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Hon‐Wah Man
Observed names:
H.-W. Man,
H.‐W. MAN,
Hon Wah Man,
Hon-Wah Man
Observed institutions:
DuPont (United States),
Iowa State University,
Celgene (United States),
Washington State University
OpenAlex ID:
A5110152126
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
2015
·
Jan Krönke
, Emma C. Fink
, et al.
·
Nature
·
883
Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity
2014
·
P.H. Schafer
, A. Parton
, et al.
·
Cellular Signalling
·
315
PDF
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
2017
·
Mary E. Matyskiela
, Weihong Zhang
, et al.
·
Journal of Medicinal Chemistry
·
313
The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
2008
·
Ling Lu
, Faribourz Payvandi
, et al.
·
Microvascular Research
·
228
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
2015
·
Patrick R. Hagner
, Hon-Wah Man
, et al.
·
Blood
·
207
PDF
Discovery of ( S )- N -{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1 H -isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor
2009
·
Hon-Wah Man
, Peter Schafer
, et al.
·
Journal of Medicinal Chemistry
·
187
Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs
2003
·
Peter H. Schafer
, Anita K. Gandhi
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
186
Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry
1996
·
Donald S. Matteson
, Hon-Wah Man
, et al.
·
Journal of the American Chemical Society
·
89
Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
2017
·
Joshua D. Hansen
, Kevin Condroski
, et al.
·
Journal of Medicinal Chemistry
·
77
Hydrolysis of Substituted 1,3,2-Dioxaborolanes and an Asymmetric Synthesis of a Differentially Protected syn,syn-3-Methyl-2,4-hexanediol
1996
·
Donald S. Matteson
, Hon-Wah Man
·
The Journal of Organic Chemistry
·
62
Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity
2012
·
Alexander L. Ruchelman
, Hon-Wah Man
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
61
Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies
1998
·
Prabhakar K. Jadhav
, Francis J. Woerner
, et al.
·
Journal of Medicinal Chemistry
·
51
α-Fluoro-substituted thalidomide analogues
2003
·
Hon-Wah Man
, Laura G Corral
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
50
A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins.
2003
·
J Blake Marriott
, Ian A Clarke
, et al.
·
PubMed
·
50
Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion
1994
·
Donald S. Matteson
, Hon-Wah Man
·
The Journal of Organic Chemistry
·
47
Enantiotopic Differentiation of pro-R or pro-S Chlorides in (Dichloromethyl)borates by Chiral Lewis Acids: Enantioselective Synthesis of (α-Chloroalkyl)boronates
1997
·
Prabhakar K. Jadhav
, Hon-Wah Man
·
Journal of the American Chemical Society
·
38
Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors
1996
·
Prabhakar K Jadhav
, Hon-Wah Man
·
Tetrahedron Letters
·
38
High-precision asymmetric synthesis of stegobiol and stegobinone via boronic esters
1993
·
Donald S. Matteson
, Hon Wah Man
·
The Journal of Organic Chemistry
·
35
A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters
1999
·
Hon-Wah Man
, William C. Hiscox
, et al.
·
Organic Letters
·
33
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
2011
·
Alexander L. Ruchelman
, Hon-Wah Man
, et al.
·
Bioorganic & Medicinal Chemistry
·
28
Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition.
2003
·
Michael S Gee
, Sosina Makonnen
, et al.
·
PubMed
·
15
Effect of 3-Fluorothalidomide and 3-Methylthalidomide Enantiomers on Tumor Necrosis Factor Production and Antitumor Responses to the Antivascular Agent 5,6-Dimethylxanthenone-4-Acetic Acid (DMXAA)
2003
·
Francisco Chung
, Brian D. Palmer
, et al.
·
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
·
15
Direct Synthesis of [α-[(tert-Butoxycarbonyl)amino]alkyl]- boronates from (α-Haloalkyl)boronates
1996
·
Prabhakar K. Jadhav
, Hon-Wah Man
·
The Journal of Organic Chemistry
·
15
Antiproliferative Effects of CC-8062 and CC-8075 in Pancreatic Cancer Cells
2008
·
Petros X.E. Mouratidis
, Kay W. Colston
, et al.
·
Pancreas
·
14
Potent Inhibition of Cytokine Production from Intestinal Lamina Propria T Cells by Phosphodiesterase-4 Inhibitory Thalidomide Analogues
2001
·
John L. Prehn
, Carol Landers
, et al.
·
Journal of Clinical Immunology
·
11
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Works count:
39
Citation count:
3,054
H-index:
20
I10-index:
25
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