Author

Jack L. Valentine

Observed names: J L Valentine, J. L. Valentine, J. Valentine, J.L. Valentine, Jack Valentine

Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)

Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Arkansas Children's Hospital, RTI International, Princeton University, Bristol-Myers Squibb (United States), University of Arkansas for Medical Sciences

OpenAlex ID: A5111383017

Aprepitant in adolescent patients for prevention of chemotherapy‐induced nausea and vomiting: A randomized, double‐blind, placebo‐controlled study of efficacy and tolerability

2008 · Lia Gore, Sant Chawla, et al. · Pediatric Blood & Cancer · 96

Antiphencyclidine monoclonal antibody therapy significantly changes phencyclidine concentrations in brain and other tissues in rats.

1996 · J L Valentine, S M Owens · Journal of Pharmacology and Experimental Therapeutics · 67

Antiphencyclidine monoclonal Fab fragments reverse phencyclidine-induced behavioral effects and ataxia in rats.

1996 · J L Valentine, M Mayersohn, et al. · Journal of Pharmacology and Experimental Therapeutics · 45

Anti-phencyclidine monoclonal Fab fragments markedly alter phencyclidine pharmacokinetics in rats.

1994 · J L Valentine, L W Arnold, et al. · Journal of Pharmacology and Experimental Therapeutics · 43

Metabolism and disposition of 1-bromopropane in rats and mice following inhalation or intravenous administration

2006 · C.E. Garner, S.C.J. Sumner, et al. · Toxicology and Applied Pharmacology · 42

Evaluating and Defining Sample Preparation Procedures for DBS LC–MS/MS Assays

2010 · Guowen Liu, Laura Patrone, et al. · Bioanalysis · 41

Disposition of a monoclonal anti-phencyclidine Fab fragment of immunoglobulin G in rats.

1993 · M B McClurkan, J L Valentine, et al. · Journal of Pharmacology and Experimental Therapeutics · 37

Pharmacokinetics of Oral Dexamethasone and Midazolam When Administered With Single-Dose Intravenous 150 mg Fosaprepitant in Healthy Adult Subjects

2011 · Thomas C. Marbury, Phung L. Ngo, et al. · The Journal of Clinical Pharmacology · 33

Initial observations of rabbit retinal pigment epithelium-choroid-sclera preparations.

1988 · D A Frambach, J L Valentine, et al. · PubMed · 31

A Convenient Strategy for Quantitative Determination of Drug Concentrations in Tissue Homogenates Using a Liquid Chromatography/Tandem Mass Spectrometry Assay for Plasma Samples

2011 · Hao Jiang, Jianing Zeng, et al. · Analytical Chemistry · 27

A validated LC–MS/MS method for the simultaneous determination of BMS-791325, a hepatitis C virus NS5B RNA polymerase inhibitor, and its metabolite in plasma

2014 · Long Yuan, Hao Jiang, et al. · Journal of Chromatography B · 20

Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium.

1988 · D A Frambach, J L Valentine, et al. · PubMed · 20

Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and without aprepitant

2010 · S. Aubrey Stoch, Cynthia Gargano, et al. · Cancer Chemotherapy and Pharmacology · 19

Gestational exposure to cocaine or pharmacologically related compounds: Effects on behavior and striatal dopamine receptors

1998 · Christopher W. Stewart, Frank M. Scalzo, et al. · Life Sciences · 17

Dextromethorphan in nonketotic hyperglycinaemia: metabolic variation confounds the dose‐response relationship

1997 · G. L. Arnold, M. L. Griebel, et al. · Journal of Inherited Metabolic Disease · 17

Dose- and time-dependent changes in phencyclidine metabolite covalent binding in rats and the possible role of CYP2D1.

1993 · S M Owens, M Gunnell, et al. · Journal of Pharmacology and Experimental Therapeutics · 15

Effects of LRRK2 Inhibitors in Nonhuman Primates

2023 · Glen K. Miller, Sabu Kuruvilla, et al. · Toxicologic Pathology · 11

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Furosemide-sensitive Cl transport in bovine retinal pigment epithelium.

1989 · D A Frambach, J L Valentine, et al. · PubMed · 11

937 Safety, Tolerability, and Pharmacokinetics After Single and Multiple Doses of Mk-3281 in Healthy Subjects

2009 · D. Brainard, D.H. Wright, et al. · Journal of Hepatology · 10

Toxic effects of cocaine to the cardiovascular system in conscious and anesthetized rats and rabbits: evidence for a direct effect on the myocardium.

1990 · H M Rhee, J L Valentine, et al. · PubMed · 10

Topical phenylephrine for mydriasis affects rabbit retinal pigment epithelial transport.

1989 · D A Frambach, J L Valentine, et al. · PubMed · 5

Effect of Aprepitant 40 mg on Cyto - chrome P-450 2C9 Activity: A Random- ized, Double-Blind, Placebo-Controlled, Parallel-Group Study in Healthy Young Adults

2009 · Phung L. Ngo, Craig R. Shadle, et al. · 2

Cardiovascular effects of tropacocaine in conscious and anesthetized rabbits: lack of evidence for neuro-cardiac interactions and acute neurotoxicity.

1995 · H M Rhee, S Y Lee, et al. · PubMed · 2

Aprepitant for the prevention of chemotherapy‐induced nausea and vomiting in adolescents: Response

2009 · Lia Gore, Sant Chawla, et al. · Pediatric Blood & Cancer · 1

The Application of ADME Principles in Pharmaceutical Safety Assessment

2010 · J.L. Valentine, W.C. Shyu, et al. · Elsevier eBooks

Works count: 25

Citation count: 622

H-index: 15

I10-index: 20