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Nick M. Clayton

Observed names: N CLAYTON, N Clayton, N M Clayton, N. Clayton, N. M. CLAYTON, N. M. Clayton, N.M. Clayton, Nick Clayton
OpenAlex ID: A5110136019
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
2002 · N. Clayton, F. H. Marshall, et al. · Pain · 247
GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain
2005 · Jorge De Alba, Nick M. Clayton, et al. · Pain · 131
Discovery of 2-[(2,4-Dichlorophenyl)amino]- N -[(tetrahydro- 2 H -pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a Selective CB2 Receptor Agonist for the Treatment of Inflammatory Pain
2007 · Gerard M. P. Giblin, Celestine T. O'Shaughnessy, et al. · Journal of Medicinal Chemistry · 121
Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat
2005 · Steven J.R. Elmes, Lisa A. Winyard, et al. · Pain · 97
Review article: the therapeutic potential of 5‐HT3receptor antagonists in the treatment of irritable bowel syndrome
1999 · P.P.A. Humphrey, C. Bountra, et al. · Alimentary Pharmacology & Therapeutics · 94
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Early histological features of small intestinal injury induced by indomethacin
1993 · A. ANTHONY, A. P. DHILLON, et al. · Alimentary Pharmacology & Therapeutics · 77
The Cyclooxygenase-2 Inhibitor GW406381X [2-(4-Ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] Is Effective in Animal Models of Neuropathic Pain and Central Sensitization
2005 · Sharon Bingham, Paul J. Beswick, et al. · Journal of Pharmacology and Experimental Therapeutics · 63
Gastric anti‐secretory, mucosal protective, anti‐pepsin and anti‐Helicobacter properties of ranitidine bismuth citrate
1993 · R. STABLES, C. J. CAMPBELL, et al. · Alimentary Pharmacology & Therapeutics · 58
Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a Brain Penetrant 5-Azaindole CB2Agonist for the Treatment of Chronic Pain
2009 · Gerard M. P. Giblin, Andrew Billinton, et al. · Journal of Medicinal Chemistry · 55
Changes in vanilloid receptor 1 (TRPV1) expression following lingual nerve injury
2006 · James E. Biggs, Julian M. Yates, et al. · European Journal of Pain · 54
Vanilloid receptor 1 expression in human tooth pulp in relation to caries and pain.
2005 · Claire R Morgan, Helen D Rodd, et al. · PubMed · 51
Do infiltrating neutrophils contribute to the pathogenesis of indomethacin induced ulceration of the rat gastric antrum?
1993 · M A Trevethick, N M Clayton, et al. · Gut · 51
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Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors
2004 · Paul Beswick, Sharon Bingham, et al. · Bioorganic & Medicinal Chemistry Letters · 46
Activation of the α7-Nicotinic Acetylcholine Receptor Reverses Complete Freund Adjuvant–Induced Mechanical Hyperalgesia in the Rat Via a Central Site of Action
2008 · Stephen J. Medhurst, Jon P. Hatcher, et al. · Journal of Pain · 43
Pyridine-3-carboxamides as novel CB2 agonists for analgesia
2008 · William L. Mitchell, Gerard M.P. Giblin, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Effect of SB-750364, a specific TRPV1 receptor antagonist, on injury-induced ectopic discharge in the lingual nerve
2008 · James E. Biggs, Julian M. Yates, et al. · Neuroscience Letters · 23
Identification of novel pyrazole acid antagonists for the EP1 receptor
2006 · Stephen C. McKeown, Adrian Hall, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
2009 · Martin E. Swarbrick, Paul J. Beswick, et al. · Bioorganic & Medicinal Chemistry Letters · 22
Neutrophil infiltration does not contribute to the ulcerogenic effects of indomethacin in the rat gastric antrum
1994 · M. A. Trevethick, A. K. Bahl, et al. · Inflammation Research · 19
5‐HT4receptors are not involved in the control of small intestinal transit in the fasted conscious rat
1996 · N. M. CLAYTON, J. D. GALE · Neurogastroenterology & Motility · 18
Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain
2010 · James W. Myatt, Mark P. Healy, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Vanilloid receptor 1 (TRPV1) expression in lingual nerve neuromas from patients with or without symptoms of burning pain
2006 · James E. Biggs, Julian M. Yates, et al. · Brain Research · 15
Comparison of the profiles of agonists as stimulants of the β3‐adrenoceptor in vitro with their gastroprotective effects in the conscious rat
1996 · A.K. Bahl, N.M. Clayton, et al. · British Journal of Pharmacology · 13
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An NMR-based metabolic profiling study of inflammatory pain using the rat FCA model
2007 · S. C. Connor, R. A. Gray, et al. · Metabolomics · 12
5-HT, receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat
2001 · Gareth A. Hicks, Nick M. Clayton, et al. · Gastroenterology · 11
Works count: 64
Citation count: 1,483
H-index: 19
I10-index: 27
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