Author

Michael J. Ashton

Observed names: M J Ashton, M. ASHTON, M. J. ASHTON, M.J. Ashton, MICHAEL J. ASHTON

OpenAlex ID: A5110164890

Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogs

1994 · Michael J. Ashton, David C. Cook, et al. · Journal of Medicinal Chemistry · 112

Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP‐specific phosphodiesterase: comparison with rolipram

1995 · John E. Soilness, Christopher Maslen, et al. · British Journal of Pharmacology · 85

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New perspectives in lead generation II: Evaluating molecular diversity

1996 · Michael J. Ashton, Michael C. Jaye, et al. · Drug Discovery Today · 53

The absorption, metabolism and excretion of disodium cromoglycate in nine animal species

1973 · M.J. Ashton, B. Clark, et al. · Toxicology and Applied Pharmacology · 52

Anti-inflammatory 17β-Thioalkyl-16α,17α-ketal and -acetal Androstanes: A New Class of Airway Selective Steroids for the Treatment of Asthma

1996 · Michael J. Ashton, Christopher Lawrence, et al. · Journal of Medicinal Chemistry · 40

Acyl-CoA: cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT

1992 · Neil V. Harris, Andrew W. Bridge, et al. · Journal of Medicinal Chemistry · 39

RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT)

1992 · M.J. Ashton, A.W. Bridge, et al. · Bioorganic & Medicinal Chemistry Letters · 27

Heterocyclic analogs of chlorcyclizine with potent hypolipidemic activity

1984 · Michael J. Ashton, Alan Ashford, et al. · Journal of Medicinal Chemistry · 22

Synthesis of 6-Aryl-4-hydroxypiperidin-2-ones and a Possible Applications to the Synthesis of a Novel HMG-CoA Reductase Inhibitor

1989 · John B. Taylor, Michael J. Ashton, et al. · Heterocycles · 20

Acyl-CoA:CholesterolO-Acyltransferase (ACAT) Inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as Potent Inhibitors of ACAT

1996 · Peter C. Astles, Michael J. Ashton, et al. · Journal of Medicinal Chemistry · 17

RP 73163: A bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor

1996 · C. Smith, M.J. Ashton, et al. · Bioorganic & Medicinal Chemistry Letters · 12

New Low-Density Lipoprotein Receptor Upregulators Acting via a Novel Mechanism

1996 · Michael J. Ashton, Thomas J. Brown, et al. · Journal of Medicinal Chemistry · 9

New perspectives in lead generation I: Discovery of biological targets

1996 · Michael J. Ashton, Michael Jaye, et al. · Drug Discovery Today · 8

Anti-inflammatory Effects of Novel Selective Cyclic Nucleotide Phosphodiesterase Inhibitors

1993 · J.-A. KARLSSON, J. SOUNESS, et al. · Elsevier eBooks · 8

Microbiological hydroxylation. Part XIII. Cyclododecanone and cyclopentadecanone as substrates for steroid-hydroxylating fungi

1974 · Michael J. Ashton, A. Sydney Bailey, et al. · Journal of the Chemical Society Perkin Transactions 1 · 6

Microbiological hydroxylation. Part XII. Comparative behaviour of D-homogonane (perhydrochrysene) ketones and steroids

1974 · Michael J. Ashton, A. Sydney Bailey, et al. · Journal of the Chemical Society Perkin Transactions 1 · 5

Acylthioxanthenes: agents which selectively reduce decerebrate rigidity in the cat

1980 · Michael J. Ashton, Robert F. Chapman, et al. · Journal of Medicinal Chemistry · 4

ChemInform Abstract: Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3‐(Cyclopentyloxy)‐4‐ methoxybenzamides and Analogues.

1994 · M. J. ASHTON, D. C. COOK, et al. · ChemInform · 3

ChemInform Abstract: Antiinflammatory 17β‐Thioalkyl‐16α,17α‐ketal and ‐ acetal Androstanes: A New Class of Airway Selective Steroids for the Treatment of Asthma.

1997 · M. J. ASHTON, C. LAWRENCE, et al. · ChemInform · 2

HMG-CoA Reductase Inhibitors

1992 · M J Ashton, G Fenton · 1

ChemInform Abstract: New Low‐Density Lipoprotein Receptor Upregulators Acting via a Novel Mechanism.

1996 · M. J. ASHTON, T. J. BROWN, et al. · ChemInform

ChemInform Abstract: Acyl‐CoA:Cholesterol O‐Acyl Transferase (ACAT) Inhibitors. Part 1. 2‐( Alkylthio)‐4,5‐diphenyl‐1H‐imidazoles as Potent Inhibitors of ACAT.

1993 · N. V. HARRIS, C. SMITH, et al. · ChemInform

ChemInform Abstract: Synthesis of 6‐Aryl‐4‐hydroxypiperidin‐2‐ones and a Possible Application to the Synthesis of a Novel HMG‐CoA Reductase Inhibitor.

1989 · M. J. ASHTON, S. J. HILLS, et al. · ChemInform

ChemInform Abstract: HETEROCYCLIC ANALOGS OF CHLORCYCLIZINE WITH POTENT HYPOLIPIDEMIC ACTIVITY

1985 · M. J. ASHTON, A. ASHFORD, et al. · ChemInform

ChemInform Abstract: ACYLTHIOXANTHENES: AGENTS WHICH SELECTIVELY REDUCE DECEREBRATE RIGIDITY IN THE CAT

1980 · M. J. ASHTON, R. F. CHAPMAN, et al. · ChemInform

Works count: 27

Citation count: 525

H-index: 11

I10-index: 11