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Ryoko Yoshikawa

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity
2003 · Shigeyuki Chaki, Ryoko Yoshikawa, et al. · Neuropharmacology · 262
Design, synthesis and structure–affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands
2003 · Taketoshi Okubo, Ryoko Yoshikawa, et al. · Bioorganic & Medicinal Chemistry · 160
Synthesis, SARs, and Pharmacological Characterization of 2-Amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent, Selective, and Orally Active Group II Metabotropic Glutamate Receptor Agonists
2000 · Atsuro Nakazato, Toshihito Kumagai, et al. · Journal of Medicinal Chemistry · 116
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106
1999 · Shigeru Okuyama, Shigeyuki Chaki, et al. · Life Sciences · 92
Binding characteristics of DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors
1999 · Shigeyuki Chaki, Takeo Funakoshi, et al. · European Journal of Pharmacology · 85
Synthesis, in Vitro Pharmacology, Structure−Activity Relationships, and Pharmacokinetics of 3-Alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent and Selective Group II Metabotropic Glutamate Receptor Antagonists
2004 · Atsuro Nakazato, Kazunari Sakagami, et al. · Journal of Medicinal Chemistry · 60
Design, synthesis, and structure?activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands*1
2004 · Taketoshi Okubo, Ryoko Yoshikawa, et al. · Bioorganic & Medicinal Chemistry · 59
Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (MGS0039): A potent and orally active group II mGluR antagonist with antidepressant-like potential
2006 · Akito Yasuhara, Masato Nakamura, et al. · Bioorganic & Medicinal Chemistry · 43
A selective dopamine D4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile
1999 · Shigeru Okuyama, Naoya Kawashima, et al. · Life Sciences · 28
In Vitro and In Vivo Characterization of the Dopamine D4 Receptor, Serotonin 5-HT2AReceptor and Alpha-1 Adrenoceptor Antagonist (R)-(+)-2-Amino-4-(4-Fluorophenyl)- 5-[1-[4-(4-Fluorophenyl)-4-Oxobutyl]Pyrrolidin-3-yl]Thiazole (NRA0045)
1997 · Shigeru Okuyama, Shigeyuki Chaki, et al. · Journal of Pharmacology and Experimental Therapeutics · 27
Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens
2006 · Shigeyuki Chaki, Ryoko Yoshikawa, et al. · Neuroscience Letters · 23
Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist
2008 · Kazunari Sakagami, Akito Yasuhara, et al. · Bioorganic & Medicinal Chemistry · 21
In vitro and in vivo pharmacological profile of 5-{2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl}-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic
2002 · Takeo Funakoshi, Shigeyuki Chaki, et al. · Life Sciences · 20
Synthesis, in vitro pharmacology, and structure–activity relationships of 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as mGluR2 antagonists
2006 · Akito Yasuhara, Kazunari Sakagami, et al. · Bioorganic & Medicinal Chemistry · 16
In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats
1999 · Shigeyuki Chaki, Takeo Funakoshi, et al. · Neuropharmacology · 12
Neuroprotective effect of 4′-(4-methylphenyl)-2,2′:6′,2-terpyridine trihydrochloride, a novel inducer of nerve growth factor
1996 · Kyoko Yamamoto, Ryoko Yoshikawa, et al. · Life Sciences · 3
In vivo receptor occupancy of an atypical antipsychotic, NRA0045, in rats
1998 · Shigeyuki Chaki, Takeo Funakoshi, et al. · The Japanese Journal of Pharmacology · 1
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106
1999 · Ryoko Yoshikawa, Shigeyuki Chaki, et al. · The Japanese Journal of Pharmacology
In vitro pharmacological profile of atypical antipsychotics, NRA0160 and NRA0215
1998 · Takeo Funakoshi, Shigeyuki Chaki, et al. · The Japanese Journal of Pharmacology
In vitro characterization of dopamine D4 receptor antagonist, (R)-(+)-2-amino-4-(4-fluorophenyl)-5-[1-[4-(4 - fluorophenyl) - 4 - oxobutyl] Pyrrolidin - 3 - yl] thiazole (NRA0045)
1997 · Ryoko Yoshikawa, Shigeyuki Chaki, et al. · The Japanese Journal of Pharmacology
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Works count: 20
Citation count: 1,028
H-index: 14
I10-index: 15
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