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Yunxin Y. Bo
Observed names:
Yun-xin Bo,
Yunxin Bo,
Yun‐Xin Bo
Institution:
Amgen (United States)
Observed institutions:
Amgen (United States),
Harvard University,
University of Alberta,
Chinese Academy of Sciences,
Shanghai Institute of Materia Medica,
Technische Universität Braunschweig
show all 6
OpenAlex ID:
A5111737671
Enantioselective Total Synthesis of Aspidophytine
1999
·
Feng He
, Yunxin Bo
, et al.
·
Journal of the American Chemical Society
·
225
Highly Enantioselective Phase Transfer Catalyzed Alkylation of a 3-Oxygenated Propionic Ester Equivalent; Applications and Mechanism
1998
·
E. J. Corey
, Yunxin Bo
, et al.
·
Journal of the American Chemical Society
·
154
Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of N-Aryl Cinnamides
2004
·
Elizabeth M. Doherty
, Christopher Fotsch
, et al.
·
Journal of Medicinal Chemistry
·
104
Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate
2007
·
Elizabeth M. Doherty
, Christopher Fotsch
, et al.
·
Journal of Medicinal Chemistry
·
100
Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles
2006
·
Vassil I. Ognyanov
, Chenera Balan
, et al.
·
Journal of Medicinal Chemistry
·
86
Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure–Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives
2011
·
Nobuko Nishimura
, Aaron Siegmund
, et al.
·
Journal of Medicinal Chemistry
·
61
Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists
2012
·
Nuria A. Tamayo
, Yunxin Bo
, et al.
·
Journal of Medicinal Chemistry
·
56
Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases
2012
·
Adrian L. Smith
, Noel D. D’Angelo
, et al.
·
Journal of Medicinal Chemistry
·
51
Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511
2012
·
Mark H. Norman
, Kristin L. Andrews
, et al.
·
Journal of Medicinal Chemistry
·
49
Optimization of Potency and Pharmacokinetic Properties of Tetrahydroisoquinoline Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists
2014
·
Daniel B. Horne
, Nuria A. Tamayo
, et al.
·
Journal of Medicinal Chemistry
·
45
New, practical and effective sources of fluoride ion for desilylation to form carbon anions
1999
·
Jakob Busch-Petersen
, Yunxin Bo
, et al.
·
Tetrahedron Letters
·
45
Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues oftrans-Cinnamides
2007
·
Mark H. Norman
, Jiawang Zhu
, et al.
·
Journal of Medicinal Chemistry
·
44
Synthesis of (±)-Calicheamicinone by Two Related Methods
1996
·
D. L. J. Clive
, Yunxin Bo
, et al.
·
Journal of the American Chemical Society
·
35
Synthesis of Heterocycles by Tandem Reactions: Beckmann Rearrangements/Allylsilane Cyclizations
1991
·
Dieter Schinzer
, Yunxin Bo
·
Angewandte Chemie International Edition in English
·
34
Synthetic studies on calicheamicin γ1I—synthesis of(−)-calicheamicinone and models representing the four sugars and the aromatic system
2000
·
Derrick L. J. Clive
, Yong Tao
, et al.
·
Chemical Communications
·
31
Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis
2015
·
Nuria A. Tamayo
, Mark H. Norman
, et al.
·
Journal of Medicinal Chemistry
·
30
Synthesis and structure–activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold
2012
·
Ryan P. Wurz
, Longbin Liu
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
30
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists
2005
·
Ning Xi
, Yunxin Bo
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
27
Synthesis and X-ray crystal structure of (?)-calicheamicinone
1999
·
Derrick L.J. Clive
, Yunxin Bo
, et al.
·
Tetrahedron
·
25
Synthesis of (±)-Calicheamicinone by Two Methods
1998
·
Derrick L. J. Clive
, Yunxin Bo
, et al.
·
Journal of the American Chemical Society
·
24
The imidazo[1,2-a]pyridine ring system as a scaffold for potent dual phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitors
2015
·
Markian M. Stec
, Kristin L. Andrews
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
21
Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine) as a novel anti-arrhythmic agent
2012
·
Dong-lu Bai
, Wei-zhou Chen
, et al.
·
Acta Pharmacologica Sinica
·
21
PDF
Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides
2005
·
Christopher Fotsch
, Nianhe Han
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
19
Synthese von Heterocyclen durch Tandem‐reaktionen: Beckmann‐Umlagerungen/Allylsilan‐Cyclisierungen
1991
·
Dieter Schinzer
, Yunxin Bo
·
Angewandte Chemie
·
12
Substituted aryl pyrimidines as potent and soluble TRPV1 antagonists
2008
·
Markian M. Stec
, Yunxin Bo
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
11
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Works count:
33
Citation count:
1,355
H-index:
21
I10-index:
26
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