Author

Fardos N.M. Naguib

Observed names: F N Naguib, F Naguib, F. N. M. NAGUIB, F. N. M. Naguib, F. Naguib, Fardos N. M. Naguib, Fardos N. Naguib, Fardos N.M Naguib, Fardos Naguib

Institution: University of Alabama at Birmingham

Observed institutions: Centre National de la Recherche Scientifique, Roger Williams Medical Center, Emory University, Kaohsiung Medical University, University of Alberta, University of Georgia, University of Alabama, University of Rhode Island, University of California, Irvine, Brown University, University of Alabama at Birmingham, Fred Hutch Cancer Center, Atlanta VA Medical Center, UAB Medicine, Syracuse University

OpenAlex ID: A5111807409

Enzymes of uracil catabolism in normal and neoplastic human tissues.

1985 · F N Naguib, M H el Kouni, et al. · PubMed · 277

The Adenosine Transporter of Toxoplasma gondii

1999 · Chi-Wu Chiang, Nicola Carter, et al. · Journal of Biological Chemistry · 80

Differences in activities and substrate specificity of human and murine pyrimidine nucleoside phosphorylases: implications for chemotherapy with 5-fluoropyrimidines.

1993 · M H el Kouni, M M el Kouni, et al. · PubMed · 79

5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens

2005 · Omar N. Al Safarjalani, Xiao-Jian Zhou, et al. · Cancer Chemotherapy and Pharmacology · 69

Potentiation of 5-fluoro-2'-deoxyuridine antineoplastic activity by the uridine phosphorylase inhibitors benzylacyclouridine and benzyloxybenzylacyclouridine.

1984 · M Y Chu, F N Naguib, et al. · PubMed · 69

5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase

1993 · Fardos N.M. Naguib, Diane L. Levesque, et al. · Biochemical Pharmacology · 68

Insertional tagging of at least two loci associated with resistance to adenine arabinoside in Toxoplasma gondii, and cloning of the adenosine kinase locus

1999 · William J. Sullivan, Chi-Wu Chiang, et al. · Molecular and Biochemical Parasitology · 59

Phenylselenenyl- and phenylthio-substituted pyrimidines as inhibitors of dihydrouracil dehydrogenase and uridine phosphorylase

1993 · Naganna M. Goudgaon, Fardos N. M. Naguib, et al. · Journal of Medicinal Chemistry · 59

Circadian rhythm of hepatic uridine phosphorylase activity and plasma concentration of uridine in mice

1990 · Mahmoud H. el Kouni, Fardos N.M. Naguib, et al. · Biochemical Pharmacology · 50

Synthesis, Biological Activity and Molecular Modeling of 6-Benzylthioinosine Analogues as Subversive Substrates ofToxoplasmagondiiAdenosine Kinase

2004 · Vikas Yadav, Chung K. Chu, et al. · Journal of Medicinal Chemistry · 49

Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii

1999 · Mahmoud H. el Kouni, Vincenzo Guarcello, et al. · Antimicrobial Agents and Chemotherapy · 45

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Circadian rhythm of orotate phosphoribosyltransferase, pyrimidine nucleoside phosphorylases and dihydrouracil dehydrogenase in mouse liver

1993 · Fardos N.M. Naguib, Soong Seng-Jaw, et al. · Biochemical Pharmacology · 43

Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands ofToxoplasma gondiiAdenosine Kinase

2008 · Young Ah Kim, Ashoke Sharon, et al. · Journal of Medicinal Chemistry · 38

Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents

2007 · Young Ah Kim, Ashoke Sharon, et al. · Biochemical Pharmacology · 36

Uridine phosphorylase inhibitors: Chemical modification of benzyloxybenzyl-barbituric acid and its effects on UrdPase inhibition

1999 · David J. Guerin, Daniel Mazeas, et al. · Bioorganic & Medicinal Chemistry Letters · 36

7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities

2008 · Omar N. Al Safarjalani, Reem H. Rais, et al. · Biochemical Pharmacology · 35

Structure-activity relationship of ligands of dihydrouracil dehydrogenase from mouse liver

1989 · Fardos N.M. Naguib, Mahmoud H. El Kouni, et al. · Biochemical Pharmacology · 34

New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers

1987 · Fardos N.M. Naguib, Mahmoud H. el Kouni, et al. · Biochemical Pharmacology · 34

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii

1996 · Mahmoud H. el Kouni, Fardos N.M. Naguib, et al. · Biochemical Pharmacology · 33

Uridine phosphorylase from Schistosoma mansoni.

1988 · M H el Kouni, F N Naguib, et al. · Journal of Biological Chemistry · 32

Uptake of Nitrobenzylthioinosine and Purine β- l -Nucleosides by Intracellular Toxoplasma gondii

2003 · Omar N. Al Safarjalani, Fardos N. M. Naguib, et al. · Antimicrobial Agents and Chemotherapy · 31

Synthesis of a new class of uridine phosphorylase inhibitors

1993 · Diane L. Levesque, Eng‐Chi Wang, et al. · Journal of Heterocyclic Chemistry · 30

Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyltransferase from Toxoplasma gondii

1995 · Fardos N.M. Naguib, Max H. Iltzsch, et al. · Biochemical Pharmacology · 26

6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities

2005 · Reem H. Rais, Omar N. Al Safarjalani, et al. · Biochemical Pharmacology · 25

Pyrimidine salvage pathways in adult Schistosoma mansoni

1990 · Mahmoud H. El Kouni, Fardos N.M. Naguib · International Journal for Parasitology · 22

Works count: 67

Citation count: 1,804

H-index: 24

I10-index: 49