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Kevin T. Chapman

Observed names: K T Chapman, K. T. CHAPMAN, K. T. Chapman, KEVIN T. CHAPMAN, Kevin Chapman, Kevin T Chapman, k. chapman
Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Harvard University, University of California, Los Angeles, United States Army Medical Research Institute of Infectious Diseases, Merck Canada Inc. (Canada), Massachusetts Institute of Technology
OpenAlex ID: A5111853302
A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
1992 · Nancy A. Thornberry, Herbert G. Bull, et al. · Nature · 2,574
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
1997 · Nancy A. Thornberry, Thomas A. Rano, et al. · Journal of Biological Chemistry · 2,072
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Directed reduction of .beta.-hydroxy ketones employing tetramethylammonium triacetoxyborohydride
1988 · D. A. Evans, K. T. Chapman, et al. · Journal of the American Chemical Society · 952
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
2005 · Margarita Garcia-Calvo, JeanMarie Lisnock, et al. · Proceedings of the National Academy of Sciences · 770
Asymmetric Diels-Alder cycloaddition reactions with chiral .alpha.,.beta.-unsaturated N-acyloxazolidinones
1988 · David A. Evans, K. T. Chapman, et al. · Journal of the American Chemical Society · 639
Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry
1998 · Susan P. Rohrer, Elizabeth T. Birzin, et al. · Science · 457
Inactivation of Interleukin-1.beta. Converting Enzyme by Peptide (Acyloxy)methyl Ketones
1994 · Nancy A. Thornberry, Erin P. Peterson, et al. · Biochemistry · 266
A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE)
1997 · Thomas A. Rano, Tracy Timkey, et al. · Chemistry & Biology · 260
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The directed reduction of β-hydroxy ketones employing Me4NHB(OAc)3
1986 · David A. Evans, Kevin T. Chapman · Tetrahedron Letters · 185
Convenient and inexpensive procedure for oxidation of secondary alcohols to ketones
1980 · Robert V. Stevens, Kevin T. Chapman, et al. · The Journal of Organic Chemistry · 178
Anthrax lethal factor inhibition
2005 · W. L. Shoop, Y. Xiong, et al. · Proceedings of the National Academy of Sciences · 172
New asymmetric Diels-Alder cycloaddition reactions. Chiral .alpha.,.beta.-unsaturated carboximides as practical chiral acrylate and crotonate dienophile synthons
1984 · D. A. Evans, K. T. Chapman, et al. · Journal of the American Chemical Society · 166
Further studies on the utility of sodium hypochlorite in organic synthesis. Selective oxidation of diols and direct conversion of aldehydes to esters
1982 · Robert V. Stevens, Kevin T. Chapman, et al. · Tetrahedron Letters · 145
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2
1998 · Lihu Yang, Scott C. Berk, et al. · Proceedings of the National Academy of Sciences · 128
Transition State π‐Solvation by Aromatic Rings: An Electronic Contribution to Diels–Alder Reaction Diastereoselectivity
1987 · David A. Evans, Kevin T. Chapman, et al. · Angewandte Chemie International Edition in English · 115
A Novel Glucagon Receptor Antagonist Inhibits Glucagon-Mediated Biological Effects
2004 · Sajjad A. Qureshi, Mari Rios Candelore, et al. · Diabetes · 109
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Solid phase synthesis of aryl ethers via the mitsunobu reaction
1995 · Thomas A. Rano, Kevin T. Chapman · Tetrahedron Letters · 102
A remarkable effect of solvent size on the stability of a molecular complex
1989 · Kevin T. Chapman, W. Clark Still · Journal of the American Chemical Society · 100
A general method for the solid phase synthesis of ureas
1994 · Steven M. Hutchins, Kevin T. Chapman · Tetrahedron Letters · 96
Fischer indole synthesis on a solid support
1996 · Steven M. Hutchins, Kevin T. Chapman · Tetrahedron Letters · 90
Synthesis of a potent, reversible inhibitor of interleukin-1β converting enzyme
1992 · Kevin T. Chapman · Bioorganic & Medicinal Chemistry Letters · 83
Dendrimer-supported combinatorial chemistry.
1996 · R M Kim, M Manna, et al. · Proceedings of the National Academy of Sciences · 76
1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia
2012 · Petr Vachal, Shouwu Miao, et al. · Journal of Medicinal Chemistry · 67
Inhibition of Stromelysin-1 (MMP-3) by P1‘-Biphenylylethyl Carboxyalkyl Dipeptides
1997 · Craig K. Esser, Robert L. Bugianesi, et al. · Journal of Medicinal Chemistry · 67
Solid phase synthesis of aryl amines
1996 · Christopher A. Willoughby, Kevin T. Chapman · Tetrahedron Letters · 66
Works count: 119
Citation count: 12,010
H-index: 41
I10-index: 94
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