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Romuald Corbau

Observed names: Corbau, Romuald, R Corbau, R. Corbau, Romuald G Corbau
Observed institutions: Children's Hospital of Philadelphia, Inserm, German Cancer Research Center, Pfizer (United Kingdom), Spark Therapeutics (United States), Ashwell Museum, KU Leuven
OpenAlex ID: A5111646887
Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus
2007 · Dimitri Lavillette, Eve-Isabelle Pécheur, et al. · Journal of Virology · 212
Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate
2009 · Charles E. Mowbray, Catherine Burt, et al. · Bioorganic & Medicinal Chemistry Letters · 105
Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1
2010 · Romuald Corbau, Julie Mori, et al. · Antimicrobial Agents and Chemotherapy · 62
RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1
2016 · Megan S. Keiser, Alejandro Mas Monteys, et al. · Annals of Neurology · 58
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Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays
2009 · Lyn H. Jones, Gill Allan, et al. · Journal of Medicinal Chemistry · 56
Biochemical Activities of Minute Virus of Mice Nonstructural Protein NS1 Are Modulated In Vitro by the Phosphorylation State of the Polypeptide
1998 · Jürg P. F. Nüesch, Romuald Corbau, et al. · Journal of Virology · 49
Regulation of MVM NS1 by Protein Kinase C: Impact of Mutagenesis at Consensus Phosphorylation Sites on Replicative Functions and Cytopathic Effects
2000 · Romuald Corbau, Valérie Duverger, et al. · Virology · 47
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Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease
2023 · Jey M. Jeyakumar, Azadeh Kia, et al. · Gene Therapy · 43
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Replicative Functions of Minute Virus of Mice NS1 Protein Are Regulated In Vitro by Phosphorylation through Protein Kinase C
1998 · Jürg P. F. Nüesch, Sabine Dettwiler, et al. · Journal of Virology · 39
Regulation of Minute Virus of Mice NS1 Replicative Functions by Atypical PKCλ In Vivo
2002 · Jürg P. F. Nüesch, Sylvie Lachmann, et al. · Journal of Virology · 38
Pyrazole NNRTIs 1: Design and initial optimisation of a novel template
2009 · Charles E. Mowbray, Catherine Burt, et al. · Bioorganic & Medicinal Chemistry Letters · 37
Phosphorylation of the Viral Nonstructural Protein NS1 during MVMp Infection of A9 Cells
1999 · Romuald Corbau, Nathalie Salomé, et al. · Virology · 36
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Pyrazole NNRTIs 3: Optimisation of physicochemical properties
2009 · Charles E. Mowbray, Romuald Corbau, et al. · Bioorganic & Medicinal Chemistry Letters · 31
HCV-NS3 inhibitors: Determination of their kinetic parameters and mechanism
2009 · María Victoria Flores, Joanne Strawbridge, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 29
Comparison of the Non‐Nucleoside Reverse Transcriptase Inhibitor Lersivirine with its Pyrazole and Imidazole Isomers
2011 · Lyn H. Jones, Gill Allan, et al. · Chemical Biology & Drug Design · 25
Transactivation of a cellular promoter by the NS1 protein of the parvovirus minute virus of mice through a putative hormone-responsive element
1996 · J M Vanacker, R Corbau, et al. · Journal of Virology · 23
Differences in wild-type– and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies
2022 · Jonathan H. Foley, Erald Shehu, et al. · Blood Advances · 16
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First-in-human study of a liver-directed AAV gene therapy (FLT190) in Fabry disease
2020 · Derralynn A. Hughes, Niten Patel, et al. · Molecular Genetics and Metabolism · 12
Optimization of 5‐Aryloxyimidazole Non‐Nucleoside Reverse Transcriptase Inhibitors
2008 · Lyn H. Jones, Gill Allan, et al. · ChemMedChem · 12
FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1
2025 · Fabrizio Comper, Carlos J. Miranda, et al. · Molecular Therapy · 10
Liver-directed gene therapy corrects Fabry disease in mice
2019 · Jey Jeyakumar, Azadeh Kia, et al. · Molecular Genetics and Metabolism · 9
Identification of novel FLT3 kinase inhibitors
2013 · Daphnie Pauwels, Hugo Klaassen, et al. · European Journal of Medicinal Chemistry · 7
HIV-1 reverse transcriptase structure-based drug design: crystals to clinic
2007 · C. Phillips, S. Irving, et al. · Acta Crystallographica Section A Foundations of Crystallography · 7
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Efficacy Evaluation of Liver-Directed Gene Therapy in Fabry Mice
2018 · Azadeh Kia, Jenny McIntosh, et al. · Blood · 6
Liver-Directed AAV Gene Therapy for Gaucher Disease
2019 · Carlos J Miranda, Miriam Canavese, et al. · Blood · 5
Works count: 41
Citation count: 988
H-index: 16
I10-index: 20
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