Get started
Author

Tianan Fang

Observed name: Fang, Tianan
ORCID: 0009-0002-1539-2943
Observed ORCID: 0009-0002-1539-2943
OpenAlex ID: A5111702897
Improved Synthesis of Enantiopure Sulfinimines (Thiooxime S -Oxides) from p -Toluenesulfinamide and Aldehydes and Ketones
1999 · Franklin A. Davis, Yulian Zhang, et al. · The Journal of Organic Chemistry · 194
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
2021 · Andrew K. Dilger, Kumar B. Pabbisetty, et al. · Journal of Medicinal Chemistry · 116
Aza-Darzens Asymmetric Synthesis of N-(p-Toluenesulfinyl)aziridine 2-Carboxylate Esters from Sulfinimines (N-Sulfinyl Imines)
1999 · Franklin A. Davis, Hu Liu, et al. · The Journal of Organic Chemistry · 102
δ-Amino β-Keto Esters, a Designed Polyfunctionalized Chiral Building Block for Alkaloid Synthesis. Asymmetric Synthesis of (R)-(+)-2-Phenylpiperidine and (−)-SS20846A
2000 · Franklin A. Davis, Bin Chao, et al. · Organic Letters · 66
Asymmetric Synthesis of 2H-Azirine 2-Carboxylate Esters
1999 · Franklin A. Davis, Hu Liu, et al. · The Journal of Organic Chemistry · 65
Asymmetric Synthesis of Substituted Prolines from δ-Amino β-Ketoesters. Methyl (2S,5R)-(+)-5-Phenylpyrrolidine-2-carboxylate
2002 · Franklin A. Davis, Tianan Fang, et al. · Organic Letters · 62
Asymmetric Synthesis of the Four Stereoisomers of 4-Hydroxypipecolic Acid
2000 · Franklin A. Davis, Tianan Fang, et al. · Synthesis · 47
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties
2015 · Donald J.P. Pinto, Joanne M. Smallheer, et al. · Bioorganic & Medicinal Chemistry Letters · 45
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
2017 · James R. Corte, Tianan Fang, et al. · Journal of Medicinal Chemistry · 42
PDF
Phenylimidazoles as Potent and Selective Inhibitors of Coagulation Factor XIa with in Vivo Antithrombotic Activity
2014 · Jon J. Hangeland, Todd J. Friends, et al. · Journal of Medicinal Chemistry · 42
Structure–activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties
2008 · James R. Corte, Tianan Fang, et al. · Bioorganic & Medicinal Chemistry Letters · 33
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups
2019 · James R. Corte, Donald J. P. Pinto, et al. · Journal of Medicinal Chemistry · 30
Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species
2020 · Wu Yang, Yufeng Wang, et al. · Journal of Medicinal Chemistry · 27
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
2016 · James R. Corte, Tianan Fang, et al. · Bioorganic & Medicinal Chemistry · 24
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
2017 · James R. Corte, Wu Yang, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Asymmetric synthesis of alkaloids using polyfunctionalized chiral building blocks
2002 · Franklin A. Davis, Bin Chao, et al. · Heteroatom Chemistry · 22
Pyridine and pyridinone-based factor XIa inhibitors
2014 · James R. Corte, Tianan Fang, et al. · Bioorganic & Medicinal Chemistry Letters · 21
Characterization of a new class of selective nonsteroidal progesterone receptor agonists
2004 · Yu Dong, Jacques Y Roberge, et al. · Steroids · 18
Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability
2019 · Charles G. Clark, Karen A. Rossi, et al. · Bioorganic & Medicinal Chemistry Letters · 15
Asymmetric Synthesis Using Sulfinimines (N-Sulfinyl Imines)
2005 · Franklin A. Davis, Bin Yang, et al. · Phosphorus, sulfur, and silicon and the related elements · 11
Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa
2020 · Tianan Fang, James R. Corte, et al. · Bioorganic & Medicinal Chemistry Letters · 8
ChemInform Abstract: δ‐Amino β‐Keto Esters, a Designed Polyfunctionalized Chiral Building Block for Alkaloid Synthesis. Asymmetric Synthesis of (R)‐(+)‐2‐Phenylpiperidine and (‐)‐SS20846A.
2000 · Franklin A. Davis, Bin Chao, et al. · ChemInform · 1
ChemInform Abstract: Improved Synthesis of Enantiopure Sulfinimines (Thiooxime S‐Oxides) from p‐Toluenesulfinamide and Aldehydes and Ketones.
1999 · Franklin A. Davis, Yulian Zhang, et al. · ChemInform · 1
CCDC 2074385: Experimental Crystal Structure Determination
2021 · Dilger, Andrew K., Pabbisetty, Kumar B., et al. · The Cambridge Structural Database
Asymmetric Synthesis of Alkaloids Using Polyfunctionalized Chiral Building Blocks.
2002 · Franklin A. Davis, Bin Chao, et al. · ChemInform
Works count: 27
Citation count: 1,015
H-index: 18
I10-index: 20
Year
Topic
Type