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Stephen J. Haleen

Observed names: S J Haleen, S. Haleen, S. J. HALEEN, S. J. Haleen, S.J. Haleen, Stephen Haleen, Stephen J Haleen
OpenAlex ID: A5111761044
ETA and ETB Receptors Modulate the Proliferation of Human Pulmonary Artery Smooth Muscle Cells
2002 · Neil Davie, Stephen J. Haleen, et al. · American Journal of Respiratory and Critical Care Medicine · 312
Design of a Potent Combined Pseudopeptide Endothelin-A/Endothelin-B Receptor Antagonist, Ac- d Bhg16-Leu-Asp-Ile-[NMe]Ile-Trp21(PD 156252): Examination of Its Pharmacokinetic and Spectral Properties
1997 · Wayne L. Cody, John X. He, et al. · Journal of Medicinal Chemistry · 97
ETA and ETB Receptors Coexist on Rabbit Pulmonary Artery Vascular Smooth Muscle Mediating Contraction
1993 · D.M. Ladouceur, M.A. Flynn, et al. · Biochemical and Biophysical Research Communications · 88
PD 116,948, a highly selective A1 adenosine receptor antagonist
1987 · S.J. Haleen, R.P. Steffen, et al. · Life Sciences · 87
Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist.
1995 · E E Reynolds, J A Keiser, et al. · Journal of Pharmacology and Experimental Therapeutics · 71
In Vitro and In Vivo Studies with a Series of Hexapeptide Endothelin Antagonists
1993 · A. M. Doherty, W. L. Cody, et al. · Journal of Cardiovascular Pharmacology · 64
Effects of quinapril, a new angiotensin converting enzyme inhibitor, on left ventricular failure and survival in the cardiomyopathic hamster. Hemodynamic, morphological, and biochemical correlates.
1991 · S J Haleen, R E Weishaar, et al. · Circulation Research · 61
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Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application
1985 · Harriet W. Hamilton, Daniel F. Ortwine, et al. · Journal of Medicinal Chemistry · 60
Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists
1997 · William C. Patt, Jeremy J. Edmunds, et al. · Journal of Medicinal Chemistry · 46
Novel Selective Quinazoline Inhibitors of Endothelin Converting Enzyme-1
1998 · Kyunghye Ahn, Andre M. Sisneros, et al. · Biochemical and Biophysical Research Communications · 45
Correlation of adenosine receptor affinities and cardiovascular activity
1987 · H.W. Hamilton, M.D. Taylor, et al. · Life Sciences · 43
Defective Intracellular Calcium Handling in Monocrotaline-Induced Right Ventricular Hypertrophy: Protective Effect of Long-Term Endothelin-A Receptor Blockade with 2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl-)- 4-oxobut-2-enoate-sodium (PD 155080)
2002 · Friedrich Brunner, Gerald Wölkart, et al. · Journal of Pharmacology and Experimental Therapeutics · 30
Subclasses of cyclic GMP-specific phosphodiesterase and their role in regulating the effects of atrial natriuretic factor.
1990 · R E Weishaar, D C Kobylarz-Singer, et al. · Hypertension · 30
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Effects of selective endothelin antagonists on the hemodynamic response to cyclosporin A.
1994 · L S Davis, S J Haleen, et al. · Journal of the American Society of Nephrology · 29
Studies on Coronary Arteriopathy in Dogs Following Administration of CI-1020, an Endothelin A Receptor Antagonist
2001 · Mudher A. Albassam, Alan L. Metz, et al. · Toxicologic Pathology · 27
Selective effects of adenosine receptor agonists upon coronary resistance and heart rate in isolated working rabbit hearts
1985 · S.J. Haleen, D.B. Evans · Life Sciences · 26
Butenolide Endothelin Antagonists with Improved Aqueous Solubility
1999 · William C. Patt, Xue-Min Cheng, et al. · Journal of Medicinal Chemistry · 25
Structure-activity relationships of the potent combined endothelinA/endothelinB receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 (PD 142893): development of endothelinB receptor selective antagonists
1995 · Wayne L. Cody, John X. He, et al. · Journal of Medicinal Chemistry · 24
2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers
1988 · Michael D. Taylor, Edward W. Badger, et al. · Journal of Medicinal Chemistry · 22
The Endothelin-A-Receptor Antagonist PD180988 (CI-1034) Selectively Reverses the Pulmonary Vasoconstrictor Response to Hypoxia in the Lamb
2000 · Yashu Coe, Stephen J. Haleen, et al. · Journal of Cardiovascular Pharmacology · 21
The Endothelin A Receptor Antagonists PD 156707 (CI-1020) and PD 180988 (CI-1034) Reverse the Hypoxic Pulmonary Vasoconstriction in the Perinatal Lamb
2002 · Yashu Coe, Stephen J. Haleen, et al. · Journal of Pharmacology and Experimental Therapeutics · 20
Efficacy of CI-1020, an Endothelin-A Receptor Antagonist, in Hypoxic Pulmonary Hypertension
1998 · Stephen Haleen, Richard Schroeder, et al. · Journal of Cardiovascular Pharmacology · 17
Why Big Endothelin-1 Lacks a Vasodilator Response
1993 · S. J. Haleen, L. S. Davis, et al. · Journal of Cardiovascular Pharmacology · 17
Endothelin receptor antagonists: synthesis and structure–activity relationships of substituted benzothiazine-1,1-dioxides
1998 · K.A. Berryman, J.J. Edmunds, et al. · Bioorganic & Medicinal Chemistry · 16
Endothelin B Receptors on Human Endothelial and Smooth-Muscle Cells Show Equivalent Binding Pharmacology
1998 · Michael A. Flynn, Stephen J. Haleen, et al. · Journal of Cardiovascular Pharmacology · 14
Works count: 37
Citation count: 1,349
H-index: 20
I10-index: 26
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