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Ralph T. Mosley

Observed names: Mosley, R.T., R. T. MOSLEY, R. T. Mosley, R.T. Mosley, Ralph T Mosley
OpenAlex ID: A5111570535
Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry
1998 · Susan P. Rohrer, Elizabeth T. Birzin, et al. · Science · 457
Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase
2011 · Michael J. Sofia, Wonsuk Chang, et al. · Journal of Medicinal Chemistry · 276
Chemical Similarity Using Physiochemical Property Descriptors
1996 · Simon K. Kearsley, Susan Sallamack, et al. · Journal of Chemical Information and Computer Sciences · 267
Design and Pharmacology of N-[(3R)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist
2002 · Iyassu K. Sebhat, William J. Martin, et al. · Journal of Medicinal Chemistry · 194
Structure and Chemistry of Apicidins, a Class of Novel Cyclic Tetrapeptides without a Terminal α-Keto Epoxide as Inhibitors of Histone Deacetylase with Potent Antiprotozoal Activities
2002 · Sheo B. Singh, Deborah L. Zink, et al. · The Journal of Organic Chemistry · 151
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2
1998 · Lihu Yang, Scott C. Berk, et al. · Proceedings of the National Academy of Sciences · 128
Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
2012 · Ralph T. Mosley, Thomas E. Edwards, et al. · Journal of Virology · 121
Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor α Modulators
2004 · Seongkon Kim, Jane Y. Wu, et al. · Journal of Medicinal Chemistry · 102
Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors
1998 · M. R. Tota, T. S. Smith, et al. · Biochemistry · 98
Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of ras farnesyl-protein transferase
1993 · Sheo B. Singh, Deborah L. Zink, et al. · Tetrahedron · 95
Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach
2006 · Y.-D. Gao, S. H. Olson, et al. · Xenobiotica · 82
The Differential Interactions of Peroxisome Proliferator-Activated Receptor γ Ligands with Tyr473 Is a Physical Basis for Their Unique Biological Activities
2007 · Monica Einstein, Taro E. Akiyama, et al. · Molecular Pharmacology · 76
Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERα
2007 · Kevin D. Dykstra, Liangqin Guo, et al. · Bioorganic & Medicinal Chemistry Letters · 69
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics
2012 · Wonsuk Chang, Ralph T. Mosley, et al. · Bioorganic & Medicinal Chemistry Letters · 67
Benzimidazolones: A New Class of Selective Peroxisome Proliferator-Activated Receptor γ (PPARγ) Modulators
2011 · Weiguo Liu, Fiona Lau, et al. · Journal of Medicinal Chemistry · 59
Discovery of a Novel Class of Potent HCV NS4B Inhibitors: SAR Studies on Piperazinone Derivatives
2014 · Ramesh Kakarla, Jian Liu, et al. · Journal of Medicinal Chemistry · 54
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity
2004 · Helen Y. Chen, Kevin D. Dykstra, et al. · Bioorganic & Medicinal Chemistry Letters · 52
Determination of the relative and absolute stereochemistry of sphingofungins A, B, C, and D
1992 · VanMiddlesworth Frank, Claude Dufresne, et al. · Tetrahedron Letters · 51
Phenylpropenamide derivatives: Anti-hepatitis B virus activity of the Z isomer, SAR and the search for novel analogs
2011 · Peiyuan Wang, Devan Naduthambi, et al. · Bioorganic & Medicinal Chemistry Letters · 45
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
2007 · Christopher L. Hamblett, Joey L. Methot, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Amino acid substitution of arginine 80 in 17β-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics
2002 · Brian M McKeever, Barton K Hawkins, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 44
Use of 2′-Spirocyclic Ethers in HCV Nucleoside Design
2013 · Jinfa Du, Byoung-Kwon Chun, et al. · Journal of Medicinal Chemistry · 43
The discovery of tetrahydrofluorenones as a new class of estrogen receptor β-subtype selective ligands
2006 · R.R. Wilkening, R.W. Ratcliffe, et al. · Bioorganic & Medicinal Chemistry Letters · 43
Adenosine Deaminase-like Protein 1 (ADAL1): Characterization and Substrate Specificity in the Hydrolysis of N6- or O6-Substituted Purine or 2-Aminopurine Nucleoside Monophosphates
2011 · Eisuke Murakami, Haiying Bao, et al. · Journal of Medicinal Chemistry · 40
Estrogen receptor ligands. Part 11: Synthesis and activity of isochromans and isothiochromans
2004 · Jian Liu, Elizabeth T. Birzin, et al. · Bioorganic & Medicinal Chemistry Letters · 40
Works count: 63
Citation count: 3,140
H-index: 31
I10-index: 44
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