Author

Benoît Villiers

Observed names: B. Villiers, B.R.M. Villiers, Benoit R. M. Villiers, Benoit R.M. Villiers, Benoit Villiers

Institutions: Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, CEA Paris-Saclay - Etablissement de Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, CEA Paris-Saclay

Observed institutions: University of Cambridge, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, CEA Paris-Saclay - Etablissement de Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, ManRos Therapeutics (France), CEA Paris-Saclay, Institut de Biologie et Technologies

OpenAlex ID: A5110073287

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

2018 · Thu Lan Nguyen, Arnaud Duchon, et al. · Disease Models & Mechanisms · 97

Directed Evolution of a Gatekeeper Domain in Nonribosomal Peptide Synthesis

2011 · Benoit Villiers, Florian Hollfelder · Chemistry & Biology · 77

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

2017 · Nadège Loaëc, Eletta Attanasio, et al. · Marine Drugs · 60

Mapping the Limits of Substrate Specificity of the Adenylation Domain of TycA

2009 · Benoit R. M. Villiers, Florian Hollfelder · ChemBioChem · 56

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor

2016 · Lyamin Z. Bendjeddou, Nadège Loaëc, et al. · European Journal of Medicinal Chemistry · 46

An optimized ATP/PPi‐exchange assay in 96‐well format for screening of adenylation domains for applications in combinatorial biosynthesis

2007 · Linda G. Otten, Michelle L. Schaffer, et al. · Biotechnology Journal · 41

Structure–Activity Relationship in the Leucettine Family of Kinase Inhibitors

2021 · Tania Tahtouh, Emilie Durieu, et al. · Journal of Medicinal Chemistry · 34

USER friendly DNA recombination (USERec): a simple and flexible near homology-independent method for gene library construction

2009 · B.R.M. Villiers, V. Stein, et al. · Protein Engineering Design and Selection · 32

Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production

2021 · Annica Saaret, Benoît Villiers, et al. · Nature Communications · 30

Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8

2018 · Katy Billot, Charlène Coquil, et al. · American Journal of Physiology-Renal Physiology · 8

USER Friendly DNA Recombination (USERec): Gene Library Construction Requiring Minimal Sequence Homology

2014 · Benoit Villiers, Florian Hollfelder · Methods in molecular biology · 2

#1603 A potent protein inhibitor of HB-EGF protects kidneys from glomerular lesions in a pig model of crescentic glomerulonephritis

2024 · Sylvain Pichard, Nassim Mahtal, et al. · Nephrology Dialysis Transplantation

A pM inhibitor of HB-EGF derived from diphtheria toxin for the treatment of HB-EGF-related diseases

2013 · B. Villiers, S. Pichard, et al. · Toxicon

22. Engineering of an HB-EGF Inhibitor from the Diphtheria Toxin Receptor–Binding Domain for the Treatment of HB-EGF-Related Diseases

2012 · Benoit Villiers, Sylvain Pichard, et al. · Toxicon

Works count: 14

Citation count: 483

H-index: 9

I10-index: 9