Author

I. J. Fidler

Observed names: Fidler, I Fidler, I J Fidler, I.J. Fidler, IJ FIDLER, IJ Fidler, Isaiah J. Fidler, Isaiah J. Fidler 6

Institutions: Houston Methodist, The University of Texas MD Anderson Cancer Center

Observed institutions: Houston Methodist, National Institutes of Health, Memorial Sloan Kettering Cancer Center, The University of Texas MD Anderson Cancer Center, The University of Texas System, Wayne State University, Dana-Farber Cancer Institute, Frederick National Laboratory for Cancer Research, National Cancer Institute, University of Pennsylvania

OpenAlex ID: A5111754323

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 · I J Fidler · PubMed · 1,140

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells.

1995 · R Radinsky, S Risin, et al. · PubMed · 321

Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.

1995 · K Xie, S Huang, et al. · The Journal of Experimental Medicine · 320

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Metastatic Model for Human Prostate Cancer Using Orthotopic Implantation in Nude Mice

1992 · R. A. Stephenson, C. P. N. Dinney, et al. · JNCI Journal of the National Cancer Institute · 306

Expression of interleukin-8 correlates with vascularity in human gastric carcinomas.

1998 · Y Kitadai, K Haruma, et al. · PubMed · 265

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.

1999 · Q Shi, J L Abbruzzese, et al. · PubMed · 261

Modulation of the Organ Microenvironment for Treatment of Cancer Metastasis

1995 · I. J. Fidler · JNCI Journal of the National Cancer Institute · 240

Influence of Organ Environment on Extracellular Matrix Degradative Activity and Metastasis of Human Colon Carcinoma Cells

1990 · M. Nakajima, K. Morikawa, et al. · JNCI Journal of the National Cancer Institute · 231

Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.

2000 · S Yano, H Shinohara, et al. · PubMed · 224

Involvement of macrophages in the eradication of established metastases following intravenous injection of liposomes containing macrophage activators.

1982 · I J Fidler, Z Barnes, et al. · PubMed · 193

Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells.

1991 · L M Li, R G Kilbourn, et al. · PubMed · 188

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

1989 · J Connor, C Bucana, et al. · Proceedings of the National Academy of Sciences · 186

Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages.

1980 · I J Fidler, A Raz, et al. · PubMed · 180

The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo.

1988 · D A Hume, P Pavli, et al. · The Journal of Immunology · 178

Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis.

1991 · R D Zhang, I J Fidler, et al. · PubMed · 168

Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages.

1993 · Z Dong, X Qi, et al. · The Journal of Immunology · 161

Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice

1999 · Y Kitadai, Y Takahashi, et al. · British Journal of Cancer · 157

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Experimental Nude Mouse Model of Human Colorectal Cancer Liver Metastases 2

1986 · Raffaella Giavazzi, J. Milburn Jessup, et al. · JNCI Journal of the National Cancer Institute · 152

Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.

2000 · L Xu, J Yoneda, et al. · International Journal of Oncology · 148

Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.

1994 · R K Singh, C D Bucana, et al. · PubMed · 139

Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta.

1999 · Z Dong, G Greene, et al. · PubMed · 133

Correlation of Growth Capacity of Human Tumor Cells in Hard Agarose With Their In Vivo Proliferative Capacity at Specific Metastatic Sites

1989 · L. Li, J. E. Price, et al. · JNCI Journal of the National Cancer Institute · 132

Angiogenesis and cancer metastasis.

2000 · I J Fidler · PubMed · 123

Synergistic activation by recombinant mouse interferon-gamma and muramyl dipeptide of tumoricidal properties in mouse macrophages.

1985 · I Saiki, I J Fidler · The Journal of Immunology · 123

Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor.

1999 · M D Balbay, C A Pettaway, et al. · PubMed · 115

Works count: 119

Citation count: 8,251

H-index: 47

I10-index: 77