Biotechnology · 75
Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria
2020 · Tracy L McGregor, Karen A Hunt, et al. · eLife · 58
Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48
2006 · Zhao-Kui Wan, Jinbo Lee, et al. · Bioorganic & Medicinal Chemistry Letters · 58
Small Molecule Ligands Define a Binding Site on the Immune Regulatory Protein B7.1
2002 · David V. Erbe, Suyue Wang, et al. · Journal of Biological Chemistry · 53
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Probing acid replacements of thiophene PTP1B inhibitors
2007 · Zhao-Kui Wan, Bruce Follows, et al. · Bioorganic & Medicinal Chemistry Letters · 45
Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity
2019 · Kyle D. Wood, Ross P. Holmes, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 42
Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry
2021 · Margaret M. Parker, Scott M. Damrauer, et al. · Scientific Reports · 39
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H6PDH interacts directly with 11β-HSD1: Implications for determining the directionality of glucocorticoid catalysis
2008 · Yan-ling Zhang, Xiaotian Zhong, et al. · Archives of Biochemistry and Biophysics · 37
Structure‐Based Optimization of Protein Tyrosine Phosphatase‐1 B Inhibitors: Capturing Interactions with Arginine 24
2008 · Zhao‐Kui Wan, Jinbo Lee, et al. · ChemMedChem · 18
Fcγ receptors in cancer and infectious disease
1992 · Michael W. Fanger, David V. Erbe · Immunologic Research · 13
Mp12-14 Safety and Efficacy Study of Lumasiran, an Investigational Rna Interference (rnai) Therapeutic, in Adult and Pediatric Patients With Primary Hyperoxaluria Type 1 (ph1)
2019 · Yaacov Frishberg, Georges Deschenes, et al. · The Journal of Urology · 10
PPARδ Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities
2008 · Mylène Perreault, David V. Erbe, et al. · PPAR Research · 9
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Erratum: correction: Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
2001 · Carin C. Stamper, Yan Zhang, et al. · Nature · 9
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Transthyretin-stabilising mutation T119M is not associated with protection against vascular disease or death in the UK Biobank
2020 · Margaret M. Parker, Simina Ticau, et al. · Amyloid · 8
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An enzyme-linked immunosorbent assay to measure insulin receptor dephosphorylation by PTP1B
2007 · Yan-Ling Zhang, May Tam, et al. · Analytical Biochemistry · 5
Structure—Function Aspects of Selectin—Carbohydrate Interactions
1994 · Laurence A. Lasky, Leonard G. Presta, et al. · Springer eBooks · 4
Works count: 39
Citation count: 2,030
H-index: 18
I10-index: 20
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