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T.D. Bethke

Arzneimittelforschung
2012 · T.D. Bethke · Der Pneumologe · 3,286
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD
2007 · D. C Grootendorst, S. A Gauw, et al. · Thorax · 284
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Roflumilast—An oral anti-inflammatory treatment for chronic obstructive pulmonary disease: A randomised controlled trial
2005 · K.F. Rabe, E.D. Bateman, et al. · Respiratory Medicine COPD Update · 69
Evaluation of GERD Symptoms during Therapy. Part II
2004 · H. Mönnikes, K.D. Bardhan, et al. · Digestion · 62
Evaluation of GERD Symptoms during Therapy
2007 · H. Mönnikes, K.D. Bardhan, et al. · Digestion · 32
Phosphodiesterase inhibition by enoximone in preparations from nonfailing and failing human hearts.
1992 · T Bethke, T Eschenhagen, et al. · PubMed · 30
Effects of Isomazole on Force of Contraction and Phosphodiesterase Isoenzymes I-IV in Nonfailing and Failing Human Hearts
1991 · T. Bethke, A. Klimkiewicz, et al. · Journal of Cardiovascular Pharmacology · 24
High Selectivity for Inhibition of Phosphodiesterase III and Positive Inotropic Effects of MCI-154 in Guinea Pig Myocardium
1993 · Th. Bethke, W. Meyer, et al. · Journal of Cardiovascular Pharmacology · 23
Pharmacokinetic disposition of inhaled ciclesonide and its metabolite desisobutyryl-ciclesonide in healthy subjects and patients with asthma are similar
2006 · R. Nave, K.A. Gunawardena, et al. · International Journal of Clinical Pharmacology and Therapeutics · 22
Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects
2006 · T.D. Bethke, T. Giessmann, et al. · International Journal of Clinical Pharmacology and Therapeutics · 21
High absolute bioavailability of the new oral phosphodiesterase-4 inhibitor roflumilast
2011 · T.D. Bethke, G. Lahu · International Journal of Clinical Pharmacology and Therapeutics · 20
Efficacy and safety of pantoprazole in patients with gastroesophageal reflux disease using an intravenous-oral regimen. Austrian Intravenous Pantoprazole Study Group.
1999 · H Wurzer, K Schutze, et al. · PubMed · 18
Effects of pantoprazole on endocrine function in healthy male volunteers
1994 · H. G. DAMMANN, Th. BETHKE, et al. · Alimentary Pharmacology & Therapeutics · 17
Influence of renal impairment on the pharmacokinetics of oral roflumilast: an open-label, parallel-group, single-center study
2011 · T.D. Bethke, M. Hartmann, et al. · International Journal of Clinical Pharmacology and Therapeutics · 15
Lack of pharmacokinetic drug-drug interaction between ciclesonide and erythromycin
2005 · R. Nave, A. Drollmann, et al. · International Journal of Clinical Pharmacology and Therapeutics · 15
Study investigating pharmacokinetic interaction between theophylline and roflumilast in healthy adults
2011 · G. Böhmer, C.H. Gleiter, et al. · International Journal of Clinical Pharmacology and Therapeutics · 10
Effects of the triazolopyrimidine trapidil on force of contraction, beating frequency and phosphodiesterase I--IV activity in guinea-pig hearts.
1991 · T Bethke, H Mehl, et al. · PubMed · 9
Lack of pharmacokinetic and pharmacodynamic interactions of roflumilast with (R, S)-warfarin in healthy adult subjects
2011 · N. McCracken, G. Lahu, et al. · International Journal of Clinical Pharmacology and Therapeutics · 8
Oropharyngeal deposition of inhaled ciclesonide and budesonide in healthy subjects
2003 · R. Nave, K. Zech, et al. · Journal of Allergy and Clinical Immunology · 7
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Phosphodiesterase III inhibition by MCI-154 and other cardiotonic drugs in relation to force of contraction, cAMP content and calcium sensitization in the heart
1990 · T. Bethke, W. Meyer, et al. · European Journal of Pharmacology · 7
Pharmacokinetics of ciclesonide and its active principle in asthma patients and healthy subjects after single-dose inhalation
2003 · T.D. Bethke, R. Nave, et al. · Journal of Allergy and Clinical Immunology · 6
Pantoprazole lacks interaction with the NSAID naproxen
2000 · H.-U. Schulz, M. Hartmann, et al. · Gastroenterology · 6
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Equivalent pharmacokinetics of the active metabolite of ciclesonide with and without use of a spacer for inhalation
2004 · A. Drollmann, R. Nave, et al. · Journal of Allergy and Clinical Immunology · 5
Ciclesonide 160 μg Once Daily is as Effective as Budesonide 400 μg Once Daily in Pediatric Patients with Persistent Asthma
2006 · A. von Berg, M.L. Garcia, et al. · Journal of Allergy and Clinical Immunology · 2
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Roflumilast Shows No Pharmacokinetic Interaction with Warfarin in Healthy Subjects
2004 · Andreas Huennemeyer, K. Zech, et al. · CHEST Journal · 1
Works count: 50
Citation count: 4,003
H-index: 15
I10-index: 16
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