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Anwar Murtaza

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
2007 · Chengbin Wu, Hua Ying, et al. · Nature Biotechnology · 346
A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens
1997 · Lindsay B. Nicholson, Anwar Murtaza, et al. · Proceedings of the National Academy of Sciences · 158
Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
2021 · Dan You, Stephen Hillerman, et al. · Journal for ImmunoTherapy of Cancer · 87
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Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1
2021 · Andrew P. Degnan, Godwin K. Kumi, et al. · ACS Medicinal Chemistry Letters · 70
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Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance
2019 · Jinqi Liu, Joshua Curtin, et al. · PLoS ONE · 67
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The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity
2009 · Philip D Bardwell, Jijie Gu, et al. · The Journal of Immunology · 67
Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands
1999 · Anwar Murtaza, Vijay K. Kuchroo, et al. · International Immunology · 41
Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists
2011 · Jinhe Li, Suzanne L. Mathieu, et al. · Journal of Neuroimmunology · 35
Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent
2020 · Upender Velaparthi, Chetan Padmakar Darne, et al. · ACS Medicinal Chemistry Letters · 31
Abstract 5709: PF-07104091, a first-in-class CDK2-selective inhibitor for the treatment of HR+/HER2- breast cancer and CCNE1high ovarian cancer
2024 · Chen Shen, Ming Qiu, et al. · Cancer Research · 21
Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors
2015 · Michael Friedman, Kristine E. Frank, et al. · Bioorganic & Medicinal Chemistry Letters · 19
Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists
2020 · Lalgudi S. Harikrishnan, Patrice Gill, et al. · Bioorganic & Medicinal Chemistry Letters · 14
Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis
2014 · Kalyan Chakravarthy, Robert Faltus, et al. · BMC Musculoskeletal Disorders · 14
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Self-Tolerance and the Composition of T Cell Repertoire
2000 · Linda A. Sherman, David J. Morgan, et al. · Immunologic Research · 14
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology
2024 · Liqi He, Meng Yao Zhang, et al. · ACS Medicinal Chemistry Letters · 8
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Abstract 3760: Preclinical antitumor activity of a CC chemokine receptor (CCR) 2/5 dual antagonist as monotherapy and in combination with immune checkpoint blockade
2018 · Qihong Zhao, Anwar Murtaza, et al. · Cancer Research · 8
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology
2024 · Yam B. Poudel, Liqi He, et al. · ACS Medicinal Chemistry Letters · 7
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Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor
2021 · Yong Zhang, Karen E. Parrish, et al. · Journal of Medicinal Chemistry · 7
Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL)
2024 · Rebecca A. Gallego, Stephanie Scales, et al. · Journal of Medicinal Chemistry · 6
Altered functional and biochemical response by CD8+ T cells that remain after tolerance
2001 · Anwar Murtaza, C. Thomas Nugent, et al. · International Immunology · 6
Abstract 595: Preclinical development of the CDK4 selective inhibitor PF-07220060: Increased CDK4 versus CDK6 inhibition leads to improved anti-tumor efficacy at therapeutic concentrations
2024 · Lars Anders, Bernadette Pascual, et al. · Cancer Research · 3
Pharmacodynamics‐based approach for efficacious human dose projection of BMS‐986260, a small molecule transforming growth factor beta receptor 1 inhibitor
2020 · Karen E. Parrish, Jesse Swanson, et al. · Biopharmaceutics & Drug Disposition · 3
The Role of Cytokines in Leprosy
2015 · Indira Nath, Anwar Murtaza, et al. · KARGER eBooks · 2
Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as Revealed by subtype selective agonists
2009 · Jinhe Li, Suzanne L. Mathieu, et al. · Biochemical Pharmacology · 2
Abstract 5903: MASTL small-molecule inhibition to target mitosis for cancer therapy
2024 · Chad M. Toledo, Koleen J. Eisele, et al. · Cancer Research
Works count: 30
Citation count: 1,036
H-index: 14
I10-index: 14
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