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Takashi Nagaya

Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors.
1991 · V K Chatterjee, T Nagaya, et al. · Journal of Clinical Investigation · 196
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Nuclear Receptor Corepressors Activate Rather than Suppress Basal Transcription of Genes That Are Negatively Regulated by Thyroid Hormone
1997 · Tetsuya Tagami, Laird D. Madison, et al. · Molecular and Cellular Biology · 194
Inhibition of NF-κB Activity Decreases the VEGF mRNA Expression in MDA-MB-231 Breast Cancer Cells
2002 · Arihiro Shibata, Takashi Nagaya, et al. · Breast Cancer Research and Treatment · 168
Thyroid hormone receptor dimerization is required for dominant negative inhibition by mutations that cause thyroid hormone resistance
1993 · T. Nagaya, J.L. Jameson · Journal of Biological Chemistry · 143
Thyroid hormone receptor mutants that cause resistance to thyroid hormone. Evidence for receptor competition for DNA sequences in target genes.
1992 · T Nagaya, L.D. Madison, et al. · Journal of Biological Chemistry · 131
Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells.
1996 · M Sato, T Miyazaki, et al. · PubMed · 107
A potential role of activated NF-κB in the pathogenesis of euthyroid sick syndrome
2000 · Takashi Nagaya, Miyuki Fujieda, et al. · Journal of Clinical Investigation · 106
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Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor
1996 · R E Weiss, Y Hayashi, et al. · The Journal of Clinical Endocrinology & Metabolism · 106
Culture in Vector-Averaged Gravity Under Clinostat Rotation Results in Apoptosis of Osteoblastic ROS 17/2.8 Cells
2000 · Devanand Sarkar, Takashi Dr. Nagaya, et al. · Journal of Bone and Mineral Research · 94
Inhibition of nuclear factor-kappaB activation confers sensitivity to tumor necrosis factor-alpha by impairment of cell cycle progression in human glioma cells.
1999 · G Otsuka, T Nagaya, et al. · PubMed · 53
Distinct dimerization domains provide antagonist pathways for thyroid hormone receptor action.
1993 · T Nagaya, J.L. Jameson · Journal of Biological Chemistry · 52
Thyroid hormone resistance syndrome: correlation of dominant negative activity and location of mutations
1993 · T Nagaya, N L Eberhardt, et al. · The Journal of Clinical Endocrinology & Metabolism · 45
Activation of Transcriptionally Active Nuclear Factor- B by Tumor Necrosis Factor- and Its Inhibition by Antioxidants in Rat Thyroid FRTL-5 Cells
1998 · Toyone Kikumori, Fukushi Kambe, et al. · Endocrinology · 43
Pro-opiomelanocortin gene expression in silent corticotroph-cell adenoma and Cushing's disease
1990 · Takashi Nagaya, Hisao Seo, et al. · Journal of neurosurgery · 43
Functional properties of a novel mutant thyroid hormone receptor in a family with generalized thyroid hormone resistance syndrome
1992 · M. Adams, T. Nagaya, et al. · Clinical Endocrinology · 39
Detection of mRNA of prolactin and ACTH in clinically nonfunctioning pituitary adenomas
1988 · Tsuyoshi Sakurai, Hisao Seo, et al. · Journal of neurosurgery · 39
Glucocorticoids increase retinoid-X receptor alpha (RXRalpha) expression and enhance thyroid hormone action in primary cultured rat hepatocytes
1999 · S Yamaguchi, Y Murata, et al. · Journal of Molecular Endocrinology · 36
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Intracellular Proteolytic Cleavage of 9-cis-Retinoic Acid Receptor α by Cathepsin L-type Protease Is a Potential Mechanism for Modulating Thyroid Hormone Action
1998 · Takashi Nagaya, Yoshiharu Murata, et al. · Journal of Biological Chemistry · 35
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Inhibitory effects of cyclosporin A on calcium mobilization-dependent interleukin-8 expression and invasive potential of human glioblastoma U251MG cells
2004 · Kenichi Wakabayashi, Fukushi Kambe, et al. · Oncogene · 34
9-cis-Retinoic Acid Decreases the Level of Its Cognate Receptor, Retinoid X Receptor, through Acceleration of the Turnover
1999 · Yoshio Nomura, Takashi Nagaya, et al. · Biochemical and Biophysical Research Communications · 33
Expression of PPARγ and Its Ligand‐dependent Growth Inhibition in Human Brain Tumor Cell Lines
2002 · Mihoko Kato, Takashi Nagaya, et al. · Japanese Journal of Cancer Research · 31
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Requirement of Corepressor Binding of Thyroid Hormone Receptor Mutants for Dominant Negative Inhibition
1998 · Takashi Nagaya, Miyuki Fujieda, et al. · Biochemical and Biophysical Research Communications · 28
Cleavage of RXRα by a Lysosomal Enzyme, Cathepsin L-type Protease
1999 · Yoshio Nomura, Takashi Nagaya, et al. · Biochemical and Biophysical Research Communications · 27
Dominant Negative and DNA-Binding Properties of Mutant Thyroid Hormone Receptors That Are Defective in Homodimerization But Not Heterodimerization
1995 · KOICHI KITAJIMA, TAKASHI NAGAYA, et al. · Thyroid · 27
Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation
1996 · Y Nomura, T Nagaya, et al. · Endocrinology · 25
Works count: 68
Citation count: 2,060
H-index: 25
I10-index: 36
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