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Barbara G. Utterback

Observed names: B G Utterback, Barbara G Utterback, Barbara Utterback
OpenAlex ID: A5111656522
Drotrecogin Alfa (Activated) for Adults with Severe Sepsis and a Low Risk of Death
2005 · Edward Abraham, Pierre-François Laterre, et al. · New England Journal of Medicine · 875
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Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]
2004 · Gary T Kinasewitz, S Betty Yan, et al. · Critical Care · 361
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Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications
2000 · Rolf M. Mesters, Jeff Helterbrand, et al. · Critical Care Medicine · 197
Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial
2003 · Jean-François Dhainaut, Pierre-François Laterre, et al. · Intensive Care Medicine · 154
Differential Activation of Cytosolic Phospholipase A2 (cPLA2) by Thrombin and Thrombin Receptor Agonist Peptide in Human Platelets. EVIDENCE FOR ACTIVATION OF cPLA2 INDEPENDENT OF THE MITOGEN-ACTIVATED PROTEIN KINASES ERK1/2
1995 · Ruth M. Kramer, Edda F. Roberts, et al. · Journal of Biological Chemistry · 127
Safety, Pharmacokinetics, and Pharmacodynamics of Drotrecogin Alfa (Activated) in Children With Severe Sepsis
2004 · Phil Barton, Andre C. Kalil, et al. · PEDIATRICS · 123
The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (PROWESS): Role, methodology, and results*
2003 · Jean-François Dhainaut, Pierre-François Laterre, et al. · Critical Care Medicine · 94
ENHANCE: Results of a global open-label trial of drotrecogin alfa (activated) in children with severe sepsis*
2006 · Brahm Goldstein, Simon Nadel, et al. · Pediatric Critical Care Medicine · 61
Dibasic Benzo[b]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relationships, and Binding Orientation
1997 · Daniel J. Sall, Jolie A. Bastian, et al. · Journal of Medicinal Chemistry · 54
Non-Peptide RGD Surrogates Which Mimic a Gly-Asp β-Turn: Potent Antagonists of Platelet Glycoprotein IIb−IIIa
1997 · Matthew J. Fisher, Bruce Gunn, et al. · Journal of Medicinal Chemistry · 50
Decreased protein C, protein S, and antithrombin levels are predictive of poor outcome in Gram-negative sepsis caused by Burkholderia pseudomallei
2005 · Steven P. LaRosa, Steven M. Opal, et al. · International Journal of Infectious Diseases · 45
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Safety and tolerability of duloxetine in the acute management of diabetic peripheral neuropathic pain: analysis of pooled data from three placebo-controlled clinical trials
2010 · Jerry A Hall, Fujun Wang, et al. · Expert Opinion on Drug Safety · 30
Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists
1997 · Daniel J. Sall, Ann E. Arfsten, et al. · Journal of Medicinal Chemistry · 22
International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety
2007 · Pierre-Francois Laterre, David R. Nelson, et al. · Journal of Critical Care · 20
Synthesis of a tritium-labeled indolidan analog and its use as a radioligand for phosphodiesterase-inhibitor cardiotonic binding sites
1989 · David W. Robertson, Joseph H. Krushinski, et al. · Journal of Medicinal Chemistry · 18
Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2: sidechain optimization and demonstration of in vivo efficacy
1999 · Minsheng Zhang, Dianna L. Bailey, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Dihydroisoquinolone RGD mimics. Exploration of the aspartate isostere
1997 · Matthew J. Fisher, Bruce P. Gunn, et al. · Bioorganic & Medicinal Chemistry Letters · 11
Fused bicyclic Gly-Asp β-turn mimics with potent affinity for GPIIb-IIIa. Exploration of the arginine isostere
2000 · Matthew J. Fisher, Ulrich Giese, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Development of Dual-Acting Agents for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition. 3. Synthesis and Biological Activities of Oxazolecarboxamide-Substituted ω-Phenyl-ω-(3-pyridyl)alkenoic Acid Derivatives and Related Compounds
1998 · Kumiko Takeuchi, Todd J. Kohn, et al. · Journal of Medicinal Chemistry · 10
Fused Bicyclic Gly-Asp β-Turn Mimics with Specific Affinity for GPIIb-IIIa
1999 · Matthew J. Fisher, Ann E. Arfstan, et al. · Journal of Medicinal Chemistry · 8
Cardiac inotropic responses to calcium and forskolin are not altered by prolonged isoproterenol infusion
1990 · Nancy Bowling, Virginia L. Wyss, et al. · European Journal of Pharmacology · 8
LY249933
1989 · Donald R. Holland, James H. Wikel, et al. · Journal of Cardiovascular Pharmacology · 8
Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition-I. Synthesis, structure-activity relationship, and evaluation of substituted (ω-phenyl-ω)-(3-pyridyl)alkenoic acids
1994 · Kumiko Takeuchi, Anne M. Happ, et al. · Bioorganic & Medicinal Chemistry · 6
Biochemical and pharmacological activity of arene-fused prostacyclin analogues on human platelets
1994 · Joseph A. Jakubowski, Barbara G. Utterback, et al. · Prostaglandins · 5
Platelet glycoprotein IIb–IIIa receptor (GPIIb–IIIa) antagonists derived from amidinoindoles
1996 · Daniel J. Sall, Ann E. Arfsten, et al. · Bioorganic & Medicinal Chemistry Letters · 4
Works count: 27
Citation count: 2,322
H-index: 15
I10-index: 19
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