Author

Astrid A. Ortiz

Observed names: Astrid A Ortiz, Astrid Ortiz

Institution: Bristol-Myers Squibb (United States)

Observed institutions: Bristol-Myers Squibb (United States), New York State Psychiatric Institute, Columbia University

OpenAlex ID: A5111742491

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels

2001 · Valentin K. Gribkoff, John E. Starrett, et al. · Nature Medicine · 309

Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity

2007 · Joachim Rudolph, William P. Esler, et al. · Journal of Medicinal Chemistry · 160

A Novel Long-Acting Selective Neuropeptide Y2 Receptor Polyethylene Glycol-Conjugated Peptide Agonist Reduces Food Intake and Body Weight and Improves Glucose Metabolism in Rodents

2007 · Astrid A. Ortiz, Lucinda F. Milardo, et al. · Journal of Pharmacology and Experimental Therapeutics · 69

3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3 H )-one, BMS-191011: Opener of Large-Conductance Ca 2+ -Activated Potassium (Maxi-K) Channels, Identification, Solubility, and SAR

2007 · Jeffrey L. Romine, Scott W. Martin, et al. · Journal of Medicinal Chemistry · 60

Dihydropyridine Neuropeptide Y Y1 Receptor Antagonists

2002 · Graham S. Poindexter, Marc A. Bruce, et al. · Bioorganic & Medicinal Chemistry Letters · 55

Dual-acting peptide with prolonged glucagon-like peptide-1 receptor agonist and glucagon receptor antagonist activity for the treatment of type 2 diabetes

2007 · Thomas H Claus, Clark Q Pan, et al. · Journal of Endocrinology · 46

Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y1 receptor antagonist

2008 · Ildiko Antal-Zimanyi, Marc. A. Bruce, et al. · European Journal of Pharmacology · 40

Temporal changes in superoxide dismutase, glutathione peroxidase, and catalase levels in primary and peri-ischemic tissue

1993 · Sahebarao P. Mahadik, Tapas K. Makar, et al. · Molecular and Chemical Neuropathology · 40

Novel Selective Neuropeptide Y2 Receptor PEGylated Peptide Agonists Reduce Food Intake and Body Weight in Mice

2007 · Kevin J. Lumb, Lynn B. DeCarr, et al. · Journal of Medicinal Chemistry · 34

A long-acting selective neuropeptide Y2 receptor PEGylated peptide agonist reduces food intake in mice

2007 · Lynn B. DeCarr, Thomas M. Buckholz, et al. · Bioorganic & Medicinal Chemistry Letters · 28

Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives

2006 · Roger A. Smith, Zahra Fathi, et al. · Bioorganic & Medicinal Chemistry Letters · 26

Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists

2006 · Kevin W. Gillman, Mendi A. Higgins, et al. · Bioorganic & Medicinal Chemistry · 23

Synthesis of water-Soluble prodrugs of BMS-191011: A maxi-K channel opener targeted for post-stroke neuroprotection

2003 · Piyasena Hewawasam, Min Ding, et al. · Bioorganic & Medicinal Chemistry Letters · 20

Monosialoganglioside (GM1) restores membrane fatty acid levels in ischemic tissue after cortical focal ischemia in rat

1993 · Sahebarao P. Mahadik, Basalingappa L. Hungund, et al. · Neurochemistry International · 19

Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides

2004 · James R. Epperson, Marc A. Bruce, et al. · Bioorganic & Medicinal Chemistry · 16

Heterocyclic aminopyrrolidine derivatives as melatoninergic agents

2003 · Li-Qiang Sun, Jie Chen, et al. · Bioorganic & Medicinal Chemistry Letters · 15

Optimization of imidazole amide derivatives as cannabinoid-1 receptor antagonists for the treatment of obesity

2007 · Roger A. Smith, Zahra Fathi, et al. · Bioorganic & Medicinal Chemistry Letters · 14

Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists

2012 · Shuanghua Hu, Yazhong Huang, et al. · ACS Medicinal Chemistry Letters · 2

Nerve growth factor and the recovery of behavioral function after focal cortical infarction

1991 · Astrid Ortiz · Fordham Research Commons (Fordham University)

Works count: 19

Citation count: 976

H-index: 15

I10-index: 17