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Jagabandhu Das

Discovery of N -(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays
2004 · Louis J. Lombardo, Francis Y. Lee, et al. · Journal of Medicinal Chemistry · 1,322
2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan -Src Kinase Inhibitor
2006 · Jagabandhu Das, Ping Chen, et al. · Journal of Medicinal Chemistry · 403
Total synthesis of (.+-.)-aphidicolin
1980 · E. J. Corey, Marcus A. Tius, et al. · Journal of the American Chemical Society · 130
Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation
2004 · Tai-An Lin, Kim W. McIntyre, et al. · Biochemistry · 112
Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors
2003 · Jagabandhu Das, Robert V. Moquin, et al. · Bioorganic & Medicinal Chemistry Letters · 108
Thrombin active site inhibitors
1995 · Jagabandhu Das, S. David Kimball · Bioorganic & Medicinal Chemistry · 94
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
2006 · Jagabandhu Das, Joseph A. Furch, et al. · Bioorganic & Medicinal Chemistry Letters · 74
Benzazepinone calcium channel blockers. 2. Structure activity and drug metabolism studies leading to potent antihypertensive agents. Comparison with benzothiazepinones
1992 · David M. Floyd, S. David Kimball, et al. · Journal of Medicinal Chemistry · 68
Total synthesis of the complement inhibitor K-76 in racemic form. Structural assignment to "K-76 monocarboxylic acid"
1982 · E. J. Corey, Jagabandhu Das · Journal of the American Chemical Society · 67
Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117
2003 · Jagabandhu Das, James Lin, et al. · Bioorganic & Medicinal Chemistry Letters · 61
Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck
2003 · John Wityak, Jagabandhu Das, et al. · Bioorganic & Medicinal Chemistry Letters · 58
Total synthesis of (.+-.)-stemodin and (.+-.)-stemodinone
1980 · E. J. Corey, Marcus A. Tius, et al. · Journal of the American Chemical Society · 56
Total synthesis of steroids. Part 1. Ring A aromatic compounds. Regiocontrol in diene additions with 6-methoxy-1-vinyl-3,4-dihydronaphthalene
1979 · Jagabandhu Das, Rudolf Kubela, et al. · Canadian Journal of Chemistry · 55
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Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors
2008 · Jagabandhu Das, Robert V. Moquin, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site
1992 · S. David Kimball, David M. Floyd, et al. · Journal of Medicinal Chemistry · 44
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors
2006 · Jagabandhu Das, Chunjian Liu, et al. · Bioorganic & Medicinal Chemistry Letters · 38
Crystallographic determination of the structures of human α‐thrombin complexed with BMS‐186282 and BMS‐189090
1996 · Mary F. Malley, John S. Sack, et al. · Protein Science · 35
Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors
2004 · Ping Chen, Derek Norris, et al. · Bioorganic & Medicinal Chemistry Letters · 33
Discovery of highly potent, selective, covalent inhibitors of JAK3
2017 · James Kempson, Damaso Ovalle, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Novel methods for syntheses of substituted oxazoles by cyclization of vinyl bromides
1992 · Jagabandhu Das, Joyce A. Reid, et al. · Tetrahedron Letters · 32
A new method for stereospecific cis hydroxylation of olefins
1982 · E.J. Corey, Jagabandhu Das · Tetrahedron Letters · 31
Novel Tricyclic Inhibitors of IκB Kinase
2009 · James Kempson, Steven H. Spergel, et al. · Journal of Medicinal Chemistry · 27
Dual metalloprotease inhibitors. IV. Utilization of thiazepines and thiazines as constrained peptidomimetic surrogates in mercaptoacyl dipeptides
1994 · Jagabandhu Das, Jeffrey A. Robl, et al. · Bioorganic & Medicinal Chemistry Letters · 22
7-Oxabicyclo[2.2.1]heptyl carboxylic acids as thromboxane A2 antagonists: aza .omega.-chain analogs
1990 · Masami Nakane, Joyce A. Reid, et al. · Journal of Medicinal Chemistry · 22
5-Amino-pyrazoles as potent and selective p38α inhibitors
2010 · Jagabandhu Das, Robert V. Moquin, et al. · Bioorganic & Medicinal Chemistry Letters · 21
Works count: 54
Citation count: 3,216
H-index: 22
I10-index: 37
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