Author

Ming Wu Chou

Observed names: M W Chou, M. Chou, M. W. CHOU, M. W. Chou, M.W. Chou, MING W. CHOU, Ming W. Chou, Ming Chou, Ming W Chou, Ming W. Chou

Observed institutions: United States Department of Health and Human Services, National Institutes of Health, National Center for Toxicological Research, United States Food and Drug Administration, Uniformed Services University of the Health Sciences, University of Pittsburgh, Chinese University of Hong Kong, United States Public Health Service, National Institute of Environmental Health Sciences, UPMC Hillman Cancer Center, Instituto Superior Técnico, Rutgers New Jersey Medical School, Centro de Química Estrutural, Universidade Técnica de Lisboa

OpenAlex ID: A5111483349

Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms

2004 · Peter P. Fu, Qingsu Xia, et al. · Drug Metabolism Reviews · 582

Pyrrolizidine alkaloids - Tumorigenic components in Chinese herbal medicines and dietary supplements

2020 · P.P. Fu, Y.-C. Yang, et al. · Journal of Food and Drug Analysis · 142

The orientation of the nitro substituent predicts the direct-acting bacterial mutagenicity of nitrated polycyclic aromatic hydrocarbons

1985 · Peter P. Fu, Ming W. Chou, et al. · Mutation Research Letters · 110

Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine

2003 · Ming W. Chou, Yu-Ping Wang, et al. · Toxicology Letters · 105

Metabolic Activation of the Tumorigenic Pyrrolizidine Alkaloid, Riddelliine, Leading to DNA Adduct Formation in Vivo

2000 · Ya-Chen Yang, Jian Yan, et al. · Chemical Research in Toxicology · 104

Comparison of DNA adduct levels associated with oxidative stress in human pancreas

1998 · F.F. Kadlubar, K.E. Anderson, et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 101

Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid

2004 · Yu-Ping Wang, Jian Yan, et al. · Toxicology Letters · 97

Genotoxic Pyrrolizidine Alkaloids — Mechanisms Leading to DNA Adduct Formation and Tumorigenicity

2002 · Peter P. Fu, Qingsu Xia, et al. · International Journal of Molecular Sciences · 90

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Genotoxic Pyrrolizidine Alkaloids and Pyrrolizidine Alkaloidn-oxides—mechanisms Leading to Dna Adduct Formation and Tumorigenicity

2001 · P. P. Fu, M. W. Chou, et al. · Journal of Environmental Science and Health Part C · 81

Human Liver Microsomal Metabolism and DNA Adduct Formation of the Tumorigenic Pyrrolizidine Alkaloid, Riddelliine

2002 · Qingsu Xia, Ming W. Chou, et al. · Chemical Research in Toxicology · 80

Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo

2004 · Yu-Ping Wang, Jian Yan, et al. · Cancer Letters · 69

Mutagenicity and toxicity studies of p-phenylenediamine and its derivatives

1995 · King-Thom Chung, Chris A. Murdock, et al. · Toxicology Letters · 69

High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Pyrrolizidine Alkaloid-Derived DNA Adducts in Vitro and in Vivo

2010 · Peter P. Fu, Ming W. Chou, et al. · Chemical Research in Toxicology · 67

Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives.

1980 · P G Wislocki, K M Gadek, et al. · PubMed · 62

Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine

2005 · Qingsu Xia, Ming W. Chou, et al. · Cancer Letters · 58

Metabolism of the mutagenic environmental pollutant, 6-nitrobenzo[a]pyrene: Metabolic activation via ring oxidation

1982 · P.P. Fu, M.W. Chou, et al. · Biochemical and Biophysical Research Communications · 57

Metabolic Formation of DHP-Derived DNA Adducts from a Representative Otonecine Type Pyrrolizidine Alkaloid Clivorine and the Extract of Ligularia hodgsonnii Hook

2004 · Qingsu Xia, Ming W. Chou, et al. · Chemical Research in Toxicology · 52

Metabolic Activation of the Tumorigenic Pyrrolizidine Alkaloid, Retrorsine, Leading to DNA Adduct Formation In Vivo

2005 · Yu-Ping Wang, Peter P. Fu, et al. · International Journal of Environmental Research and Public Health · 51

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Identification of DNA Adducts Derived from Riddelliine, a Carcinogenic Pyrrolizidine Alkaloid

2003 · Ming W. Chou, Yan Jian, et al. · Chemical Research in Toxicology · 50

Combined reversed-phase and normal-phase high-performance liquid chromatography in the purification and identification of 7,12-dimethylbenz[a]anthrace metabolites.

1979 · Ming W. Chou, Shen K. Yang · Journal of Chromatography A · 48

Formation of DHP-derived DNA adducts in vivo from dietary supplements and Chinese herbal plant extracts containing carcinogenic pyrrolizidine alkaloids

2006 · Ming W Chou, Peter P Fu · Toxicology and Industrial Health · 47

Development of a 32P-Postlabeling/HPLC Method for Detection of Dehydroretronecine-Derived DNA Adducts in Vivo and in Vitro

2000 · Ya-Chen Yang, Jian Yan, et al. · Chemical Research in Toxicology · 46

Identification of 7,12-dimethylbenz[ a ]anthracene metabolites that lead to mutagenesis in mammalian cells

1979 · Eliezer Huberman, Ming W. Chou, et al. · Proceedings of the National Academy of Sciences · 44

Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine

2008 · Qingsu Xia, Jian Yan, et al. · Toxicology Letters · 41

Identification of four trans-3,4-dihydrodiol metabolites of 7,12-dimethylbenz[a]anthracene and their in vitro DNA-binding activities upon further metabolism.

1978 · M W Chou, S K Yang · Proceedings of the National Academy of Sciences · 41

Works count: 112

Citation count: 3,395

H-index: 31

I10-index: 74