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Sean W. Clark
Observed names:
S W Clark,
Sean Clark
Observed institutions:
University of California, Los Angeles,
Princeton University,
Amicus Therapeutics (United States)
OpenAlex ID:
A5111886819
Centractin is an actin homologue associated with the centrosome
1992
·
Sean W. Clark
, David I. Meyer
·
Nature
·
158
A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
2014
·
Franziska Richter
, Sheila M. Fleming
, et al.
·
Neurotherapeutics
·
109
PDF
ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle.
1994
·
S W Clark
, D I Meyer
·
The Journal of Cell Biology
·
103
Formation of transitory intrachain and interchain disulfide bonds accompanies the folding and oligomerization of simian virus 40 Vp1 in the cytoplasm
2002
·
Peggy P. Li
, Akira Nakanishi
, et al.
·
Proceedings of the National Academy of Sciences
·
64
Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.
1994
·
S W Clark
, O Staub
, et al.
·
Molecular Biology of the Cell
·
44
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model
2021
·
Nicole K. Polinski
, Terina N. Martinez
, et al.
·
PLoS ONE
·
37
PDF
Glucosylceramide and Glucosylsphingosine Quantitation by Liquid Chromatography-Tandem Mass Spectrometry to Enable In Vivo Preclinical Studies of Neuronopathic Gaucher Disease
2017
·
Rick Hamler
, Nastry Brignol
, et al.
·
Analytical Chemistry
·
28
Arp10p Is a Pointed-End-associated Component of Yeast Dynactin
2005
·
Sean W. Clark
, Mark D. Rose
·
Molecular Biology of the Cell
·
21
The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models
2022
·
Nicole K. Polinski
, Terina N. Martinez
, et al.
·
Disease Models & Mechanisms
·
17
In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord
2024
·
Killian S. Hanlon
, Ming Cheng
, et al.
·
Molecular Therapy
·
13
Alanine Scanning of Arp1 Delineates a Putative Binding Site for Jnm1/Dynamitin and Nip100/p150Glued
2005
·
Sean W. Clark
, Mark D. Rose
·
Molecular Biology of the Cell
·
12
Long lost cousins of actin
1993
·
Sean W. Clark
, David I. Meyer
·
Current Biology
·
9
An in vitro and in vivo efficacy evaluation of gene therapy candidate SBT101 in mouse models of adrenomyeloneuropathy and in NHPs
2024
·
Vidyullatha Vasireddy
, Casey A. Maguire
, et al.
·
Molecular Therapy — Methods & Clinical Development
·
6
Glucosylceramide Quantitation in Normal and Glucocerebrosidase-Deficient Mouse Brain and Human Cell Lines
2012
·
Nastry Brignol
, Kate Chang
, et al.
·
Molecular Genetics and Metabolism
·
5
The origins of glucosylsphingosine in Gaucher disease
2013
·
John Flanagan
, Brian Ranes
, et al.
·
Molecular Genetics and Metabolism
·
4
Exploring the Use of Pharmacological Chaperone AT3375 Alone and in Combination with Recombinant human ß-Glucosidase for Gaucher Disease
2012
·
Richie Khanna
, Lee Pellegrino
, et al.
·
Molecular Genetics and Metabolism
·
3
In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord
2023
·
Killian S. Hanlon
, Ming Cheng
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
2
PDF
Glucosylceramide and glucosylsphingosine quantitation by liquid chromotography-tandem mass spectrometry to enable studies of neuronopathic Gaucher disease
2014
·
Rick Hamler
, Nastry Brignol
, et al.
·
Molecular Genetics and Metabolism
·
2
An AAV Encoding Human ABCD1 Shows Dose-Responsive Expression and Function Following Spinal Cord Delivery in a Rodent Model of Adrenomyeloneuropathy (P1-1.Virtual)
2022
·
Honggeun Park
, Tony del Rio
, et al.
·
Neurology
Preclinical Pharmacology and Toxicology of intrathecally infused AAV9-hABCD1, a gene therapy candidate for AMN, in Non-Human Primates (S29.002)
2022
·
Vidyullatha Vasireddy
, Sean Clark
, et al.
·
Neurology
Optimization of intrathecal delivery of an infused AAV9 vector for delivery of a gene therapy candidate for Adrenomyeloneuropathy (AMN) in Non-Human Primates (NHP) (P12-13.008)
2022
·
Vidyullatha Vasireddy
, Sean Clark
, et al.
·
Neurology
Improved pharmacological chaperones for the treatment of neuronopathic Gaucher and Parkinson's disease
2011
·
Sean Clark
, Gary Lee
, et al.
·
Molecular Genetics and Metabolism
29. Genetic and pharmacological chaperone modulation of brain GCase activity affects synuclein accumulation in mice
2010
·
Sean Clark
, Ying Sun
, et al.
·
Molecular Genetics and Metabolism
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Works count:
23
Citation count:
637
H-index:
11
I10-index:
11
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