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Edwin R. Speck

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
2005 · Rukhsana Aslam, Edwin R. Speck, et al. · Blood · 499
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A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
2009 · Leola Chow, Rukhsana Aslam, et al. · Blood · 218
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Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets
2007 · John W. Semple, Rukhsana Aslam, et al. · Blood · 148
Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets
2017 · Anne Zufferey, Edwin R. Speck, et al. · Blood Advances · 136
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T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10
2017 · Rick Kapur, Michael Kim, et al. · Blood · 123
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Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia
2012 · Rukhsana Aslam, Yu Hu, et al. · Blood · 116
Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation.
1993 · M J Rapoport, A H Lazarus, et al. · The Journal of Experimental Medicine · 94
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DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis
2016 · Hajera Amatullah, Yuexin Shan, et al. · American Journal of Respiratory and Critical Care Medicine · 88
Transfusion‐related immunomodulation by platelets is dependent on their expression of MHC Class I molecules and is independent of white cells
2008 · Rukhsana Aslam, Edwin R. Speck, et al. · Transfusion · 84
Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury
2018 · Rick Kapur, Michael Kim, et al. · Blood Advances · 65
CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell–mediated immune thrombocytopenia
2015 · Li Guo, Rick Kapur, et al. · Blood · 65
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Indirect allorecognition of platelets by T helper cells during platelet transfusions correlates with anti-major histocompatibility complex antibody and cytotoxic T lymphocyte formation [published erratum appears in Blood 1995 Dec 15;86(12):4710]
1995 · JW Semple, ER Speck, et al. · Blood · 58
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Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)
2019 · Rick Kapur, Rukhsana Aslam, et al. · Platelets · 55
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Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury
2010 · Yoke Lin Fung, Michael Kim, et al. · Blood · 53
Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens
2000 · K. W. Annie Bang, Edwin R. Speck, et al. · Blood · 49
Extreme Leukoreduction of Major Histocompatibility Complex Class II Positive B Cells Enhances Allogeneic Platelet Immunity
1999 · John W. Semple, Edwin R. Speck, et al. · Blood · 48
IgG antiplatelet immunity is dependent on an early innate natural killer cell–derived interferon-γ response that is regulated by CD8+ T cells
2003 · Ebrahim Sayeh, Katherine Sterling, et al. · Blood · 43
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Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia
2013 · Li Guo, Lei Yang, et al. · Blood · 33
Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase
1996 · A Bang, ER Speck, et al. · Blood · 28
Antiplatelet antibody‐induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia
2018 · L. Guo, R. Kapur, et al. · Scandinavian Journal of Immunology · 22
Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells
2007 · Rukhsana Aslam, Michael Kim, et al. · Transfusion · 20
Immune responsiveness against allogeneic platelet transfusions is determined by the recipient's major histocompatibility complex class II phenotype
2004 · Ebrahim Sayeh, Rukshana Aslam, et al. · Transfusion · 18
Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets
2007 · Mimi Kjaersgaard, Rukhsana Aslam, et al. · Blood · 16
Evaluation of Platelet Gel Characteristics Using Thrombin Produced by the Thrombin Processing Device: A Comparative Study
2008 · Elisabeth Semple, Edwin R. Speck, et al. · Journal of Oral and Maxillofacial Surgery · 15
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia ( ITP )
2017 · Rick Kapur, Michelle D. Catalina, et al. · British Journal of Haematology · 14
Works count: 52
Citation count: 2,154
H-index: 20
I10-index: 26
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