Author

Alan G. Roach

Observed names: A G Roach, A Roach, A. G. ROACH, A. G. Roach, A. Roach, A.G. ROACH, A.G. Roach, AG Roach, ALAN G. ROACH, Alan G Roach, Alan Roach, Roach, A, Roach, Alan G.

Observed institutions: Aston University, Pfizer (United Kingdom), Harefield Hospital, Summit (United Kingdom), Gloucestershire Royal Hospital, Addenbrooke's Hospital, Reckitt Benckiser Health Limited (United Kingdom), Imperial College London, University of Bath, Cardiff University, University of Wales

OpenAlex ID: A5111700973

Studies on RX 781094: a selective, potent and specific antagonist of α2‐adrenoceptors

1983 · J.C. Doxey, A.G. Roach, et al. · British Journal of Pharmacology · 356

Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery

2008 · T P Barros, W K Alderton, et al. · British Journal of Pharmacology · 281

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Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants

2007 · Stephane Berghmans, Julia Hunt, et al. · Epilepsy Research · 277

Non-Associative Learning in Larval Zebrafish

2007 · Jonathan D Best, Stéphane Berghmans, et al. · Neuropsychopharmacology · 244

Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery

2008 · Stéphane Berghmans, Paul Butler, et al. · Journal of Pharmacological and Toxicological Methods · 188

Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish

2008 · Oleg Anichtchik, Heike Diekmann, et al. · Journal of Neuroscience · 184

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Comparison of the ?-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine

1984 · J. C. Doxey, A. C. Lane, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 167

The pharmacology of prazosin, a novel antihypertensive agent

1980 · Icilio Cavero, Alan G. Roach · Life Sciences · 154

Human Vascular Smooth Muscle Cells Express Receptors for CC Chemokines

1998 · Ian M. Hayes, Nicola J. Jordan, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 139

CENTRAL α‐ AND β‐ADRENOCEPTORS MODIFYING ARTERIAL BLOOD PRESSURE AND HEART RATE IN CONSCIOUS CATS

1974 · M.D. DAY, A.G. ROACH · British Journal of Pharmacology · 113

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Decreased BDNF Levels Are a Major Contributor to the Embryonic Phenotype of Huntingtin Knockdown Zebrafish

2009 · Heike Diekmann, Oleg Anichtchik, et al. · Journal of Neuroscience · 95

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Chemokine production by human vascular smooth muscle cells: modulation by IL‐13

1997 · Nicola J. Jordan, Malcolm L. Watson, et al. · British Journal of Pharmacology · 90

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Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

2010 · Clare E. Buckley, Anita Marguerie, et al. · Neuropharmacology · 86

.alpha.-Adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic .alpha.2-adrenoreceptor antagonists and potential antidepressants

1983 · Christopher B. Chapleo, Peter L. Myers, et al. · Journal of Medicinal Chemistry · 85

A Virtual Screening Approach to Finding Novel and Potent Antagonists at the Melanin-Concentrating Hormone 1 Receptor

2004 · David E. Clark, Christopher Higgs, et al. · Journal of Medicinal Chemistry · 79

.alpha.-Adrenoceptor reagents. 2. Effects of modification of the 1,4-benzodioxan ring system on .alpha.-adrenoreceptor activity

1984 · Christopher B. Chapleo, Peter L. Myers, et al. · Journal of Medicinal Chemistry · 74

α2‐Adrenoceptor agonists induce mydriasis in the rat by an action within the central nervous system

1983 · T.L. Berridge, B. Gadie, et al. · British Journal of Pharmacology · 72

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The mechanism of the antihypertensive action of α-methyldopa in hypertensive rats

1973 · M.D. Day, A.G. Roach, et al. · European Journal of Pharmacology · 71

Tissue levels of several radiolabelled beta-adrenoceptor antagonists after intravenous administration in rats.

1979 · J A Street, B A Hemsworth, et al. · PubMed · 60

β-Adrenergic Receptors in the Central Nervous System of the Cat concerned with Control of Arterial Blood Pressure and Heart Rate

1973 · M. D. DAY, A. G. ROACH · Nature New Biology · 60

Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits

1978 · Icilio Cavero, Simone Fenard, et al. · European Journal of Pharmacology · 58

Effects of Prazosin and Phentolamine on Cardiac Presynaptic α-Adrenoceptors in the Cat, Dog and Rat

1978 · A. G. Roach, F. Lefèvre, et al. · Clinical and Experimental Hypertension · 56

PRESYNAPTIC α‐ADRENORECEPTORS; IN VITRO METHODS AND PREPARATIONS UTILISED IN THE EVALUATION OF AGONISTS AND ANTAGONISTS

1980 · J. C. DOXEY, A. G. ROACH · Journal of Autonomic Pharmacology · 53

Effects of Clonidine, Prazosin and Phentolamine on Heart Rate and Coronary Sinus Catecholamine Concentration During Cardioaccelerator Nerve Stimulation in Spinal Dogs

1979 · I. CAVERO, T. DENNIS, et al. · British Journal of Pharmacology · 50

Cardiovascular Effects of ?-adrenoreceptor Blocking Agents After Intracerebroventricular Administration in Conscious Normotensive Cats

1974 · M. D. Day, A. G. Roach · Clinical and Experimental Pharmacology and Physiology · 50

Works count: 98

Citation count: 4,311

H-index: 35

I10-index: 65