Author

Toshiharu Ohta

Observed names: Ohta, Toshiharu, T. OHTA, TOSHIHARU OHTA, Toshiharu OHTA, Toshiharu. Ohta

Observed institutions: Kanazawa University, Daiichi-Sankyo (Japan), University of Rochester, The University of Tokyo

OpenAlex ID: A5111674077

Inhibitors of Efflux Pumps in Pseudomonas a eruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

1999 · Thomas E. Renau, Roger Léger, et al. · Journal of Medicinal Chemistry · 261

Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

2003 · Thomas E Renau, Roger Léger, et al. · Bioorganic & Medicinal Chemistry Letters · 98

Synthesis and Antifungal Activity of Rhodopeptin Analogues. 2. Modification of the West Amino Acid Moiety

2000 · Kiyoshi Nakayama, Haruko C. Kawato, et al. · Organic Letters · 87

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

2003 · Kiyoshi Nakayama, Yohei Ishida, et al. · Bioorganic & Medicinal Chemistry Letters · 84

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model

2003 · Kiyoshi Nakayama, Haruko Kawato, et al. · Bioorganic & Medicinal Chemistry Letters · 66

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds

2003 · Kiyoshi Nakayama, Yohei Ishida, et al. · Bioorganic & Medicinal Chemistry Letters · 59

Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

2001 · Thomas E Renau, Roger Léger, et al. · Bioorganic & Medicinal Chemistry Letters · 59

Acid-catalyzed reactions of N-arylhydroxylamines and related compounds with benzene. Iminium-benzenium ions

1981 · Koichi Shudo, Toshiharu Ohta, et al. · Journal of the American Chemical Society · 54

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety

2004 · Kiyoshi Nakayama, Noriko Kuru, et al. · Bioorganic & Medicinal Chemistry Letters · 51

Synthesis of the spirocyclic center of fredericamycin a by phenoxy-enoxy radical coupling

1985 · Andrew S. Kende, Frank H. Ebetino, et al. · Tetrahedron Letters · 39

Design, synthesis, and biological activity of piperidine diamine derivatives as factor Xa inhibitor

2007 · Akiyoshi Mochizuki, Yumi Nakamoto, et al. · Bioorganic & Medicinal Chemistry Letters · 38

The chemistry of indoles. XXXIX. A facile synthetic method for 7-substituted indoles.

1987 · MASANORI SOMEI, YOSHIHIRO SAIDA, et al. · Chemical and Pharmaceutical Bulletin · 38

PDF

Protonation of nitro groups. Diprotonation of .beta.-nitrostyrenes in trifluoromethanesulfonic acid

1986 · Tomohiko. Ohwada, Toshiharu. Ohta, et al. · Journal of the American Chemical Society · 37

Novel Peptidomimetics of the Antifungal Cyclic Peptide Rhodopeptin: Design of Mimetics Utilizing Scaffolding Methodology

2001 · Kiyoshi Nakayama, Haruko C. Kawato, et al. · Organic Letters · 34

Syntheses of Wasabi Phytoalexin (Methyl 1-Methoxyindole-3-carboxylate) and Its 5-Iodo Derivative, and Their Nucleophilic Substitution Reactions

2001 · Masanori Somei, Asuka Tanimoto, et al. · Heterocycles · 34

Nitroethylene yields (N,N-dihydroxyiminium)methylium dication in trifluoromethanesulfonic acid. Dications stabilized by Y delocalization

1987 · Tomohiko Ohwada, Akiko Itai, et al. · Journal of the American Chemical Society · 34

Novel electrophilic species equivalent to .alpha.-keto cations. Reactions of 0,0-diprotonated nitro olefins with benzenes yield arylmethyl ketones

1989 · Kazuaki Okabe, Tomohiko Ohwada, et al. · The Journal of Organic Chemistry · 33

Synthesis of a mutagenic principle isolated from tryptophan pyrolysate.

1977 · KEI TAKEDA, TOSHIHARU OHTA, et al. · Chemical and Pharmaceutical Bulletin · 32

PDF

Acid-catalyzed reaction of arylhydroxylamines with benzene. Selectivity of the reaction sites

1975 · Toshihiko Okamoto, Koichi Shudo, et al. · Journal of the American Chemical Society · 32

Reductive phenylation of nitroarenes

1980 · Toshiharu Ohta, Ryosuke Machida, et al. · Journal of the American Chemical Society · 31

Novel Peptidomimetics of the Antifungal Cyclic Peptide Rhodopeptin: Synthesis of Mimetics and Their Antifungal Activity

2001 · Haruko C. Kawato, Kiyoshi Nakayama, et al. · Organic Letters · 29

Mutagenicities of phenacetin and its metabolites

1978 · Koichi Shudo, Toshiharu Ohta, et al. · Mutation Research/Genetic Toxicology · 29

Reactions of O,O-diprotonated nitro olefins with benzenes. Formations of phenylacetones, 4H-1,2-benzoxazines and biarylacetone oximes

1990 · Tomohiko Ohwada, Kazuaki Okabe, et al. · Tetrahedron · 28

Reaction of β-nitrostyrenes with benzene catalyzed by trifluoromethanesulfonic acid. Formation and reaction of n,n-dihydroxyiminium-benzyl dications

1987 · Tomohiko Ohwada, Toshiharu Ohta, et al. · Tetrahedron · 26

Synthesis of (±)-Clavicipitic Acid and Its Derivatives

1994 · Masanori Somei, Shoichi Hamamoto, et al. · Heterocycles · 20

Works count: 98

Citation count: 1,646

H-index: 24

I10-index: 43