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Michael Rooney

Observed names: M. Rooney, M.T. Rooney, Michael T. Rooney, Michael T. V. Rooney, Michael T.V Rooney, Rooney, Michael
OpenAlex ID: A5111751540
Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)
2013 · Edward J. Hennessy, Ammar Adam, et al. · Journal of Medicinal Chemistry · 120
Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy
2015 · Aryun Kim, Amy Kutschke, et al. · Antimicrobial Agents and Chemotherapy · 81
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Hybridization Liquid Chromatography–Tandem Mass Spectrometry: An Alternative Bioanalytical Method for Antisense Oligonucleotide Quantitation in Plasma and Tissue Samples
2020 · Pei Li, Yuqing Gong, et al. · Analytical Chemistry · 69
Derivatized, swellable polymer microspheres for chemical transduction
1999 · W.Rudolf Seitz, Michael T.V Rooney, et al. · Analytica Chimica Acta · 39
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
2021 · Tamara Halkina, Jaclyn L. Henderson, et al. · Journal of Medicinal Chemistry · 36
An optically sensitive membrane for pH based on swellable polymer microspheres in a hydrogel
1999 · Michael T. V. Rooney, W. Rudolf Seitz · Analytical Communications · 34
SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3
2015 · Kerry E. Murphy-Benenato, Brian Dangel, et al. · ACS Medicinal Chemistry Letters · 30
Discovery of Efficacious Pseudomonas aeruginosa -Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model
2015 · Kerry E. Murphy-Benenato, Pratik R. Bhagunde, et al. · Journal of Medicinal Chemistry · 29
Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity
2015 · Edward J. Hennessy, Vibha Oza, et al. · Journal of Medicinal Chemistry · 25
Discovery of bacterial NAD+-dependent DNA ligase inhibitors: Improvements in clearance of adenosine series
2011 · Suzanne S. Stokes, Madhusudhan Gowravaram, et al. · Bioorganic & Medicinal Chemistry Letters · 23
A remotely interrogatable magnetochemical pH sensor
1997 · C.A. Grimes, W.R. Seitz, et al. · IEEE Transactions on Magnetics · 14
Pyridodiazepine Amines Are Selective Therapeutic Agents for Helicobacter pylori by Suppressing Growth through Inhibition of Glutamate Racemase but Are Predicted To Require Continuous Elevated Levels in Plasma To Achieve Clinical Efficacy
2015 · Boudewijn L. M. de Jonge, Amy Kutschke, et al. · Antimicrobial Agents and Chemotherapy · 12
Advanced Materials: Challenges and Opportunities
2000 · Michael Rooney, Jack Roberts, et al. · 7
Optimal pH 8.5 to 9 for the hydrolysis of vixotrigine and other basic substrates of carboxylesterase-1 in human liver microsomes
2021 · Joshua L. Johnson, Jiansheng Huang, et al. · Xenobiotica · 5
Discovery of heterocyclic sulfonamides as sphingosine 1-phosphate receptor 1 (S1P1) antagonists
2015 · Edward J. Hennessy, Gurmit Grewal, et al. · Bioorganic & Medicinal Chemistry Letters · 3
P796 In vitro and in vivo pharmacokinetics of 2-methylamino-benzodiazepines to treat Helicobacter pylori infections
2007 · J. Newman, M. Rooney, et al. · International Journal of Antimicrobial Agents · 1
Polymer substrates for optical chemical sensing
1996 · Michael Rooney · University of New Hampshire Scholars Repository (University of New Hampshire at Manchester) · 1
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P186 - pH dependent CES1 mediated hydrolysis of vixotrigine in human liver microsomes
2020 · Joshua Johnson, Michael Rooney, et al. · Drug Metabolism and Pharmacokinetics
Effect of age on brain exposure of P-GP substrates in neonatal rats
2019 · Michael Rooney, Kristopher King, et al. · Drug Metabolism and Pharmacokinetics
Abstract B100: Structure-based design of AZ7732 a novel in vivo active beta-alanine-derived pan-IAP inhibitor.
2013 · Jamal C. Saeh, Brian Aquila, et al. · Molecular Cancer Therapeutics
Works count: 21
Citation count: 529
H-index: 12
I10-index: 12
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