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Austin Bautista
Observed name:
Bautista, Austin
Observed institutions:
Alberta Health Services,
University of Alberta
OpenAlex ID:
A5111089169
Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes
2020
·
Joan Camunas-Soler
, Xiao-Qing Dai
, et al.
·
Cell Metabolism
·
282
Cystic fibrosis–related diabetes is caused by islet loss and inflammation
2018
·
Nathaniel J. Hart
, Radhika Aramandla
, et al.
·
JCI Insight
·
183
PDF
Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells
2018
·
Soren K. Thomsen
, Anne Raimondo
, et al.
·
Nature Genetics
·
85
PDF
A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human β-Cells and Is Impaired in Type 2 Diabetes
2016
·
Richard Yan-Do
, Eric Duong
, et al.
·
Diabetes
·
84
Interleukin-1 signaling contributes to acute islet compensation
2016
·
Catherine Hajmrle
, Nancy Smith
, et al.
·
JCI Insight
·
83
PDF
Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress
2022
·
Shristi Shrestha
, Galina Erikson
, et al.
·
Science Advances
·
82
Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state
2022
·
Xiao-Qing Dai
, Joan Camunas-Soler
, et al.
·
Cell Metabolism
·
81
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk
2022
·
Antje K. Rottner
, Yingying Ye
, et al.
·
Nature Genetics
·
61
PDF
HumanIslets.com: Improving accessibility, integration, and usability of human research islet data
2024
·
Jessica D. Ewald
, Yao Lu
, et al.
·
Cell Metabolism
·
54
Autocrine activation of P2Y1 receptors couples Ca2+ influx to Ca2+ release in human pancreatic beta cells
2014
·
Shara Khan
, Richard Yan-Do
, et al.
·
Diabetologia
·
52
PDF
Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction
2017
·
Jianyang Fu
, Xiaoqing Dai
, et al.
·
Diabetes
·
51
PDF
Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance
2022
·
Søs Skovsø
, Evgeniy Panzhinskiy
, et al.
·
Nature Communications
·
48
PDF
A glucose-dependent spatial patterning of exocytosis in human β cells is disrupted in type 2 diabetes
2019
·
Jianyang Fu
, John Maringa Githaka
, et al.
·
JCI Insight
·
24
PDF
Antiaging Glycopeptide Protects Human Islets Against Tacrolimus-Related Injury and Facilitates Engraftment in Mice
2015
·
Boris L. Gala-Lopez
, Andrew R. Pepper
, et al.
·
Diabetes
·
22
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
2023
·
Katia K. Mattis
, Nicole A. J. Krentz
, et al.
·
Diabetologia
·
21
PDF
A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding
2024
·
Haopeng Lin
, Kunimasa Suzuki
, et al.
·
Nature Communications
·
19
PDF
A role for PKD1 in insulin secretion downstream of P2Y 1 receptor activation in mouse and human islets
2019
·
Shara Khan
, Mourad Ferdaoussi
, et al.
·
Physiological Reports
·
16
PDF
β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet–Fed Mice
2021
·
Haopeng Lin
, Nancy Smith
, et al.
·
Diabetes
·
15
PDF
RFX6 Maintains Gene Expression and Function of Adult Human Islet α-Cells
2023
·
Vy M.N. Coykendall
, Mollie F. Qian
, et al.
·
Diabetes
·
14
Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific
2019
·
Rafael Arrojo e Drigo
, Galina Erikson
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
14
PDF
Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes
2025
·
Theodore dos Santos
, Xiao Qing Dai
, et al.
·
Journal of Clinical Investigation
·
13
PDF
Cisplatin Exposure Dysregulates Insulin Secretion in Male and Female Mice
2025
·
Lahari Basu
, Lili Grieco-St-Pierre
, et al.
·
Diabetes
·
8
PDF
Isolation of Human Pancreatic Islets of Langerhans for Research v2
2019
·
James Lyon
, Aliya F Spigelman
, et al.
·
7
PDF
Isolation of Human Pancreatic Islets of Langerhans for Research v3
2021
·
James Lyon
, Aliya F Spigelman
, et al.
·
6
Improved glucose tolerance with DPPIV inhibition requires β‐cell SENP1 amplification of glucose‐stimulated insulin secretion
2020
·
Mourad Ferdaoussi
, Nancy Smith
, et al.
·
Physiological Reports
·
6
PDF
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Works count:
40
Citation count:
1,340
H-index:
16
I10-index:
21
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