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Martin Rowlands

Observed names: Martin G Rowlands, Martin G. Rowlands, MartinG Rowlands, Martin G. Rowlands, Rowlands, Martin G.
OpenAlex ID: A5111761656
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis
2008 · Suzanne A. Eccles, Andy Massey, et al. · Cancer Research · 484
Novel Steroidal Inhibitors of Human Cytochrome P45017.alpha.-Hydroxylase-C17,20-lyase): Potential Agents for the Treatment of Prostatic Cancer
1995 · Gerard A. Potter, S. Elaine Barrie, et al. · Journal of Medicinal Chemistry · 381
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
2011 · Maruf MU Ali, Tina Bagratuni, et al. · The EMBO Journal · 268
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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity
2005 · Lindsay Stimson, Martin G. Rowlands, et al. · Molecular Cancer Therapeutics · 225
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The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
2005 · Kwai-Ming J. Cheung, Thomas P. Matthews, et al. · Bioorganic & Medicinal Chemistry Letters · 221
High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity
2004 · Martin G Rowlands, Yvette M Newbatt, et al. · Analytical Biochemistry · 201
In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors
2007 · Swee Y. Sharp, Kathy Boxall, et al. · Cancer Research · 112
Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as Selective Inhibitors of Protein Kinase B through Fragment Elaboration
2008 · John J. Caldwell, Thomas G. Davies, et al. · Journal of Medicinal Chemistry · 105
Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)
2010 · Tatiana McHardy, John J. Caldwell, et al. · Journal of Medicinal Chemistry · 94
Esters of 3-Pyridylacetic Acid That Combine Potent Inhibition of 17.alpha.-Hydroxylase/C17,20-Lyase (Cytochrome P45017.alpha.) with Resistance to Esterase Hydrolysis
1995 · Martin G. Rowlands, S. Elaine Barrie, et al. · Journal of Medicinal Chemistry · 92
Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)
2017 · Nicola E. A. Chessum, Swee Y. Sharp, et al. · Journal of Medicinal Chemistry · 90
Inhibition of protein prenylation by metabolites of limonene
1999 · IanR Hardcastle, MartinG Rowlands, et al. · Biochemical Pharmacology · 88
Analogs of aminoglutethimide: selective inhibition of aromatase
1985 · Allan B. Foster, Michael Jarman, et al. · Journal of Medicinal Chemistry · 84
Discovery of 2-(6-{[(6-Fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a Class I Selective Orally Active Histone Deacetylase Inhibitor
2010 · David Moffat, Sanjay Patel, et al. · Journal of Medicinal Chemistry · 83
Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; Correlations with cytotoxicity
1990 · Martin G. Rowlands, Iris B. Parr, et al. · Biochemical Pharmacology · 80
Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B through Structure-Based Design
2007 · Alastair Donald, Tatiana McHardy, et al. · Journal of Medicinal Chemistry · 72
Analogs of aminoglutethimide: selective inhibition of cholesterol side-chain cleavage
1983 · Allan B. Foster, Michael Jarman, et al. · Journal of Medicinal Chemistry · 69
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
2016 · Matthew D. Cheeseman, Nicola E. A. Chessum, et al. · Journal of Medicinal Chemistry · 64
Cross-Coupling Reactions for the Preparation of 2-Arylfurans, 2-Benzylfuran and 2-Cinnamylfuran
1987 · Andrew Pelter, Martin Rowlands, et al. · Synthesis · 62
Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid
1990 · Raymond McCague, Martin G. Rowlands, et al. · Journal of Medicinal Chemistry · 60
3- and 4-Pyridylalkyl Adamantanecarboxylates: Inhibitors of Human Cytochrome P45017α (17α-Hydroxylase/C17,20-Lyase). Potential Nonsteroidal Agents for the Treatment of Prostatic Cancer
1996 · Ferdinand C. Y. Chan, Gerard A. Potter, et al. · Journal of Medicinal Chemistry · 58
The deuterium isotope effect for the α-hydroxylation of tamoxifen by rat liver microsomes accounts for the reduced genotoxicity of [D5-ethyl]tamoxifen
1995 · Michael Jarman, Grace K. Poon, et al. · Carcinogenesis · 54
Novel synthesis of heteroaromatic containing electroactive polyaromatics of known linkages, order, topicity and stoichiometry
1987 · Andrew Pelter, Martin Rowlands, et al. · Tetrahedron Letters · 54
Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs)
2008 · Stephen Gorsuch, Vassilios Bavetsias, et al. · Bioorganic & Medicinal Chemistry · 53
Synthesis and biochemical evaluation of analogs of aminoglutethimide based on phenylpyrrolidine-2,5-dione
1986 · Michael J. Daly, Gareth W. Jones, et al. · Journal of Medicinal Chemistry · 46
Works count: 97
Citation count: 4,049
H-index: 34
I10-index: 56
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