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Author

A. Shao

Observed name: Ada Shao
Observed institution: Roche (United States)
OpenAlex ID: A5110166955
3‑Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models
2012 · Michael Soth, Johannes C. Hermann, et al. · Journal of Medicinal Chemistry · 67
Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors
2013 · Saul Jaime-Figueroa, Javier De Vicente, et al. · Bioorganic & Medicinal Chemistry Letters · 34
Acoustic matrix microseeding: improving protein crystal growth with minimal chemical bias
2010 · Armando G. Villaseñor, April Wong, et al. · Acta Crystallographica Section D Biological Crystallography · 30
Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): Kinase profiling guided optimization of a 1,2,3-benzotriazole lead
2012 · Wylie S. Palmer, Muzaffar Alam, et al. · Bioorganic & Medicinal Chemistry Letters · 28
Nanolitre-scale crystallization using acoustic liquid-transfer technology
2012 · Armando G. Villaseñor, April Wong, et al. · Acta Crystallographica Section D Biological Crystallography · 25
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Scaffold hopping towards potent and selective JAK3 inhibitors: Discovery of novel C-5 substituted pyrrolopyrazines
2014 · Javier de Vicente, Remy Lemoine, et al. · Bioorganic & Medicinal Chemistry Letters · 21
Discovery of a novel series of 4-quinolone JNK inhibitors
2012 · Leyi Gong, Yun-Chou Tan, et al. · Bioorganic & Medicinal Chemistry Letters · 19
Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): Optimization for JNK potency and physicochemical properties
2013 · Leyi Gong, Xiaochun Han, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Crystal structure of JNK1 in complex with JIP1 peptide and 4-{4-[4-(4-Methanesulfonyl-piperidin-1-yl)-indol-1-yl]-pyrimidin-2-ylamino}-cyclohexan
2013 · A. Kuglstatter, A. Shao · Worldwide Protein Data Bank
JAK3 kinase domain in complex with 2-Phenoxy-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1-cyclopropyl-ethyl)-amide
2012 · A. Kuglstatter, A. Shao · Worldwide Protein Data Bank
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-2-hydroxy-1,2-dimethyl-propyl)-amide
2012 · A. Kuglstatter, A. Shao · Worldwide Protein Data Bank
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((R)-1-methyl-2-oxo-2-piperidin-1-yl-ethyl)-amide
2012 · A. Kuglstatter, A. Shao · Worldwide Protein Data Bank
Works count: 12
Citation count: 242
H-index: 8
I10-index: 8
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