Author

Ernie Harpur

Observed name: Ernie S. Harpur

Institution: Newcastle University

Observed institutions: University of Liverpool, University of Lancashire, Manchester Academic Health Science Centre, University of Manchester, MRC Centre for Regenerative Medicine, Sanofi (United Kingdom), University of Bath, Newcastle University, University of Edinburgh

OpenAlex ID: A5111962045

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

2006 · Lutz Müller, Robert J. Mauthe, et al. · Regulatory Toxicology and Pharmacology · 464

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

2010 · Frank Dieterle, Frank Sistare, et al. · Nature Biotechnology · 410

Biological Qualification of Biomarkers of Chemical-Induced Renal Toxicity in Two Strains of Male Rat

2011 · Ernie Harpur, Daniela Ennulat, et al. · Toxicological Sciences · 121

Towards consensus practices to qualify safety biomarkers for use in early drug development

2010 · Frank D Sistare, Frank Dieterle, et al. · Nature Biotechnology · 120

Evaluation of Novel Biomarkers of Nephrotoxicity in Two Strains of Rat Treated with Cisplatin

2010 · Jean-Charles Gautier, Björn Riefke, et al. · Toxicologic Pathology · 87

MicroRNA-122: A Novel Hepatocyte-Enriched in vitro Marker of Drug-Induced Cellular Toxicity

2014 · Richard Kia, Lorna Kelly, et al. · Toxicological Sciences · 41

Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

2020 · Brian N Chorley, Heidrun Ellinger-Ziegelbauer, et al. · Toxicological Sciences · 32

Normal Ranges and Variability of Novel Urinary Renal Biomarkers in Sprague-Dawley Rats

2014 · Jean-Charles Gautier, Thierry Gury, et al. · Toxicologic Pathology · 29

Qualified kidney biomarkers and their potential significance in drug safety evaluation and prediction

2012 · Hong-Guang Xie, Shu-Kui Wang, et al. · Pharmacology & Therapeutics · 29

Comparison between Male and Female Sprague-Dawley Rats in the Response of Urinary Biomarkers to Injury Induced by Gentamicin

2014 · Jean-Charles Gautier, Thierry Gury, et al. · Toxicologic Pathology · 27

Biomarkers of Collecting Duct Injury in Han-Wistar and Sprague-Dawley Rats Treated with N-Phenylanthranilic Acid

2012 · Graham R. Betton, Daniela Ennulat, et al. · Toxicologic Pathology · 25

Differential expression and ciprofibrate induction of hepatic UDP-glucuronyltransferases for thyroxine and triiodothyronine in Fischer rats

1991 · Theo J. Visser, Ellen Kaptein, et al. · Biochemical Pharmacology · 24

Evaluation of Renal Function and Injury

2017 · Denise Bounous, Ernie Harpur · CRC Press eBooks · 4

Qualification of safety biomarkers for use in drug development: What has been achieved and what is the path forward?

2017 · Ernie Harpur, Elizabeth Gribble Walker · Current Opinion in Toxicology · 3

MicroRNA-122: A Novel Hepatocyte-Enriched in vitro Marker of Drug-Induced Cellular Toxicity

2015 · Richard Kia, Lorna Kelly, et al. · Newcastle University ePrints (Newcastle Univesity)

Renal Biomarker Qualification

2013 · Syril Pettit, Ernie Harpur · Elsevier eBooks

2013 · Shashi Amur, Jiri Aubrecht, et al. · Elsevier eBooks

Biomarkers in the drug development process: Report from workshop discussions

2008 · Alain J. van Gool, Per Spindler, et al. · Regulatory Toxicology and Pharmacology

Works count: 19

Citation count: 1,416

H-index: 12

I10-index: 12