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Koc-Kan Ho

Epigenetic Drug Discovery: Targeting DNA Methyltransferases
2011 · Jason M. Foulks, K. Mark Parnell, et al. · SLAS DISCOVERY · 158
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A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas
2014 · Jason M. Foulks, Kent J. Carpenter, et al. · Neoplasia · 98
Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth
2013 · K. Mark Parnell, Jason M. Foulks, et al. · Molecular Cancer Therapeutics · 72
4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone
1996 · Andrea Leone-Bay, Koc-Kan Ho, et al. · Journal of Medicinal Chemistry · 67
Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors
2014 · Yong Xu, Benjamin G. Brenning, et al. · ACS Medicinal Chemistry Letters · 58
Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2)
2013 · Yong Xu, Xiao-Hui Liu, et al. · Bioorganic & Medicinal Chemistry Letters · 51
Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis
2004 · Tao Guo, Anton E.P. Adang, et al. · Bioorganic & Medicinal Chemistry Letters · 46
Small molecule biaryl FSH receptor agonists. Part 1
2004 · Tao Guo, Anton E.P. Adang, et al. · Bioorganic & Medicinal Chemistry Letters · 45
Nonpeptidergic Allosteric Antagonists Differentially Bind to the CXCR2 Chemokine Receptor
2009 · Petra de Kruijf, Jane van Heteren, et al. · Journal of Pharmacology and Experimental Therapeutics · 43
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors
2012 · Koc-Kan Ho, K. Mark Parnell, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Eicosanoid regulation of debris-stimulated metastasis
2021 · Jianjun Deng, Haixia Yang, et al. · Proceedings of the National Academy of Sciences · 28
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Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists
2006 · Koc-Kan Ho, Douglas S. Auld, et al. · Bioorganic & Medicinal Chemistry Letters · 28
Structure–activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists
2010 · Ronald Palin, Lynn Abernethy, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles
2011 · Paul Ratcliffe, Lynn Abernethy, et al. · Bioorganic & Medicinal Chemistry Letters · 21
Synthesis and structure–activity relationship of 2-arylamino-4-aryl-pyrimidines as potent PAK1 inhibitors
2013 · Yong Xu, Jason M. Foulks, et al. · Bioorganic & Medicinal Chemistry Letters · 18
2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors
2009 · Andrew G. Cole, Adolph C. Bohnstedt, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model
2009 · Koc-Kan Ho, James R. Beasley, et al. · Bioorganic & Medicinal Chemistry Letters · 18
2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors
2003 · Koc-Kan Ho, Kenneth C. Appell, et al. · Bioorganic & Medicinal Chemistry Letters · 15
Targeting signal transduction with large combinatorial collections
2002 · Douglas S. Auld, David Diller, et al. · Drug Discovery Today · 14
Discovery of novel quinolinone adenosine A2B antagonists
2010 · Brian F. McGuinness, Koc-Kan Ho, et al. · Bioorganic & Medicinal Chemistry Letters · 12
Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist
2010 · Angus R. Brown, Michael Bosies, et al. · Bioorganic & Medicinal Chemistry Letters · 8
Identification and optimization of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V3 (V1b) receptor antagonists
2010 · Jeffrey J. Letourneau, Christopher M. Riviello, et al. · Bioorganic & Medicinal Chemistry Letters · 8
Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide Vasopressin V1b receptor antagonists
2011 · Susan E. Napier, Jeffrey J. Letourneau, et al. · Bioorganic & Medicinal Chemistry Letters · 7
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists
2010 · Susan E. Napier, Jeffrey J. Letourneau, et al. · Bioorganic & Medicinal Chemistry Letters · 7
Identification and hit-to-lead optimization of a novel class of CB1 antagonists
2010 · Jeffrey J. Letourneau, Patrick Jokiel, et al. · Bioorganic & Medicinal Chemistry Letters · 4
Works count: 34
Citation count: 907
H-index: 17
I10-index: 20
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