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Stefan von Berg
Observed names:
Stefan Berg,
Stefan Von Berg,
Stefan von Berg
Institution:
AstraZeneca (United Kingdom)
Observed institutions:
AstraZeneca (United Kingdom),
AstraZeneca (Sweden),
RWTH Aachen University
OpenAlex ID:
A5111915957
Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418
2003
·
Ratan Bhat
, Yafeng Xue
, et al.
·
Journal of Biological Chemistry
·
567
PDF
A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation
2009
·
Dominik Paquet
, Ratan Bhat
, et al.
·
Journal of Clinical Investigation
·
285
Discovery of Novel Potent and Highly Selective Glycogen Synthase Kinase-3β (GSK3β) Inhibitors for Alzheimer’s Disease: Design, Synthesis, and Characterization of Pyrazines
2012
·
Stefan Berg
, Margareta Bergh
, et al.
·
Journal of Medicinal Chemistry
·
163
Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease
2012
·
Fredrik Jeppsson
, Susanna Eketjäll
, et al.
·
Journal of Biological Chemistry
·
138
PDF
AZD 1080, a novel GSK 3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans
2013
·
Biljana Georgievska
, Johan Sandin
, et al.
·
Journal of Neurochemistry
·
124
Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid Peptides
2012
·
Britt-Marie Swahn
, Karin Kolmodin
, et al.
·
Journal of Medicinal Chemistry
·
105
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ
2015
·
Roine I. Olsson
, Yafeng Xue
, et al.
·
ChemMedChem
·
67
New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain
2012
·
Ylva Gravenfors
, Jenny Viklund
, et al.
·
Journal of Medicinal Chemistry
·
65
Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy
2012
·
Britt-Marie Swahn
, Jörg Holenz
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
47
Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
2018
·
Frank Narjes
, Yafeng Xue
, et al.
·
Journal of Medicinal Chemistry
·
43
Revisiting the peripheral sink hypothesis: inhibiting BACE 1 activity in the periphery does not alter β‐amyloid levels in the CNS
2014
·
Biljana Georgievska
, Susanne Gustavsson
, et al.
·
Journal of Neurochemistry
·
43
(R)-(+)-2-[[[3-(Morpholinomethyl)-2H-chromen-8-yl]oxy]methyl]morpholine Methanesulfonate: A New Selective Rat 5-Hydroxytryptamine1B Receptor Antagonist
1998
·
Stefan Berg
, Lars-Gunnar Larsson
, et al.
·
Journal of Medicinal Chemistry
·
40
AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2
2021
·
Frank Narjes
, Antonio Llinas
, et al.
·
Journal of Medicinal Chemistry
·
34
Carbamate ester derivatives as potential prodrugs of the presynaptic dopamine autoreceptor agonist (-)-3-(3-hydroxyphenyl)-N-propylpiperidine
1987
·
Seth Olov Thorberg
, Stefan Berg
, et al.
·
Journal of Medicinal Chemistry
·
33
Synthesis of Highly Enantioenriched CompoundsviaIron Mediated Allylic Substitutions
1997
·
Dieter Enders
, Bernd Jandeleit
, et al.
·
Synlett
·
31
Iron-Mediated Allylic Substitutions with Complete Chirality Transfer. Synthesis of Functionalized γ-Substituted Alkenylsulfones of High Enantiomeric Purity
1996
·
Dieter Enders
, Stefan von Berg
, et al.
·
Synlett
·
31
Iron-Mediated Allylic Substitution Reactions with Chirality Transfer. Stereochemistry of the Formation of Diastereo- and Enantiomerically Enriched Olefinic and Allylic Tetracarbonyl Iron Complexes
2001
·
Dieter Enders
, Bernd Jandeleit
, et al.
·
Organometallics
·
27
Evidence for dimeric BACE-mediated APP processing
2010
·
Shaobo Jin
, Karin Agerman
, et al.
·
Biochemical and Biophysical Research Communications
·
24
Combining an amyloid‐beta (Aβ) cleaving enzyme inhibitor with a γ‐secretase modulator results in an additive reduction of Aβ production
2014
·
Kia Strömberg
, Susanna Eketjäll
, et al.
·
FEBS Journal
·
23
Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
2019
·
Stefan von Berg
, Yafeng Xue
, et al.
·
ACS Medicinal Chemistry Letters
·
22
A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression
2019
·
Mei Ding
, Johan Brengdahl
, et al.
·
ACS Chemical Biology
·
15
Population PKPD Modeling of BACE1 Inhibitor-Induced Reduction in Aβ Levels In Vivo and Correlation to In Vitro Potency in Primary Cortical Neurons from Mouse and Guinea Pig
2013
·
Juliette Janson
, Susanna Eketjäll
, et al.
·
Pharmaceutical Research
·
11
“Chirality transfer” in iron-mediated dienylic substitutions via highly enantiomerically enriched planar chiral 1-phenylsulfonyl-substituted tricarbonyl(η5-pentadienyl) iron(1 +) complexes
1997
·
Dieter Enders
, Bernd Jandeleit
, et al.
·
Journal of Organometallic Chemistry
·
11
GSK-3 Inhibitors for the Treatment of Alzheimer's Disease
2007
·
Ratan V. Bhat
, Stefan Berg
, et al.
·
Springer eBooks
·
7
Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
2013
·
Anders Lindgren
, Göran Eklund
, et al.
·
Drug Metabolism and Disposition
·
6
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Works count:
34
Citation count:
2,293
H-index:
22
I10-index:
26
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