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Yukihiro Hirao

Observed names: Hirao, Yukihiro, YUKIHIRO HIRAO, Yukihiro HIRAO
Institution: Otsuka (Japan)
OpenAlex ID: A5111798419
Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo
2015 · Katsunori Sasahara, Yoshihiko Shimokawa, et al. · Drug Metabolism and Disposition · 96
Development and validation of an LC–MS/MS method for the quantitative determination of aripiprazole and its main metabolite, OPC-14857, in human plasma
2005 · Masanori Kubo, Yasuo Mizooku, et al. · Journal of Chromatography B · 88
The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired 13CO2 and Plasma [2-13C]Dihydrouracil
2006 · Lori K. Mattison, Jeanne Fourie, et al. · Clinical Cancer Research · 77
Physiologically based pharmacokinetic modelling of the three‐step metabolism of pyrimidine using13C‐uracil as anin vivoprobe
2005 · Suminobu Ito, Takeshi Kawamura, et al. · British Journal of Clinical Pharmacology · 26
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Epoxide reductase activity of mammalian liver cytosols and aldehyde oxidase
1994 · Yukihiro Hirao, Shigeyuki Kitamura, et al. · Carcinogenesis · 24
Local Gastric and Serum Concentrations of Rebamipide Following Oral Ingestion in Healthy Volunteers
2002 · Taiji Akamatsu, Naoshi Nakamura, et al. · Digestive Diseases and Sciences · 19
Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human
2021 · Hiroyuki Sasabe, Toshihisa Koga, et al. · Xenobiotica · 18
Liquid chromatography–tandem mass spectrometry method for determining tolvaptan and its nine metabolites in rat serum: application to a pharmacokinetic study
2014 · Masayuki Furukawa, Kenichi Miyata, et al. · Archives of Pharmacal Research · 16
Liquid Chromatography-Tandem Mass Spectrometry Methods for Determination of Delamanid in Mouse Plasma and Lung
2015 · Yukihiro Hirao, Toshihisa Koga, et al. · American Journal of Analytical Chemistry · 14
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In Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver Microsomes
2000 · Ken Umehara, Shoji Kudo, et al. · Drug Metabolism and Disposition · 14
Oxidative Cleavage of the Octyl Side Chain of 1-(3,4-Dichlorobenzyl)-5-Octylbiguanide (OPB-2045) in Rat and Dog Liver Preparations
2000 · Ken Umehara, Shoji Kudo, et al. · Drug Metabolism and Disposition · 12
Relationships Among Plasma [2-13c]uracil Concentrations, Breath 13co2 Expiration, and Dihydropyrimidine Dehydrogenase (dpd) Activity in the Liver in Normal and Dpd-deficient Dogs
2004 · Makoto Inada, Yukihiro Hirao, et al. · Drug Metabolism and Disposition · 11
Enantioselective analysis of tolvaptan in rat and dog sera by high-performance liquid chromatography and application to pharmacokinetic study
2014 · Masayuki Furukawa, Yuko Yamasaki, et al. · Journal of Chromatography B · 7
Desirable pharmacokinetic properties of13C-uracil as a breath test probe of gastric emptying in comparison with13C-acetate and13C-octanoate in rats
2009 · Erika Sugiyama, Makoto Inada, et al. · Scandinavian Journal of Gastroenterology · 3
Phase I Clinical Trial of 13C-Urea Breath Test (C-13UBT).
1996 · Shigeru ASAKI, Hisashi YAMAGAMI, et al. · Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics · 1
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Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human
2021 · Sasabe, Hiroyuki, Toshihisa Koga, et al. · Figshare
Hemodialysis clearance of iosimenol, a novel iso-osmolar radiographic contrast medium
2013 · Yukihiro Hirao, Eiji Kashiyama, et al. · Acta Radiologica
Mechanism of Reduction of Epoxide Compounds in Animal Body (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
1995 · SHIGEYUKI KITAMURA, YUKIHIRO HIRAO, et al. · Eisei kagaku
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Works count: 18
Citation count: 426
H-index: 11
I10-index: 12
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