Author

Claude Hélène

Observed names: C HELENE, C Helene, C Hèlène, C Hélène, C Héléne, C. HELENE, C. Helene, C. HÉLÈNE, C. HÉLÉNE, C. Hélène, C. Héléne, CLAUDE HELENE, CLAUDE HÉLÈNE, CLAUDE HÉLÉNE, Claude HELENE, Claude Helene, Claude Helénè, Claude HÉLÈNE, Claude Hèlène, Claude Hèléne, Claude Héléne, Claude. Helene, HELENE, C, Helene, Claude, Hélène Claude, Hélène, C., Hélène, Claude

Observed institutions: University of Geneva, Université d'Orléans, Hôpital Necker-Enfants Malades, Oak Ridge National Laboratory, Centre National de la Recherche Scientifique, École Polytechnique, University of Liverpool, Inserm, Institut Pasteur, Collège de France, University of Cambridge, Institut Gustave Roussy, ETH Zurich, Institut de Biologie et de Chimie des Protéines, Institut de Biologie Physico-Chimique, Centre de Biophysique Moléculaire, Muséum national d'Histoire naturelle, Centre Oscar Lambret, Institut de Chimie de Clermont-Ferrand, Laboratoire de Synthèse Organique, ADERSE, Musée national d'histoire naturelle Luxembourg, Structure et Instabilité des Génomes, Université Paris Descartes, Laboratory of Organic Chemistry, Université Blaise Pascal, Conception, synthèse et vectorisation de biomolécules, Universitat de les Illes Balears, Institut Curie

OpenAlex ID: A5111714765

Specific regulation of gene expression by antisense, sense and antigene nucleic acids

1990 · Claude Hélène, Jean-Jacques Toulmé · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 768

Sequence‐Specific Recognition and Modification of Double‐Helical DNA by Oligonucleotides

1993 · Nguyen T. Thuong, Claude Hélène · Angewandte Chemie International Edition in English · 624

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands

2002 · J. F. Riou, L. Guittat, et al. · Proceedings of the National Academy of Sciences · 394

G-quadruplex DNA: A target for drug design

1998 · Jean-Louis Mergny, Claude Hélène · Nature Medicine · 384

Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into ani-motif

1994 · Jean-Louis Leroy, Maurice Guéron, et al. · Nucleic Acids Research · 300

Intramolecular Folding of Pyrimidine Oligodeoxynucleotides into an i-DNA Motif

1995 · Jean-Louis Mergny, Laurent Lacroix, et al. · Journal of the American Chemical Society · 297

Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay

2001 · Jean-Louis Mergny, Laurent Lacroix, et al. · Proceedings of the National Academy of Sciences · 291

Triple Helix-Specific Ligands

1992 · J. L. Mergny, G. Duval-Valentin, et al. · Science · 283

Triple helix formation and the antigene strategy for sequence-specific control of gene expression

1999 · D. Praseuth, A.L. Guieysse, et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 262

Specific inhibition of transcription by triple helix-forming oligonucleotides.

1992 · G Duval-Valentin, N T Thuong, et al. · Proceedings of the National Academy of Sciences · 241

Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides

1989 · C. Cazenave, C.A. Stein, et al. · Nucleic Acids Research · 238

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Fullerene–Oligonucleotide Conjugates: Photoinduced Sequence‐Specific DNA Cleavage

1995 · Alexandre S. Boutorine, Masashi Takasugi, et al. · Angewandte Chemie International Edition in English · 235

Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.

1991 · M Takasugi, A Guendouz, et al. · Proceedings of the National Academy of Sciences · 226

Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatched

1992 · M. Rougee, B. Faucon, et al. · Biochemistry · 224

Interactions between functional groups in protein-nucleic acid associations

1982 · Claude Hélène, Gérald Lancelot · Progress in Biophysics and Molecular Biology · 222

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Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides

1975 · Francine Brun, Jean J. Toulme, et al. · Biochemistry · 219

Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation.

1988 · D Praseuth, L Perrouault, et al. · Proceedings of the National Academy of Sciences · 214

The anti-gene strategy: control of gene expression by triplex-forming-oligonucleotides.

1991 · C Hélène · PubMed · 208

Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides

1990 · L. Perrouault, U. Asseline, et al. · Nature · 200

Short modified antisense oligonucleotides directed against Ha‐ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation.

1991 · T. Saison‐Behmoaras, B. Tocqué, et al. · The EMBO Journal · 199

Interactions of Oligopeptides With Nucleic Acid

1981 · Claude Helene, Jean-Claude Maurizot, et al. · Critical Reviews in Biochemistry and Molecular Biology · 181

Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.

1989 · J S Sun, J C François, et al. · Proceedings of the National Academy of Sciences · 179

Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides.

1984 · U Asseline, M Delarue, et al. · Proceedings of the National Academy of Sciences · 171

Sequence specificity in triple helix formation: experimental and theoretical studies of the effect of mismatches on triplex stability

1991 · Jean Louis Mergny, Jian Sheng Sun, et al. · Biochemistry · 170

Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice.

1994 · G Schwab, C Chavany, et al. · Proceedings of the National Academy of Sciences · 167

Works count: 446

Citation count: 20,740

H-index: 78

I10-index: 289