Author

Kathleen M. Welch

Observed names: K M Welch, K. M. WELCH, K. M. Welch, K.M. WELCH, K.M. Welch, Kathleen Welch

Institution: Pfizer (United States)

Observed institution: Pfizer (United States)

OpenAlex ID: A5111951006

Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist.

1995 · E E Reynolds, J A Keiser, et al. · Journal of Pharmacology and Experimental Therapeutics · 71

In Vitro and In Vivo Studies with a Series of Hexapeptide Endothelin Antagonists

1993 · A. M. Doherty, W. L. Cody, et al. · Journal of Cardiovascular Pharmacology · 64

Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists

1997 · William C. Patt, Jeremy J. Edmunds, et al. · Journal of Medicinal Chemistry · 46

The Discovery of (2R,4R)‐N‐(4‐chlorophenyl)‐N‐ (2‐fluoro‐4‐(2‐oxopyridin‐1(2H)‐yl)phenyl)‐4‐methoxypyrrolidine‐1,2‐dicarboxamide (PD 0348292), an Orally Efficacious Factor Xa Inhibitor

2007 · Jeffrey T. Kohrt, Christopher F. Bigge, et al. · Chemical Biology & Drug Design · 39

Pharmacological Differences Between Rat and Human Endothelin B Receptors

1995 · E.E. Reynolds, O. Hwang, et al. · Biochemical and Biophysical Research Communications · 29

Butenolide Endothelin Antagonists with Improved Aqueous Solubility

1999 · William C. Patt, Xue-Min Cheng, et al. · Journal of Medicinal Chemistry · 25

Structure-activity relationships of the potent combined endothelinA/endothelinB receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 (PD 142893): development of endothelinB receptor selective antagonists

1995 · Wayne L. Cody, John X. He, et al. · Journal of Medicinal Chemistry · 24

Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro

2006 · W.R. GOULD, T.B. MCCLANAHAN, et al. · Journal of Thrombosis and Haemostasis · 22

Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption

2007 · Jeffrey A. Pfefferkorn, Scott D. Larsen, et al. · Bioorganic & Medicinal Chemistry Letters · 21

The Endothelin-A-Receptor Antagonist PD180988 (CI-1034) Selectively Reverses the Pulmonary Vasoconstrictor Response to Hypoxia in the Lamb

2000 · Yashu Coe, Stephen J. Haleen, et al. · Journal of Cardiovascular Pharmacology · 21

The Endothelin A Receptor Antagonists PD 156707 (CI-1020) and PD 180988 (CI-1034) Reverse the Hypoxic Pulmonary Vasoconstriction in the Perinatal Lamb

2002 · Yashu Coe, Stephen J. Haleen, et al. · Journal of Pharmacology and Experimental Therapeutics · 20

Efficacy of CI-1020, an Endothelin-A Receptor Antagonist, in Hypoxic Pulmonary Hypertension

1998 · Stephen Haleen, Richard Schroeder, et al. · Journal of Cardiovascular Pharmacology · 17

Synthesis and structure-activity relationships of 9-substituted acridines as endothelin-A receptor antagonists

1996 · X.-M. Cheng, C. Lee, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Res-701-1, synthesis and a reevaluation of its effects on the endothelin receptors

1995 · John X. He, Wayne L. Cody, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Structure‐based Drug Design of Pyrrolidine‐1, 2‐dicarboxamides as a Novel Series of Orally Bioavailable Factor Xa Inhibitors

2007 · Chad A. Van Huis, Christopher F. Bigge, et al. · Chemical Biology & Drug Design · 16

The discovery of glycine and related amino acid-based factor Xa inhibitors

2006 · Jeffrey T. Kohrt, Kevin J. Filipski, et al. · Bioorganic & Medicinal Chemistry · 16

Endothelin receptor antagonists: synthesis and structure–activity relationships of substituted benzothiazine-1,1-dioxides

1998 · K.A. Berryman, J.J. Edmunds, et al. · Bioorganic & Medicinal Chemistry · 16

Endothelin B Receptors on Human Endothelial and Smooth-Muscle Cells Show Equivalent Binding Pharmacology

1998 · Michael A. Flynn, Stephen J. Haleen, et al. · Journal of Cardiovascular Pharmacology · 14

γ-Carbamate butenolide analogues as potent ETA selective endothelin receptor antagonists and prodrugs

1997 · William C. Patt, Billy R. Reisdorph, et al. · Bioorganic & Medicinal Chemistry Letters · 3

Structure-activity and biophysical studies of the C-terminal hexapeptide of endothelin

1995 · Daniele M. Leonard, Michael D. Reily, et al. · Bioorganic & Medicinal Chemistry Letters · 3

Assessment of Endothelin Receptor Subtype-Mediated Increases of [Ca2+]i in Distinct Rat Cell Types Using Fluorimetric Imaging

1998 · D. J. Dooley, J. J. Geer, et al. · Journal of Cardiovascular Pharmacology · 2

Structure-activity and modeling studies of tryptophan-modified peptidyl antagonists of endothelin

1994 · J. V. N. Vara Prasad, W. L. Cody, et al. · Springer eBooks · 2

Inhibition of Factors Xa and Iia Results in Synergistic Inhibition of Thrombin Generation with Minimal Clot Time Elevation.

2005 · Kathleen M. Welch, Kamlai Saiya-Cork, et al. · Blood · 1

Endothelin antagonists: The rational design of combined and ETB receptor subtype selective antagonists

1994 · W. L. Cody, A. M. Doherty, et al. · Springer eBooks · 1

ChemInform Abstract: Synthesis and Structure‐Activity Relationships of 9‐Substituted Acridines as Endothelin‐A Receptor Antagonists.

1997 · X.‐M. CHENG, C. LEE, et al. · ChemInform

Works count: 26

Citation count: 507

H-index: 16

I10-index: 18