Author

Jörg Keldenich

Observed names: J Keldenich, J. Keldenich

Observed institutions: Friedrich-Alexander-Universität Erlangen-Nürnberg, University of Regensburg, Swiss Federal Institute of Aquatic Science and Technology, Bayer (Germany)

OpenAlex ID: A5111838899

New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease

2002 · Gerald Kleymann, Rüdiger Fischer, et al. · Nature Medicine · 335

A Physiological Model for the Estimation of the Fraction Dose Absorbed in Humans

2004 · Stefan Willmann, Walter Schmitt, et al. · Journal of Medicinal Chemistry · 219

Mimicking Hypoxia to Treat Anemia: HIF-Stabilizer BAY 85-3934 (Molidustat) Stimulates Erythropoietin Production without Hypertensive Effects

2014 · Ingo Flamme, Felix Oehme, et al. · PLoS ONE · 174

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COSMOmic: A Mechanistic Approach to the Calculation of Membrane−Water Partition Coefficients and Internal Distributions within Membranes and Micelles

2008 · Andreas Klamt, Uwe Huniar, et al. · The Journal of Physical Chemistry B · 139

In Silico ADMET Traffic Lights as a Tool for the Prioritization of HTS Hits

2006 · Mario Lobell, Martin Hendrix, et al. · ChemMedChem · 110

A Physiologic Model for Simulating Gastrointestinal Flow and Drug Absorption in Rats

2003 · Stefan Willmann, Walter Schmitt, et al. · Pharmaceutical Research · 98

CypScore: Quantitative Prediction of Reactivity toward Cytochromes P450 Based on Semiempirical Molecular Orbital Theory

2009 · Matthias Hennemann, Arno Friedl, et al. · ChemMedChem · 95

Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia

2018 · Hartmut Beck, Mario Jeske, et al. · ChemMedChem · 82

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Multilamellar Liposomes and Solid-Supported Lipid Membranes (TRANSIL): Screening of Lipid-Water Partitioning Toward a High-Throughput Scale

2001 · Angelika Loidl-Stahlhofen, Thorsten Hartmann, et al. · Pharmaceutical Research · 76

Solid-Supported Biomolecules on Modified Silica Surfaces—A Tool for Fast Physicochemical Characterization and High-Throughput Screening

2001 · A. Loidl-Stahlhofen, J. Schmitt, et al. · Advanced Materials · 62

In Silico Prediction of Buffer Solubility Based on Quantum-Mechanical and HQSAR- and Topology-Based Descriptors

2006 · Andreas H. Göller, Matthias Hennemann, et al. · Journal of Chemical Information and Modeling · 34

Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: Implications for biological regulation of 5-lipoxygenase

1994 · A. Hatzelmann, R. Fruchtmann, et al. · Inflammation Research · 21

Effects of Different Pulmonary Vasodilators on Arterial Saturation in a Model of Pulmonary Hypertension

2013 · Eva Maria Becker, Johannes-Peter Stasch, et al. · PLoS ONE · 19

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Volume to dissolve applied dose (VDAD) and apparent dissolution rate (ADR): Tools to predict in vivo bioavailability from orally applied drug suspensions

2011 · Uwe Muenster, Christian Pelzetter, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 17

Biphenyls as potent vitronectin receptor antagonists. Part 3: Squaric acid amides

2007 · Klaus Urbahns, Michael Härter, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Prediction of human clearance (CL) and volume of distribution (VD)

2004 · Jörg Keldenich · Drug Discovery Today Technologies · 12

Leukotriene Synthesis Inhibitors of the Quinoline Type: Parameters for the Optimization of Efficacy

1995 · Michael Matzke, Bernd Beckermann, et al. · European Journal of Medicinal Chemistry · 9

Estimation of Physicochemical and ADME Parameters

2002 · Michael W. Härter, Jörg Keldenich, et al. · Wiley eBooks · 4

Stern potential near gold and chromium surfaces in contact with aqueous and alcoholic ammonium salt solutions

1991 · J. Keldenich, G. Peschel · Colloid & Polymer Science · 4

Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X1005. Implications for biological regulation of 5-lipoxygenase.

1994 · A Hatzelmann, R Fruchtmann, et al. · PubMed · 1

Front Cover: Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia (ChemMedChem 10/2018)

2018 · Hartmut Beck, Mario Jeske, et al. · ChemMedChem

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PK-Sim® による薬物動態シミュレーション：物理化学的性質から薬物濃度の経時的変化プロファイル

2006 · 秋山浩子, Walter Schmitt, et al. · 日本薬物動態学会年会講演要旨集第21回日本薬物動態学会年会

PK-Map TM : A Powerful Tool for Early ADME Prediction and Visualization

2004 · Stefan Willmann, Walter Schmitt, et al.

Works count: 23

Citation count: 1,528

H-index: 15

I10-index: 16