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Laurent Ruel

Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
1996 · Vuk Stambolic, Laurent Ruel, et al. · Current Biology · 1,329
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Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
1996 · Pascal Heitzler, Marc Bourouis, et al. · Development · 348
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin,a component of the presenilin protein complex
1999 · M. Nishimura, G. Yu, et al. · Nature Medicine · 221
Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch
1993 · Laurent Ruel, Marc Bourouis, et al. · Nature · 202
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
2003 · Laurent Ruel, Ralph Rodriguez, et al. · Nature Cell Biology · 201
The conserved PI3′K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
2000 · Sam E Scanga, Laurent Ruel, et al. · Oncogene · 200
Cholesterol Modification of Hedgehog Is Required for Trafficking and Movement, Revealing an Asymmetric Cellular Response to Hedgehog
2003 · Armel Gallet, Ralph Rodriguez, et al. · Developmental Cell · 196
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Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog inDrosophilaepithelia
2006 · Armel Gallet, Laurent Ruel, et al. · Development · 177
An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2+ subfamily.
1990 · M. Bourouis, P. Moore, et al. · The EMBO Journal · 149
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Genetic analysis of protein kinase B (AKT) in Drosophila
1998 · Brian E. Staveley, Laurent Ruel, et al. · Current Biology · 141
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Regulation of the Protein Kinase Activity of ShaggyZeste-white3 by Components of the Wingless Pathway in Drosophila Cells and Embryos
1999 · Laurent Ruel, Vuk Stambolic, et al. · Journal of Biological Chemistry · 84
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Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila.
1993 · L. Ruel, V. Pantesco, et al. · The EMBO Journal · 68
Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling
2007 · Laurent Ruel, Armel Gallet, et al. · Development · 65
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Microvilli-derived extracellular vesicles carry Hedgehog morphogenic signals for Drosophila wing imaginal disc development
2021 · Ilse Hurbain, Anne-Sophie Macé, et al. · Current Biology · 45
Distinct Phosphorylations on Kinesin Costal-2 Mediate Differential Hedgehog Signaling Strength
2012 · Nadia Ranieri, Laurent Ruel, et al. · Developmental Cell · 38
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Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex
2014 · Nadia Ranieri, Pascal P. Thérond, et al. · Nature Communications · 31
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Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli: Figure 1.
2009 · Laurent Ruel, Pascal P. Thérond · Genes & Development · 23
Human Receptors Patched and Smoothened Partially Transduce Hedgehog Signal When Expressed in Drosophila Cells
2006 · Matthieu De Rivoyre, Laurent Ruel, et al. · Journal of Biological Chemistry · 23
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A Genome-Wide RNAi Screen Identifies Regulators of Cholesterol-Modified Hedgehog Secretion in Drosophila
2012 · Reid Aikin, Alexandra Cervantes, et al. · PLoS ONE · 18
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Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling
2010 · S. Raisin, L. Ruel, et al. · Developmental Biology · 17
Human receptor Smoothened, a mediator of Hedgehog signalling, expressed in its native conformation in yeast
2005 · Matthieu De Rivoyre, Frédéric Bonino, et al. · FEBS Letters · 14
A dual role for the protein kinase shaggy in the repression of achaete- scute
1993 · Pat Simpson, Laurent Ruel, et al. · Development · 13
Delta, Notch, and shaggy: Elements of a Lateral Signaling Pathway in Drosophila
1992 · P. Simpson, M. Bourouis, et al. · Cold Spring Harbor Symposia on Quantitative Biology · 13
Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila
2009 · Katie L. Ayers, Ralph Rodriguez, et al. · Developmental Biology · 6
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Mouse myodulin, a new potential angiogenic factor, functionally expressed in yeast
2005 · Didier F. Pisani, Matthieu De Rivoyre, et al. · Biochemical and Biophysical Research Communications · 5
Works count: 31
Citation count: 3,632
H-index: 18
I10-index: 23
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