Get started
Author

Mark K. Wedel

Potent Reduction of Apolipoprotein B and Low-Density Lipoprotein Cholesterol by Short-Term Administration of an Antisense Inhibitor of Apolipoprotein B
2006 · John J.P. Kastelein, Mark K. Wedel, et al. · Circulation · 357
Partial Liquid Ventilation in Adult Patients with Acute Respiratory Distress Syndrome
2005 · Robert M. Kacmarek, Herbert P. Wiedemann, et al. · American Journal of Respiratory and Critical Care Medicine · 173
Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy
2010 · Fatima Akdim, Erik S.G. Stroes, et al. · Journal of the American College of Cardiology · 164
PDF
An enema formulation of alicaforsen, an antisense inhibitor of intercellular adhesion molecule‐1, in the treatment of chronic, unremitting pouchitis
2004 · P. Miner, M. Wedel, et al. · Alimentary Pharmacology & Therapeutics · 131
A Randomized, Double-Masked, Placebo-Controlled Study of Alicaforsen, an Antisense Inhibitor of Intercellular Adhesion Molecule 1, for the Treatment of Subjects With Active Crohn’s Disease
2007 · Bruce Yacyshyn, William Y. Chey, et al. · Clinical Gastroenterology and Hepatology · 128
Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100
2008 · Rosie Z. Yu, Kristina M. Lemonidis, et al. · Biochemical Pharmacology · 127
A Phase II dose ranging, double‐blind, placebo‐controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left‐sided ulcerative colitis
2006 · S. J. H. VAN DEVENTER, M. K. WEDEL, et al. · Alimentary Pharmacology & Therapeutics · 127
PDF
Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia
2011 · Fatima Akdim, Diane L. Tribble, et al. · European Heart Journal · 123
Lack of Pharmacokinetic Interaction of Mipomersen Sodium (ISIS 301012), a 2′-O-Methoxyethyl Modified Antisense Oligonucleotide Targeting Apolipoprotein B-100 Messenger RNA, with Simvastatin and Ezetimibe
2008 · Rosie Z Yu, Richard S Geary, et al. · Clinical Pharmacokinetics · 102
Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left‐sided ulcerative colitis: a randomized, double‐blind, active‐controlled trial
2006 · P. B. MINER, M. K. WEDEL, et al. · Alimentary Pharmacology & Therapeutics · 102
PDF
Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis
2006 · P. B. MINER, R. S. GEARY, et al. · Alimentary Pharmacology & Therapeutics · 53
Lack of Pharmacokinetic Interaction for ISIS 113715, a 2???-0-Methoxyethyl Modified Antisense Oligonucleotide Targeting Protein Tyrosine Phosphatase 1B Messenger RNA, with Oral Antidiabetic Compounds Metformin, Glipizide or Rosiglitazone
2006 · Richard S Geary, JoAnn D Bradley, et al. · Clinical Pharmacokinetics · 50
Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins
2012 · Jeremy D. Furtado, Mark K. Wedel, et al. · Journal of Lipid Research · 24
PDF
Platelet kinetics in venovenous membrane oxygenation.
1975 · R G Spragg, R N Hill, et al. · PubMed · 10
Prolonged Survival in an Adult with Cystic Fibrosis
1980 · J. Scott Sanders, Timothy D. Pryor, et al. · CHEST Journal · 9
Clinical Correlation With Changing Radiographic Appearance During Partial Liquid Ventilation
2001 · Daniel P. Schuster, Neale R. Lange, et al. · CHEST Journal · 7
Po23-746 Isis 301012, an Antisense Inhibitor of Apo B, Produces Significant Additional Reduction of Ldl-c & Apob in Hypercholesterolemic Subjects on Statins Not Meeting Target
2007 · J.P. Kastelein, F. Akdim, et al. · Atherosclerosis Supplements · 5
Antisense inhibitor of ICAM-1 given as enema improves symptomatic pouchitis
2003 · Philip B. Miner, Barbara L. Bane, et al. · Gastroenterology · 3
Treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) by nasal mask.
1984 · M K Wedel, B J van Dyne, et al. · PubMed · 3
Toxic Shock Syndrome
1981 · Mark K. Wedel, Thomas K. Slack, et al. · CHEST Journal · 3
PDF
Cardiovascular Therapeutic Applications
2007 · Mark Wedel, Rosanne Crooke, et al. · CRC Press eBooks · 2
Wo7-or-3 Statin-like, Dose-dependent Reductions in Ldl-c and Apob With Isis 301012, an Antisense Inhibitor of Apob, in Subjects With Polygenic Hypercholesterolemia
2007 · E. Stein, J.D. Bradley, et al. · Atherosclerosis Supplements · 2
A child with obstructive sleep apnea.
1985 · T M Berman, M K Wedel, et al. · PubMed · 2
Accessory diaphragm.
1981 · M K Wedel, R W Dickman, et al. · PubMed · 2
Th-W49:6 Significant reduction of small dense LDL-cholesterol concentrations in healthy volunteers by antisense inhibition of apolipoprotein B
2006 · J.J.P. Kastelein, M.K. Wedel, et al. · Atherosclerosis Supplements · 1
Works count: 32
Citation count: 1,712
H-index: 13
I10-index: 14
Year
Topic
Type