Author

Mark O. Urban

Observed names: Mark O Urban, Mark Urban, Mark O. Urban

Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)

Observed institutions: West Virginia University, University of Iowa, Merck & Co., Inc., Rahway, NJ, USA (United States)

OpenAlex ID: A5110132861

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

2008 · Samer R Eid, Eric D Crown, et al. · Molecular Pain · 453

Reversal of acid‐induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2

2010 · Jerzy Karczewski, Robert H Spencer, et al. · British Journal of Pharmacology · 126

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Nuclei within the rostral ventromedial medulla mediating morphine antinociception from the periaqueductal gray

1994 · Mark O. Urban, David J. Smith · Brain Research · 80

Dose-Dependent Pain-Facilitatory and -Inhibitory Actions of Neurotensin Are Revealed by SR 48692, a Nonpeptide Neurotensin Antagonist: Influence on the Antinociceptive Effect of Morphine,

1997 · David J. Smith, Alyssa A. Hawranko, et al. · Journal of Pharmacology and Experimental Therapeutics · 76

Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy

2011 · B. Wesley Trotter, Kausik K. Nanda, et al. · Bioorganic & Medicinal Chemistry Letters · 60

Development of Orally Bioavailable and CNS Penetrant Biphenylaminocyclopropane Carboxamide Bradykinin B 1 Receptor Antagonists

2006 · Scott D. Kuduk, Christina N. Di Marco, et al. · Journal of Medicinal Chemistry · 58

Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)

2009 · Scott D. Kuduk, Christina N. Di Marco, et al. · Bioorganic & Medicinal Chemistry Letters · 53

Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1−/− and not CB2−/− mice in models of acute and persistent pain

2009 · Nova M.H. Sain, Annie Liang, et al. · Neuropharmacology · 51

BOLD and blood volume-weighted fMRI of rat lumbar spinal cord during non-noxious and noxious electrical hindpaw stimulation

2007 · Fuqiang Zhao, Mangay Williams, et al. · NeuroImage · 50

Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)

2009 · Scott D. Kuduk, Ronald K. Chang, et al. · Bioorganic & Medicinal Chemistry Letters · 49

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice

2017 · Anthony J. Roecker, Melissa Egbertson, et al. · Bioorganic & Medicinal Chemistry Letters · 48

fMRI of pain processing in the brain: A within-animal comparative study of BOLD vs. CBV and noxious electrical vs. noxious mechanical stimulation in rat

2011 · Fuqiang Zhao, Denise Welsh, et al. · NeuroImage · 46

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model

2017 · Joseph E. Pero, Michael A. Rossi, et al. · Bioorganic & Medicinal Chemistry Letters · 37

Synthesis, Structure−Activity Relationship, and Pharmacological Profile of Analogs of The ASIC-3 Inhibitor A-317567

2009 · Scott D. Kuduk, Christina N. Di Marco, et al. · ACS Chemical Neuroscience · 37

Localization of the antinociceptive and antianalgesic effects of neurotensin within the rostral ventromedial medulla

1994 · Mark O. Urban, David J. Smith · Neuroscience Letters · 34

The role of CNS NMDA receptors and nitric oxide in visceral hyperalgesia

2001 · Santosh V Coutinho, Mark O Urban, et al. · European Journal of Pharmacology · 31

MK-8825: A potent and selective CGRP receptor antagonist with good oral activity in rats

2012 · Ian M. Bell, Craig A. Stump, et al. · Bioorganic & Medicinal Chemistry Letters · 30

Role of the Rostral Medial Medulla in the Development of Primary and Secondary Hyperalgesia after Incision in the Rat

2002 · Zeljko J. Bosnjak, Esther M. Pogatzki, et al. · Anesthesiology · 29

Medullary N-type and P/Q-type calcium channels contribute to neuropathy-induced allodynia

2005 · Mark O. Urban, Kunkun Ren, et al. · Neuroreport · 26

Discovery of 3-Substituted Aminocyclopentanes as Potent and Orally Bioavailable NR2B Subtype-Selective NMDA Antagonists

2011 · Mark E. Layton, Michael J. Kelly, et al. · ACS Chemical Neuroscience · 24

Large Animal Models for Pain Therapeutic Development

2009 · Darrell Henze, Mark Urban · Frontiers in neuroscience · 21

Decahydroquinoline amides as highly selective CB2 agonists: Role of selectivity on in vivo efficacy in a rodent model of analgesia

2011 · Peter J. Manley, Amy Zartman, et al. · Bioorganic & Medicinal Chemistry Letters · 20

Synthesis and biological evaluation of 6-aryl-6 H -pyrrolo[3,4- d ]pyridazine derivatives: high-affinity ligands to the α 2 δ subunit of voltage gated calcium channels

2004 · Brian A. Stearns, Naomi Anker, et al. · Bioorganic & Medicinal Chemistry Letters · 20

Antihyperalgesic effect of the cannabinoid agonist WIN55,212-2 is mediated through an interaction with spinal metabotropic glutamate-5 receptors in rats

2004 · Aldric T. Hama, Mark O. Urban · Neuroscience Letters · 18

Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3)

2011 · Scott D. Kuduk, Ronald K. Chang, et al. · Bioorganic & Medicinal Chemistry Letters · 16

Works count: 31

Citation count: 1,558

H-index: 21

I10-index: 30