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Martina Metzler

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
1997 · Michael A. Kalchman, H. Brook Koide, et al. · Nature Genetics · 375
Complex asparagine‐linked oligosaccharides are required for morphogenic events during post‐implantation development.
1994 · M. Metzler, A. Gertz, et al. · The EMBO Journal · 335
The Influence of Huntingtin Protein Size on Nuclear Localization and Cellular Toxicity
1998 · Abigail S. Hackam, Roshni Singaraja, et al. · The Journal of Cell Biology · 326
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Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
2002 · François G. Gervais, Roshni Singaraja, et al. · Nature Cell Biology · 324
Huntingtin-Interacting Protein HIP14 Is a Palmitoyl Transferase Involved in Palmitoylation and Trafficking of Multiple Neuronal Proteins
2004 · Kun Huang, Anat Yanai, et al. · Neuron · 317
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HIP1 Functions in Clathrin-mediated Endocytosis through Binding to Clathrin and Adaptor Protein 2
2001 · Martina Metzler, Valérie Legendre-Guillemin, et al. · Journal of Biological Chemistry · 210
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Subtype‐Specific Enhancement of NMDA Receptor Currents by Mutant Huntingtin
1999 · Nansheng Chen, Tao Luo, et al. · Journal of Neurochemistry · 183
Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo
2005 · Simon C. Warby, Edmond Y. Chan, et al. · Human Molecular Genetics · 150
Als2 -deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities
2006 · R. S. Devon, P. C. Orban, et al. · Proceedings of the National Academy of Sciences · 148
Huntingtin Interacting Protein 1 Induces Apoptosis via a Novel Caspase-dependent Death Effector Domain
2000 · Abigail S. Hackam, Ayman S. Yassa, et al. · Journal of Biological Chemistry · 139
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking
2003 · Martina Metzler, Bo Li, et al. · The EMBO Journal · 125
Differential Susceptibility to Excitotoxic Stress in YAC128 Mouse Models of Huntington Disease between Initiation and Progression of Disease
2009 · Rona K. Graham, Mahmoud A. Pouladi, et al. · Journal of Neuroscience · 120
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HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
2014 · Barak Rotblat, Amber L. Southwell, et al. · Proceedings of the National Academy of Sciences · 117
Huntingtin Interacting Protein 1 (HIP1) Regulates Clathrin Assembly through Direct Binding to the Regulatory Region of the Clathrin Light Chain
2004 · Valerie Legendre-Guillemin, Martina Metzler, et al. · Journal of Biological Chemistry · 114
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HIP1 and HIP12 Display Differential Binding to F-actin, AP2, and Clathrin
2002 · Valerie Legendre-Guillemin, Martina Metzler, et al. · Journal of Biological Chemistry · 112
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Absence of Disease Phenotype and Intergenerational Stability of the Cag Repeat in Transgenic Mice Expressing the Human Huntington Disease Transcript
1996 · Y. P. Goldberg, M. A. Kalchman, et al. · Human Molecular Genetics · 111
Cleavage at the 586 Amino Acid Caspase-6 Site in Mutant huntingtin Influences Caspase-6 ActivationIn Vivo
2010 · Rona K. Graham, Yu Deng, et al. · Journal of Neuroscience · 110
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Hippi is essential for node cilia assembly and Sonic hedgehog signaling
2006 · Caroline Houde, Robin J. Dickinson, et al. · Developmental Biology · 106
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Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain
2006 · Jeremy M. Van Raamsdonk, Martina Metzler, et al. · Neurobiology of Disease · 100
Phosphorylation of Huntingtin at Ser421in YAC128 Neurons Is Associated with Protection of YAC128 Neurons from NMDA-Mediated Excitotoxicity and Is Modulated by PP1 and PP2A
2010 · Martina Metzler, Lu Gan, et al. · Journal of Neuroscience · 90
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Huntingtin-Interacting Protein 1 Influences Worm and Mouse Presynaptic Function and ProtectsCaenorhabditis elegansNeurons against Mutant Polyglutamine Toxicity
2007 · J. Alex Parker, Martina Metzler, et al. · Journal of Neuroscience · 70
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NMDA Receptor Function and NMDA Receptor-Dependent Phosphorylation of Huntingtin Is Altered by the Endocytic Protein HIP1
2007 · Martina Metzler, Lu Gan, et al. · Journal of Neuroscience · 46
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Life Without Huntingtin
1999 · Martina Metzler, Nansheng Chen, et al. · Journal of Neurochemistry · 45
HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin
2000 · Vikramjit S. Chopra, Martina Metzler, et al. · Mammalian Genome · 44
Huntingtin is required for normal hematopoiesis
2000 · M. Metzler · Human Molecular Genetics · 44
Works count: 35
Citation count: 3,996
H-index: 27
I10-index: 29
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