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F. Jenck

Promotion of sleep by targeting the orexin system in rats, dogs and humans
2007 · Catherine Brisbare-Roch, Jasper Dingemanse, et al. · Nature Medicine · 578
Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress
1997 · Francois Jenck, Jean-Luc Moreau, et al. · Proceedings of the National Academy of Sciences · 348
5-HT2C Receptor Agonists: Pharmacological Characteristics and Therapeutic Potential
1998 · J.R. Martin, M. Bös, et al. · Journal of Pharmacology and Experimental Therapeutics · 335
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat
2000 · François Jenck, Juergen Wichmann, et al. · Proceedings of the National Academy of Sciences · 275
Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats
1992 · J.-L. Moreau, F. Jenck, et al. · European Neuropsychopharmacology · 250
Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice
1999 · Anja Köster, Alexandra Montkowski, et al. · Proceedings of the National Academy of Sciences · 247
Dorsal periaqueductal gray-induced aversion as a simulation of panic anxiety: Elements of face and predictive validity
1995 · François Jenck, Jean-Luc Moreau, et al. · Psychiatry Research · 206
Urocortin, a novel neuropeptide with anxiogenic-like properties
1997 · Jean-Luc Moreau, Gavin Kilpatrick, et al. · Neuroreport · 170
Selective activation of 5HT1A receptors induces lower lip retraction in the rat
1989 · Hemmie H.G. Berendsen, François Jenck, et al. · Pharmacology Biochemistry and Behavior · 161
Involvement of 5-HT1C-receptors in drug-induced penile erections in rats
1990 · Hemmie H. G. Berendsen, François Jenck, et al. · Psychopharmacology · 151
A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity
1996 · Johan Lundkvist, Zhen Chai, et al. · European Journal of Pharmacology · 145
Chronic mild stress-induced anhedonia model of depression
1995 · J. -L. Moreau, R. Scherschlicht, et al. · Behavioural Pharmacology · 144
Some critical determinants of the behaviour of rats in the elevated plus-maze
1993 · Guy Griebel, Jean-Luc Moreau, et al. · Behavioural Processes · 139
Animal Models for Anxiety and Response to Serotonergic Drugs
2010 · C.L.E. Broekkamp, H.H.G. Berendsen, et al. · Psychopathology · 134
Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents
1994 · Guy Griebel, Jean-Luc Moreau, et al. · Psychopharmacology · 126
Drug-induced potentiation of prepulse inhibition of acoustic startle reflex in mice: a model for detecting antipsychotic activity?
2001 · Abdel-Mouttalib Ouagazzal, François Jenck, et al. · Psychopharmacology · 124
5HT2C receptor agonists exhibit antidepressant-like properties in the anhedonia model of depression in rats
1996 · J.-L. Moreau, M. Bös, et al. · European Neuropsychopharmacology · 122
Evidence for a role of 5-HT1C receptors in the antiserotonergic properties of some antidepressant drugs
1993 · François Jenck, Jean-Luc Moreau, et al. · European Journal of Pharmacology · 117
Functional Consequences of Reduction in NMDA Receptor Glycine Affinity in Mice Carrying Targeted Point Mutations in the Glycine Binding Site
2000 · James N. C. Kew, Anja Koester, et al. · Journal of Neuroscience · 104
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Pharmacological Characterization of the Novel Nonpeptide Orphanin FQ/Nociceptin Receptor Agonist Ro 64-6198: Rapid and Reversible Desensitization of the ORL1 Receptor in Vitro and Lack of Tolerance in Vivo
2001 · Frank M. Dautzenberg, Jürgen Wichmann, et al. · Journal of Pharmacology and Experimental Therapeutics · 99
Novel Agonists of 5HT 2C Receptors. Synthesis and Biological Evaluation of Substituted 2-(Indol-1-yl)-1-methylethylamines and 2-(Indeno[1,2- b ]pyrrol-1-yl)-1-methylethylamines. Improved Therapeutics for Obsessive Compulsive Disorder
1997 · Michael Bös, François Jenck, et al. · Journal of Medicinal Chemistry · 97
Discovery and Characterization of ACT‐335827, an Orally Available, Brain Penetrant Orexin Receptor Type 1 Selective Antagonist
2013 · Michel A. Steiner, John Gatfield, et al. · ChemMedChem · 95
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468
2017 · Alexander Treiber, Ruben de Kanter, et al. · Journal of Pharmacology and Experimental Therapeutics · 87
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Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies.
1992 · M Facklam, P Schoch, et al. · Journal of Pharmacology and Experimental Therapeutics · 85
Opioid receptor subtypes associated with ventral tegmental facilitation of lateral hypothalamic brain stimulation reward
1987 · François Jenck, Alain Gratton, et al. · Brain Research · 85
Works count: 155
Citation count: 7,535
H-index: 51
I10-index: 100
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