Get started
Author

Ann Beaumont

Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology.
1993 · B P Roques, F Noble, et al. · Pharmacological Reviews · 770
Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA.
1987 · A. Devault, C. Lazure, et al. · The EMBO Journal · 237
Biology of Opioid Peptides
1979 · A Beaumont, J Hughes · The Annual Review of Pharmacology and Toxicology · 186
Characterization of Glu350 as a Critical Residue Involved in the N-Terminal Amine Binding Site of Aminopeptidase N (EC 3.4.11.2): Insights into Its Mechanism of Action
1998 · Nathalie Luciani, Cynthia Marie-Claire, et al. · Biochemistry · 107
Neutral endopeptidase-24.11 inhibitors: from analgesics to antihypertensives?
1990 · Bernard P. Rogues, Ann Beaumont · Trends in Pharmacological Sciences · 101
Exploration of the catalytic site of endopeptidase 24.11 by site‐directed mutagenesis Histidine residues 583 and 587 are essential for catalysis
1988 · Alain Devault, Valérie Sales, et al. · FEBS Letters · 86
PDF
The Role of Histidine 231 in Thermolysin-like Enzymes.
1995 · Ann Beaumont, Michael J. O'Donohue, et al. · Journal of Biological Chemistry · 84
Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11).
1991 · A Beaumont, H Le Moual, et al. · Journal of Biological Chemistry · 65
The Roles of the Prosequence of Thermolysin in Enzyme Inhibition and Folding in Vitro
1996 · Michael J. O'Donohue, Ann Beaumont · Journal of Biological Chemistry · 63
PDF
The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli 1 1Edited by A. R. Fersht
1999 · Cynthia Marie-Claire, Emmanuel Ruffet, et al. · Journal of Molecular Biology · 62
A 94-kDa protein, identified as neutral endopeptidase-24.11, can inactivate atrial natriuretic peptide in the vascular endothelium.
1992 · J M Soleilhac, E Lucas, et al. · Molecular Pharmacology · 61
Intramolecular Processing of Prothermolysin
1998 · Cynthia Marie-Claire, Bernard P. Roques, et al. · Journal of Biological Chemistry · 50
PDF
Cloning and expression in Bacillus subtilis of the npr gene from Bacillus thermoproteolyticus Rokko coding for the thermostable metalloprotease thermolysin
1994 · M J O'Donohue, B P Roques, et al. · Biochemical Journal · 46
Evidence by Site-Directed Mutagenesis That Arginine 203 of Thermolysin and Arginine 717 of Neprilysin (Neutral Endopeptidase) Play Equivalent Critical Roles in Substrate Hydrolysis and Inhibitor Binding
1997 · Cynthia Marie-Claire, Emmanuel Ruffet, et al. · Biochemistry · 37
The use of a monoclonal antibody for the rapid purification of kidney neutral endopeptidase ("enkephalinase") solubilized in octyl glucoside
1987 · Muriel Aubry, Alfred Berteloot, et al. · Biochemistry and Cell Biology · 34
Opioid Peptides: Aspects of Their Origin, Release and Metabolism
1980 · J. Hughes, A. Beaumont, et al. · Journal of Experimental Biology · 32
Functional residues at the active site of aminopeptidase N
1991 · Armelle HELENE, Ann BEAUMONT, et al. · European Journal of Biochemistry · 29
Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11.
1992 · A Beaumont, B Barbe, et al. · Journal of Biological Chemistry · 27
New Thiol Inhibitors of Neutral Endopeptidase EC 3.4.24.11: Synthesis and Enzyme Active-Site Recognition
1994 · Isabel Gomez-Monterrey, Ann Beaumont, et al. · Journal of Medicinal Chemistry · 24
Development of [125I]RB104, a potent inhibitor of neutral endopeptidase 24.11, and its use in detecting nanogram quantities of the enzyme by "inhibitor gel electrophoresis".
1992 · M C Fournié-Zaluski, J M Soleilhac, et al. · Proceedings of the National Academy of Sciences · 23
Opioid peptide precursors in striatum
1980 · A. Beaumont, J.A. Fuentes, et al. · FEBS Letters · 22
PDF
Presence of a histidine at the active site of the neutral endopeptidase — 24.11
1986 · Ann Beaumont, Bernard P. Roques · Biochemical and Biophysical Research Communications · 21
Neutral endopeptidase 24.11 and angiotensin converting enzyme like activity in calla positive and calla negative lymphoid cells
1989 · A. Beaumont, J.C. Brouet, et al. · Biochemical and Biophysical Research Communications · 19
Peptidase Inactivation of Enkephalins: Design of Inhibitors and Biochemical, Pharmacological, and Clinical Applications
1993 · B. P. Roques, A. Beaumont, et al. · Handbook of experimental pharmacology · 13
Neurotensin high affinity binding sites and endopeptidase 24.11 are present respectively in the meningothelial and in the fibroblastic components of human meningiomas
1990 · Pierre Mailleux, Serge Przedborski, et al. · Peptides · 13
Works count: 40
Citation count: 2,275
H-index: 21
I10-index: 26
Year
Topic
Type