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Lynn Bedford

Observed name: Bedford, Lynn
OpenAlex ID: A5111710332
Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
2010 · Lynn Bedford, James Lowe, et al. · Nature Reviews Drug Discovery · 563
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Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
2008 · Lynn Bedford, David Hay, et al. · Journal of Neuroscience · 327
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Assembly, structure, and function of the 26S proteasome
2010 · Lynn Bedford, Simon Paine, et al. · Trends in Cell Biology · 252
The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction
2020 · Bo Pan, Jie Li, et al. · Circulation Research · 125
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Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway
2014 · Shun Kageyama, Yu-shin Sou, et al. · Journal of Biological Chemistry · 117
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Id4 is required for the correct timing of neural differentiation
2005 · Lynn Bedford, Robert Walker, et al. · Developmental Biology · 90
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The ubiquitin–proteasome system and neurodegenerative disorders
2005 · Robert Layfield, James Lowe, et al. · Essays in Biochemistry · 72
CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases
2011 · Ritchie Williamson, Lidy van Aalten, et al. · Journal of Alzheimer s Disease · 64
Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway
2017 · Aslihan Ugun-Klusek, Michael H Tatham, et al. · Cell Death and Disease · 60
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Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation
2018 · Aslihan Ugun-Klusek, Theodosis S. Theodosi, et al. · Redox Biology · 56
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Alcohol-Related Brain Damage in Humans
2014 · Amaia M. Erdozain, Benito Morentin, et al. · PLoS ONE · 51
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Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration
2009 · Simon Paine, Lynn Bedford, et al. · Neuroscience Letters · 41
The UPS and autophagy in chronic neurodegenerative disease: Six of one and half a dozen of the other—Or not?
2009 · Lynn Bedford, Simon Paine, et al. · Autophagy · 28
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Is malfunction of the ubiquitin proteasome system the primary cause of α-synucleinopathies and other chronic human neurodegenerative disease?
2008 · Lynn Bedford, David Hay, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 28
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Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein
2013 · Simon M. L. Paine, Glenn Anderson, et al. · PLoS ONE · 27
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Diverse polyubiquitin chains accumulate following 26S proteasomal dysfunction in mammalian neurones
2011 · Lynn Bedford, Robert Layfield, et al. · Neuroscience Letters · 27
Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones
2013 · Jamal Elkharaz, Aslihan Ugun-Klusek, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 26
Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons
2018 · Philippine C. Geiszler, Aslihan Ugun-Klusek, et al. · Scientific Reports · 13
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Does video feedback & peer observation offer a valid method of reinforcing oral presentation training for undergraduate biochemists?
2019 · Timothy Simpson, Kathryn Holden, et al. · Higher Education Pedagogies · 12
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Heterozygosity for the proteasomal Psmc1 ATPase is insufficient to cause neuropathology in mouse brain, but causes cell cycle defects in mouse embryonic fibroblasts
2012 · Nooshin Rezvani, Jamal Elkharaz, et al. · Neuroscience Letters · 8
Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation
2019 · Aslihan Ugun-Klusek, Theodosis S. Theodosi, et al. · Newcastle University ePrints (Newcastle Univesity)
The wakefulness promoting agent modafinil ameliorates experimental autoimmune encephalomyelitis
2014 · Lynn Bedford, James Crooks, et al. · Journal of Neuroimmunology
Protein Degradation in Neurodegeneration: The Ubiquitin Pathway
2011 · Lynn Bedford, Robert Layfield, et al.
Can neurodegeneration be separated from neuropathological hallmarks of chronic idiopathic human neurodegenerative disease? A perspective from modelling!
2011 · Simon Paine, James Lowe, et al. · Biochemical Society Transactions
Parkinson's Disease Society 6th Spring Conference for Researchers
2009 · Lynn Bedford · Progress in Neurology and Psychiatry
Works count: 27
Citation count: 1,987
H-index: 17
I10-index: 19
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