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Yiding Hu

Metabolism of the Endocrine Disruptor Pesticide-Methoxychlor by Human P450s: Pathways Involving a Novel Catechol Metabolite
2002 · Yiding Hu, David Kupfer · Drug Metabolism and Disposition · 69
A Novel, Highly Selective, Tight Binding IκB Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor-κB Pathway in Arthritis-Relevant Cells and Animal Models
2009 · Gabriel Mbalaviele, Cynthia D. Sommers, et al. · Journal of Pharmacology and Experimental Therapeutics · 62
Evaluation of Aerosol Delivery of Nanosuspension for Pre-clinical Pulmonary Drug Delivery
2009 · Po-Chang Chiang, Jason W Alsup, et al. · Nanoscale Research Letters · 58
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Simultaneous Determination of LogD, LogP, and pKa of Drugs by Using a Reverse Phase HPLC Coupled with a 96-Well Plate Auto Injector
2009 · Po-Chang Chiang, Yiding Hu · Combinatorial Chemistry & High Throughput Screening · 46
Comparison of In vitro Nanoparticles Uptake in Various Cell Lines and In vivo Pulmonary Cellular Transport in Intratracheally Dosed Rat Model
2008 · Yurong Lai, Po-Chang Chiang, et al. · Nanoscale Research Letters · 41
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Enantioselective Metabolism of the Endocrine Disruptor Pesticide Methoxychlor by Human Cytochromes P450 (P450s): Major Differences in Selective Enantiomer Formation by Various P450 Isoforms
2002 · Yiding Hu, David Kupfer · Drug Metabolism and Disposition · 40
Euthanasia method for mice in rapid time-course pulmonary pharmacokinetic studies.
2009 · Adam R Schoell, Bruce R Heyde, et al. · PubMed Central · 35
Novel Tight-Binding Inhibitory Factor-κB Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo Model of Airway Inflammation
2009 · Cynthia D. Sommers, Janice M. Thompson, et al. · Journal of Pharmacology and Experimental Therapeutics · 34
Structure-Activity Relationships for Interaction with Multidrug Resistance Protein 2 (ABCC2/MRP2): The Role of Torsion Angle for a Series of Biphenyl-Substituted Heterocycles
2007 · Yurong Lai, Li Xing, et al. · Drug Metabolism and Disposition · 34
Further Studies on the Biosynthesis of the Manumycin-Type Antibiotic, Asukamycin, and the Chemical Synthesis of Protoasukamycin
2004 · Yiding Hu, Heinz G. Floss · Journal of the American Chemical Society · 29
3-Amino-4-hydroxybenzoic Acid: the Precursor of the C7N Unit in Asukamycin and Manumycin
1997 · Yiding Hu, Chris R. Melville, et al. · Journal of the American Chemical Society · 22
Evaluating the Suitability of Using Rat Models for Preclinical Efficacy and Side Effects with Inhaled Corticosteroids Nanosuspension Formulations
2010 · Po-Chang Chiang, Yiding Hu, et al. · Nanoscale Research Letters · 21
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure–activity relationship
2010 · Jin Xie, Gennadiy I. Poda, et al. · Bioorganic & Medicinal Chemistry · 16
Novel Metabolic Bioactivation Mechanism for a Series of Anti-Inflammatory Agents (2,5-Diaminothiophene Derivatives) Mediated by Cytochrome P450 Enzymes
2010 · Yiding Hu, Shengtian Yang, et al. · Drug Metabolism and Disposition · 16
Advancement of Structure-Activity Relationship of Multidrug Resistance-Associated Protein 2 Interactions
2009 · Li Xing, Yiding Hu, et al. · The AAPS Journal · 14
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Pharmacokinetic and Pharmacodynamic Evaluation of the Suitability of Using Fluticasone and an Acute Rat Lung Inflammation Model to Differentiate Lung Versus Systemic Efficacy
2009 · Po-Chang Chiang, Yiding Hu, et al. · Journal of Pharmaceutical Sciences · 13
New Type II Manumycins Produced by Streptomyces nodosus ssp. asukaensis and Their Biosynthesis.
2001 · YIDING HU, HEINZ G. FLOSS · The Journal of Antibiotics · 12
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Saturation of Multidrug-Resistant Protein 2 (Mrp2/Abcc2)-Mediated Hepatobiliary Secretion: Nonlinear Pharmacokinetics of a Heterocyclic Compound in Rats after Intravenous Bolus Administration
2009 · Yiding Hu, Kathleen E. Sampson, et al. · Drug Metabolism and Disposition · 10
Discovery of GS-2278, a Potent and Selective LPAR1 Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis
2024 · Doris T. Tang, Zhimin Du, et al. · Journal of Medicinal Chemistry · 8
CYP7A1 Gene Induction via SHP-Dependent or Independent Mechanisms can Increase the Risk of Drug-Induced Liver Injury Independently or in Synergy with BSEP Inhibition
2024 · Congrong Niu, Xiaodong Xie, et al. · Drug Metabolism and Disposition · 7
Starter Unit Specificity of the Asukamycin “Upper” Chain Polyketide Synthase and the Branched-Chain Fatty Acid Synthase of Streptomyces nodosus subsp. asukaensis
2006 · Heinz G. Floss, Yiding Hu · Heterocycles · 6
The biosynthesis of manumycin type metabolites
2000 · Yiding Hu · ResearchWorks at the University of Washington (University of Washington) · 3
Mechanism-guided untargeted-to-targeted lipidomics identifies phosphatidylcholine 38:4 in rat bile as an Abcb4/Mdr2 inhibition marker
2026 · Renmeng Liu, Zachary Rabow, et al. · Drug Metabolism and Disposition · 2
Carbon-carbon Bond Cleavage Catalyzed by Human Cytochrome P450 Enzymes: α-ketol as the Key Intermediate Metabolite in Sequential Metabolism of Olanexidine
2019 · Yiding Hu, Yi Xiao, et al. · Drug Metabolism Letters · 2
Two Branched Polar Groups and Polar Linker Moieties of Thiophene Amide Derivatives Are Essential for MRP2/ABCC2 Recognition
2010 · Yiding Hu, Kathleen E. Sampson, et al. · Drug Metabolism Letters · 2
Works count: 29
Citation count: 602
H-index: 14
I10-index: 18
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